Article
Materials Science, Ceramics
Hua-Liang Yu, Li-Qin Liu, Ying-Wu Zhou, Xiao-Ling Xue, Xiao-Hong Yuan, Yao-Guo Shen, Zhi-Qun Liu, Hua-Min Chen, Chun-Lei Huang
Summary: Fabric-based nano semiconductor photocatalysts have attracted much attention recently. In this study, Ag2O/ZnO nanorod (NR)/Al-ZnO p-type/high resistivity/n-type (P-HR-N) heterojunction arrays were used to modify polyester fibers. The Al-ZnO seed layer was sputtered on the fibers and Al doping was employed to change the work function (WF) of the ZnO film. The resulting P-HR-N heterojunction sample showed enhanced photocatalytic performance due to the high and widened built-in electric field (BEF) in the multilayer film.
CERAMICS INTERNATIONAL
(2023)
Article
Food Science & Technology
Anju Boora Khatkar, Amarjeet Kaur, Sanju Bala Dhull, Sunil Kumar Khatkar, Nitin Mehta, Jaspreet Kaur, Gulden Goksen
Summary: This study enriched instant noodles with ultrasound-modified whey protein and evaluated its effects on physical, technological, cooking, and sensory attributes. The sonicated whey protein improved water absorption capacity, solubility, gel properties, dough handling, and overall quality of instant noodles.
FOOD SCIENCE & NUTRITION
(2023)
Article
Engineering, Manufacturing
Ran An, Yanbei Hou, Pengfei Tan, Mei Chen, Lihua Zhao, Kun Zhou
Summary: In this work, surface-modified zinc oxide nanorods (SMZnO) were synthesized and incorporated into polyamide 12 (PA12) powder to enhance the mechanical properties of the MJF-printed parts. Compared to ZnO, SMZnO exhibited better dispersion, resulting in markedly enhanced mechanical performances. This work provides a novel and facile approach for the additive manufacturing of polymeric nanocomposites with superior mechanical performance.
VIRTUAL AND PHYSICAL PROTOTYPING
(2023)
Article
Materials Science, Ceramics
L. A. Ma, Y. B. Chen, X. Y. Ye, L. Sun, Z. H. Wei, L. Huang, H. X. Chen, Q. T. Wang, E. G. Chen
Summary: ZnO nanorod arrays were grown on carbon cloth using a hydrothermal method, followed by deposition of titanium nitride nanoparticles. The field emission performance of ZnO nanorods was found to depend on the thickness of the TiN coating, with ZnO/TiN240 core-shell arrays exhibiting improved properties.
CERAMICS INTERNATIONAL
(2021)
Article
Chemistry, Analytical
Rasha S. Hanafi, Michael Laemmerhofer
Summary: This study proposes an advanced combined derivatization/solvent-less extraction procedure from plasma followed by rapid GC-MS detection. The sample pretreatment protocol based on aldehyde derivatization with methoxyamine under aqueous conditions followed by HS-SPME is faster compared to methods in the literature. The developed HS-SPME-GC-MS method was validated and applied for the targeted determination of lipid peroxidation aldehyde metabolites in plasma of cardiovascular patients. The concentrations of hexanal, malondialdehyde, and hydroxynonenal were significantly higher in patients, while citral was significantly lower.
ANALYTICA CHIMICA ACTA
(2022)
Article
Nanoscience & Nanotechnology
Xiaoyu Xie, Ru Wang, Yi Ma, Jinping Chen, Qiannan Cui, Zengliang Shi, Zhiyong Li, Chunxiang Xu
Summary: This study investigates the use of MXene nanosheets as a bifunctional surface modifier for enhancing the performance of ZnO nanorod arrays in PEC water oxidation. The MXene nanosheets act as a hole transfer material and combine with ZnO nanorods to construct a heterojunction, inhibiting the recombination of photogenerated charges and improving charge separation. Additionally, the MXene nanosheets function as a photothermal material and generate heat under near-infrared irradiation, elevating the surface temperature of the photoanodes and accelerating charge transfer.
