Tissue-Plasminogen Activator Attenuates Alzheimer’s Disease-Related Pathology Development in APPswe/PS1 Mice

The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation

(2016) Anja Henn   ALTEX-Alternatives to Animal Experimentation

Migration of Bone Marrow-Derived Cells Into the Central Nervous System in Models of Neurodegeneration

(2015) Antoine Lampron et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Tissue plasminogen activator arrests Alzheimer's disease pathogenesis

(2013) Shin Bi Oh et al.   NEUROBIOLOGY OF AGING

Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta

(2013) Ana Griciuc et al.   NEURON

Real-Time In Vivo Imaging Reveals the Ability of Monocytes to Clear Vascular Amyloid Beta

(2013) Jean-Philippe Michaud et al.   Cell Reports

Mild chronic cerebral hypoperfusion induces neurovascular dysfunction, triggering peripheral beta-amyloid brain entry and aggregation

(2013) Ayman ElAli et al.   Acta Neuropathologica Communications

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE

Age-related changes in synaptic markers and monocyte subsets link the cognitive decline of APPSwe/PS1 mice

(2012) Gaëlle Naert et al.   Frontiers in Cellular Neuroscience

Liver X Receptor Activation Enhances Blood-Brain Barrier Integrity in the Ischemic Brain and Increases the Abundance of ATP-Binding Cassette Transporters ABCB1 and ABCC1 on Brain Capillary Cells

(2011) Ayman ElAli et al.   BRAIN PATHOLOGY

Activation of JNK Signaling Mediates Amyloid-ß-Dependent Cell Death

(2011) Meghana Tare et al.   PLoS One

Matrix Metalloproteinase 2 (MMP-2) Degrades Soluble Vasculotropic Amyloid-β E22Q and L34V Mutants, Delaying Their Toxicity for Human Brain Microvascular Endothelial Cells

(2010) Mar Hernandez-Guillamon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Apolipoprotein E Controls ATP-Binding Cassette Transporters in the Ischemic Brain

(2010) A. ElAli et al.   Science Signaling

Powerful beneficial effects of macrophage colony-stimulating factor on  -amyloid deposition and cognitive impairment in Alzheimer's disease

(2009) V. Boissonneault et al.   BRAIN

Age-related cognitive decline and nesting behavior in an APPswe/PS1 bigenic model of Alzheimer's disease

(2009) Mohammed Filali et al.   BRAIN RESEARCH

Clearance of Amyloid-β Peptide Across the Blood-Brain Barrier: Implication for Therapies in Alzheimers Disease

(2009) R. Deane et al.   CNS & Neurological Disorders-Drug Targets

Tissue Plasminogen Activator (tPA) and Matrix Metalloproteinases in the Pathogenesis of Stroke: Therapeutic Strategies

(2008) Rao Adibhatla et al.   CNS & Neurological Disorders-Drug Targets

Mechanisms of Microglia-Mediated Neurotoxicity in a New Model of the Stroke Penumbra

(2008) V. Kaushal et al.   JOURNAL OF NEUROSCIENCE

Microglial Dysfunction and Defective  -Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice

(2008) S. E. Hickman et al.   JOURNAL OF NEUROSCIENCE