Journal
JOURNAL OF CHROMATOGRAPHY A
Volume 1269, Issue -, Pages 178-188Publisher
ELSEVIER
DOI: 10.1016/j.chroma.2012.09.071
Keywords
Immobilized polysaccharide-based chiral stationary phases; Enantiomer resolution by HPLC; Complementary properties; Mobile phase effect; Sample solvent effect; Additive effect
Ask authors/readers for more resources
The immobilized polysaccharide-derived chiral stationary phases (CSPs) combine the benefits of broad application scope and high preparative potential with CSP robustness and universal solvent compatibility. Strategies for efficient and straightforward method development with these CSPs were previously overviewed. In the current study, six CSPs with different structural features in the immobilized series were examined for their complementary properties in separation of enantiomers. Some method development aspects related to polysaccharide-derived CSPs in general and certain specific features observed on these immobilized supports, such as the effects of mobile phase, sample solvent and mobile phase additive on chiral separation, are also discussed. (C) 2012 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available