ACS APPLIED NANO MATERIALS
(2022)
Article
Engineering, Electrical & Electronic
Sheng-Joue Young, L. T. Lai
Summary: In this study, pure ZnO and Au nanoparticle-modified ZnO nanorods were prepared on a glass substrate through the hydrothermal method and used to fabricate humidity sensors. Analysis of crystal and optical properties showed that the ANM ZnO nanorods had better humidity sensing performance compared to pure ZnO nanorods. The results demonstrated that Au nanoparticle adsorption effectively improved the humidity sensing properties.
IEEE TRANSACTIONS ON ELECTRON DEVICES
(2021)
Article
Chemistry, Physical
Mohamed S. Selim, Sherif A. El-Safty, A. Abbas, Mohamed A. Shenashen
Summary: A ternary nanocomposite of PDMS/GO-ZnO was designed for superhydrophobic and anticorrosion properties, with the silicone composite containing 1 wt.% of GO-ZnO hybrid nanofillers showing excellent coating performance.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Biophysics
Dongmei He, Xiangyu Zhang, Xiaohong Yao, Yongqiang Yang
Summary: Light-triggered antibacterial therapy using carbon dots and titanium dioxide nanorods shows improved antibacterial ability of titanium implants under visible light and near-infrared light, and enhances the adhesion and diffusion of bone marrow mesenchymal stem cells.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Biochemistry & Molecular Biology
Chengshuang Wang, Jie Zhang, Jiahao Chen, Jingwen Shi, Yanteng Zhao, Meng He, Liang Ding
Summary: This study develops environmentally friendly bio-based waterborne polyurethane (WPU) coatings by modifying them with chitosan-modified zinc oxide (CS-ZnO) nanoparticles. The results show that the addition of CS-ZnO improves the strength and thermal stability of the coatings, but reduces their optical transparency and wettability.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Analytical
Baosheng Du, Meng Zhang, Jifei Ye, Diankai Wang, Jianhui Han, Tengfei Zhang
Summary: Novel optical gas-sensing materials were fabricated by hydrothermal synthesis and magnetron sputtering to develop Au nanoparticle (NP)-modified ZnO nanorod (NR) arrays on Si substrates. The optical performance of ZnO NR could be controlled by annealing temperature and Au sputtering time. The Au/ZnO samples exhibited significant variation in intensity of ultraviolet (UV) emission (at ~390 nm) in the photoluminescence (PL) spectra when exposed to trace amounts of oxygen. Based on this mechanism, ZnO NR-based oxygen gas sensing via PL spectra variation showed excellent performance with a wide linear detection range, high response value, and 1% oxygen content sensitivity detection limit at 225 degrees C. This outstanding optical oxygen-sensing performance can be attributed to the large surface area to volume ratio, high crystal quality, and high UV emission efficiency of the Au NP-modified ZnO NR arrays. Density functional theory (DFT) simulation confirmed that Au NPs modified the ZnO NR surface, causing a change in charge at the interface and the lowest adsorption energy for oxygen molecules in the Au/ZnO structure. These findings suggest that Au NP-modified ZnO NR have promising potential for high-performance optical gas-sensing applications.
Article
Materials Science, Ceramics
Amel Muhson Naji, Sahira Hassan Kareem, Abbas Hasan Faris, Mustafa K. A. Mohammed
Summary: In this study, the efficient strategy of utilizing polyaniline as an additive improved the quality and stability of the perovskite photoactive layer, resulting in optimized crystallinity and reduced trap density. The introduction of polyaniline enhanced the interfacial contact between materials, leading to higher efficiency and stability in the photovoltaic cells. This approach demonstrates the potential for enhanced performance and long-term stability in perovskite solar cells.
CERAMICS INTERNATIONAL
(2021)
Article
Materials Science, Textiles
SubramaniaWarrier Sumi, NarayananNair Unnikrishnan, Lea Mathew
Summary: The growing awareness of the environment has led to the development of sustainable concepts and designs using locally available natural materials. Natural fibers are widely used in engineering, but the effects of surface modification on the environment need further investigation.
JOURNAL OF NATURAL FIBERS
(2022)
Article
Chemistry, Physical
Dongwan Kim, Jae-Young Leem
Summary: In this study, a MoS2/ZnO heterostructure with excellent UV photoresponse characteristics was successfully synthesized, with the MoS2 concentration of 0.2 M showing the best performance.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Article
Engineering, Mechanical
Y. J. Xu, Y. Ma, Y. C. Xie, Y. Zhou, H. Zhang, G. Y. Huang
Summary: The preparation process of ZnO-modified aramid fabrics was optimized in this study. The mechanical properties and interyarn friction of the modified fabrics were improved with increasing concentration of preparation solution and addition of coupling agent. The ballistic properties of the modified fabric were also enhanced, and the Z2 fabric with coupling agent showed the best performance with increased limiting velocities and minimal increase in areal density.
INTERNATIONAL JOURNAL OF IMPACT ENGINEERING
(2023)
Article
Chemistry, Multidisciplinary
Jiankun Huang, Jingbin Zeng, Xue Zhang, Gengchen Guo, Rui Liu, Zifeng Yan, Yadong Yin
Summary: This study introduces a hybrid aerogel/hydrogel sensor with high sensitivity and broad sensing range, integrating polypyrrole aerogel with PAAm hydrogel. The sensor demonstrates linear response, high sensitivity, and stable performance over a wide pressure range, making it ideal for monitoring pressures from human physiological signals to significant stress exerted by vehicles.
Article
Nanoscience & Nanotechnology
Fangdou Zhang, Kaiwen Liu, Honglin Li, Shuhua Cui, Dongzhi Zhang, Jingbin Zeng, Zifeng Yan
Summary: The gas sensing performance of metal oxides can be enhanced by the development of a PbMoO4/MoO3 heterostructure, which improves the response to TMA and reduces the working temperature.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Analytical
Penghui Liang, Qi Guo, Tianyu Zhao, Cong-Ying Wen, Zhangyu Tian, Yanxue Shang, Jinyan Xing, Yongzhong Jiang, Jingbin Zeng
Summary: This paper presents a dual-mode lateral flow immunoassay (LFIA) based on Ag-MBA@Au nanoparticles for colorimetric and SERS detection of SARS-CoV-2 IgG. The method shows high sensitivity, good reproducibility, and specificity, and demonstrates excellent consistency in clinical serum sample testing.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Xinyi Liang, Xu Du, Ao Liu, Zhixiong Cai, Jingwen Li, Maosheng Zhang, Qingxiang Wang, Jingbin Zeng
Summary: This study proposes a plasmonic nanosenosr for the detection of mercury(II) in natural samples. The sensor shows high selectivity and feasibility, making it suitable for analyzing complex matrices directly.
CHINESE CHEMICAL LETTERS
(2023)
Article
Chemistry, Physical
Meng-Xuan Li, Ya-Nan Zhou, Yi-Wen Dong, Xin Liu, Ren-Ni Luan, Bin Liu, Jing-Bin Zeng, Yong-Ming Chai, Bin Dong
Summary: Researchers have reported a metal-rich heterostructure of iron phosphide material that exhibits high efficiency in catalyzing hydrogen evolution. The material is synthesized through a hydrothermal method and phosphorization process. The results show that the metal-rich structure increases the active sites and the successful doping of metallic silver improves the conductivity and stability of the electrocatalyst.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2022)
Article
Biochemical Research Methods
Jingwen Li, Penghui Liang, Tianyu Zhao, Gengchen Guo, Jinyue Zhu, Congying Wen, Jingbin Zeng
Summary: In this study, a novel magnetic-Raman-colorimetric nanoparticle was developed for highly sensitive detection of SARS-CoV-2 nucleocapsid protein antibodies. The method exhibited high accuracy, sensitivity, and reproducibility, and could differentiate different serum samples. This approach is valuable for evaluating disease processes and guiding treatment.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Ying Wang, Jingwen Li, Hongyu Liu, Xu Du, Limin Yang, Jingbin Zeng
Summary: Developed a sensor array with colorimetric and photothermal modes for the identification of multiple pathogenic bacteria. This array based on functionalized nanoparticles can differentiate each bacterium using linear discriminant analysis and show better differentiation compared to other sensing arrays. It can not only distinguish different bacteria but also perform preliminary discrimination of unknown samples.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Physical
Honglin Li, Shoufu Cao, Hongman Sun, Yonglian Lu, Ying Zhang, Xiaoqing Lu, Jingbin Zeng, Zifeng Yan
Summary: In this study, Cu-based/CxNy catalysts were fabricated to improve the selectivity of C2H4 in CO2RR, overcoming the selectivity and stability issues of Cu catalyst. The precise tailoring of the synergistic effect between different Cu species and carbon nitride hybrids enabled the precise control of the product selectivity.
APPLIED CATALYSIS B-ENVIRONMENTAL
(2023)
Article
Chemistry, Physical
Ruyue Yu, Yanxue Shang, Xue Zhang, Jianting Liu, Fangdou Zhang, Xu Du, Hongman Sun, Jingbin Zeng
Summary: Compared to UV-driven catalysts, the use of sunlight to design efficient visible light catalysts has been less explored. In this study, Fe3O4@ZnO@ZIF-8 three-component core-shell nanoparticles were prepared and their photocatalytic degradation performance was investigated under visible light using Rhodamine B (RhB) as a model contaminant. It was found that Fe3O4@ZnO@ZIF-8 achieved a significant enhancement in the photo-catalytic degradation efficiency with 98% of RhB degraded within 100 min, and a reaction rate constant of 0.0292 min-1. These findings highlight the importance of precise tailoring of core-shell Fe3O4@ZnO@ZIF-8 for achieving desired degradation efficiency of organic pollutants under visible light.
CATALYSIS COMMUNICATIONS
(2023)
Article
Chemistry, Analytical
Cong-Ying Wen, Ling-Jin Zhao, Ying Wang, Kun Wang, Hui-Wen Li, Xiang Li, Min Zi, Jing-Bin Zeng
Summary: Au-Fe3O4 multifunctional nanoparticles were synthesized and integrated with lateral flow immunoassay for dual-mode detection of Salmonella typhimurium. The nanoparticles combined excellent local surface plasmon resonance characteristics, superparamagnetic properties, and good photothermal effect. The magnetic separation achieved the enrichment and purification of target bacteria, enhancing the detection sensitivity and reducing interference.
Article
Chemistry, Physical
Fan Feng, Zeping Ou, Fangdou Zhang, Jinxing Chen, Jiankun Huang, Jingxiang Wang, Haiqiang Zuo, Jingbin Zeng
Summary: This study incorporated deep machine learning into colorimetry by introducing a convolutional neural network (CNN), which improved the deficiencies of quantitative determination, susceptibility to ambient illuminance, and low sensitivity and visual resolution to tiny color changes. The proposed method was validated using a plasmonic nanosensor, and the results showed a satisfactory correlation (87.6%) with the standard blood glucose test method. The CNN was compiled as an application and implanted into an Android smartphone for practical use.
Article
Chemistry, Analytical
Tianyu Zhao, Penghui Liang, Jiaqi Ren, Jinyue Zhu, Xianning Yang, Hongyu Bian, Jingwen Li, Xiaofeng Cui, Chunhui Fu, Jinyan Xing, Congying Wen, Jingbin Zeng
Summary: A tri-mode lateral flow immunoassay (LFIA) platform based on gold-silver alloy hollow nanoshells (Au-Ag HNSs) was developed for the sensitive and accurate quantification of neutralizing antibodies, which are essential for assessing the effectiveness of vaccines.
ANALYTICA CHIMICA ACTA
(2023)
Article
Biophysics
Wei Duan, Jinling Wang, Xiaomeng Peng, Shoufu Cao, Jingjing Shang, Zhiwei Qiu, Xiaoqing Lu, Jingbin Zeng
Summary: We have designed a hydrophilic AgPt-Fe3O4 nanozyme with a unique heterodimeric nanostructure for CO sensing. The nanozyme is highly susceptible to CO poisoning due to the adequate exposure of active metallic sites and efficient interfacial synergy. We have developed a colorimetric strategy for CO detection with a low detection limit of 5.6 ppb.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Energy & Fuels
Zixiao Liu, Yonglian Lu, Chunfen Wang, Yu Zhang, Xiaodie Jin, Junwei Wu, Youhe Wang, Jingbin Zeng, Zifeng Yan, Hongman Sun, Chunfei Wu
Summary: In this study, three calcium-based metal frameworks were used as precursors to obtain nano CaO through a two-step thermal transition process, and it achieved a fast adsorption capacity of 11.8 mmol g-1. The improvement in cyclic performance was attributed to the gradual transformation of the precursor structure into nanosheets, preventing further aggregation of CaO particles during thermal transition. Pore structure was found to have little influence on the adsorption performance, suggesting that high stability can be achieved by avoiding particle sintering. This study highlights the importance of precise tailoring of nano-CaO for CO2 fast adsorption.
Article
Chemistry, Analytical
Cong-Ying Wen, Xinyi Liang, Jianting Liu, Tian -Yu Zhao, Xiang Li, Yu Zhang, Gengchen Guo, Zhuoran Zhang, Jingbin Zeng
Summary: By combining magnetic separation and three types of plasmonic nanoparticles, we have developed an achromatic nanosensor that can simultaneously detect SARS-CoV-2, Staphylococcus aureus, and Salmonella typhimurium. This colorless sensor enables convenient detection of multiple pathogens by observing color changes or measuring absorption spectra.
Correction
Biochemical Research Methods
Yong Wang, Suhua Yu, Rui Li, Jing Wan, Yuheng Wang, Zongli Huo, Chunyong Wu, Li Mi, Songqin Liu
JOURNAL OF CHROMATOGRAPHY A
(2024)
Review
Biochemical Research Methods
Israel D. Souza, Maria Eugenia C. Queiroz
Summary: Organic-silica hybrid monolithic materials have gained significant attention in separation science and sample preparation due to their unique properties. This review summarizes the characteristics, current status, and recent developments of these materials, as well as discusses synthesis methods, characterization techniques, and strategies for improving extraction efficiency in various applications.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Bhagwat Upreti, Bhanu Prasad Vempatapu, Jagdish Kumar, Pankaj K. Kanaujia
Summary: Lubricating oils are essential for the effective performance of internal combustion engines. This study presents a new HPLC method for determining additives in finished lubricating oils and polar substances in used engine oils.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zongqing Huang, Haoju Hua, Xiuzhen Du, Zipeng Zhen, Wei Zhao, Jun Feng, Ji-an Li
Summary: This study successfully isolated VHHs against the SUMO protein for the first time using biopanning of an immune camelid nanobody library. The VHHs were coupled to agarose resins to form affinity chromatography resins, allowing for one-step purification of various SUMO fusions.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Xueting Qiu, Xuben Hou, Yue Yang, Hao Fang, Fei Cui, Xinying Yang
Summary: In this study, a new method based on electrophoretically mediated microanalysis was developed for the investigation of PTPRO enzymatic activity. The method was successfully used to determine the kinetics of PTPRO and the inhibitory concentration of PTPRO inhibitors. The method exhibited improved accuracy and reduced consumption compared to traditional methods.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Feifei Luo, Mengmeng Hao, Lei Zhang, Yangguo Xie, Wei Hou, Hongya Wang, Zhongli Zhang
Summary: In this study, a comprehensive screening and structure elucidation of 23 nonvolatile organic compounds (NVOCs) in two antibody drugs was conducted. Seven previously unreported compounds were identified. A quantitative method with high sensitivity, accuracy, and precision was developed for evaluating the safety of NVOCs in drug products.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zuzana Vosahlova, Kveta Kalfkova, Martin Gilar, Jakub Szymarek, Maria Mazurkiewicz-Beldzinska, Sylwia Studzi
Summary: A hydrophilic interaction liquid chromatography method was developed for the separation and identification of oligonucleotide impurities and metabolites, and successfully applied to the analysis of serum samples from Spinraza-treated patients.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Aswanidevi Kongasseri, Thirumalai Madhesan, Sangeetha Krishna Kumar, Sushmitha Pedugu Sivaraman, Suchashrita Mitra, Pitchaiah Kancharlapalli Chinaraga, C. V. S. Brahmmananda Rao, Sivaraman Nagarajan, Prabhakaran Deivasigamani, Akhila Maheswari Mohan
Summary: This study focuses on the sequential separation of trivalent lanthanides using modified C-18 silica-packed supports and reversed-phase HPLC technique. By tuning the column modifiers and separation parameters, the researchers achieved systematic separation of Ln(3+). The results showed that the choice of column modifiers and fine-tuning of the modification procedure were crucial for achieving excellent separation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Raquel Perez-Robles, Szabolcs Fekete, Robert Kormany, Natalia Navas, Davy Guillarme
Summary: There is a mismatch between the sample diluent and the mobile phase in HILIC analysis, leading to analyte breakthrough and peak distortion. Adding a weak solvent for pre-injection can effectively prevent these issues and improve sensitivity.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oleg Pokrovskiy, Irina Rostovschikova, Konstantin Ustinovich, Ilya Voronov, Dmitry Kosyakov
Summary: A chromatography-like propagation of water through the material bed was observed during supercritical fluid extraction of aroma plants with high moisture content, which could be significant for modeling the kinetics of supercritical fluid extraction of non-volatile compounds.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Yasar Kemal Recepoglu, Ozguer Arar, Asli Yuksel
Summary: Biosorption using phosphorylated hazelnut shell waste (FHS) is a promising method for lithium removal and recovery. This study investigated the performance of a continuous-flow packed-bed column system using FHS for ultra-low level lithium removal. The results showed that the lihium biosorption capacity of the FHS column was unaffected by the bed height, but decreased with increasing flow rate.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Jian Sun, Zheheng Zheng, Zixiao Jia, Jiabin Wang, Xucong Lin
Summary: In this study, an ionic covalent organic framework (iCOF) surface grafting monolithic sorbent was prepared for in-tube solid-phase microextraction (SPME) of aristolochic acids (AAs) in various samples. The density of quaternary ammonium ions in the iCOF was modulated for enhanced adsorption of AAs. The iCOF surface grafting monolithic sorbent was confirmed by different means. Several operating conditions were optimized to develop the online in-tube SPME-HPLC method, which showed good linearity, low limits of detection, and high recoveries for AAs in serum samples. This study presents a feasible approach for the application of COF-based monolithic sorbents in sample preparation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zeng Wen, Ruihan Peng, Die Gao, Jing Lin, Jia Zeng, Zhou Li, Famin Ke, Zhining Xia, Dandan Wang
Summary: A chitosan-alginate sponge with multiple cross-linking networks was developed for adsorption and enrichment of anionic dyes from food samples. The sponge showed better three-dimensional network structure, mechanical behavior, and stability compared to pure chitosan and alginate sponges. The adsorption performance and selectivity of the sponge were systematically studied, and it maintained high adsorption capacity and selectivity for anionic dyes. The sponge also showed satisfactory reusability and was successfully combined with high-performance liquid chromatography for the enrichment and detection of anionic dyes in candy and cocktail samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Hairong Zhang, Xiaojuan Jiang, Dandan Zhang, Yuexin Yang, Qiang Xie, Caisheng Wu
Summary: Analysis of in vivo exposure to traditional Chinese medicine using mass spectrometry is helpful for identifying effective ingredients and developing new drugs. This study focused on Forsythia suspensa (Lian Qiao) and used metabolomics technology to explore its in vivo exposure. By comparing the differences before and after administration, a complete set of nontargeted analysis strategies for TCM exposure was established. The study identified 393 Lian Qiao-related chemical components in mice after administration, including prototypes and metabolites. This study provides a reference for research on the active ingredients of Lian Qiao in vivo.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oscar Castejon-Musulen, Ricardo Lopez, Ignacio Ontan, Vicente Ferreira
Summary: A quantitative analytical method was developed and validated in this study to determine the concentrations of 81 aroma-relevant wine volatiles. The method utilizes stir bar sorptive extraction and multidimensional gas chromatography with flame ionization detector or mass spectrometer. The method demonstrated good linearity, reproducibility, and recovery, and was successfully applied to analyze 20 wine samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)
