Differential Effects of an NR2B NAM and Ketamine on Synaptic Potentiation and Gamma Synchrony: Relevance to Rapid-Onset Antidepressant Efficacy

Application of neurophysiological biomarkers for Huntington's disease: Evaluating a phosphodiesterase 9A inhibitor

(2015) Dávid Nagy et al.   EXPERIMENTAL NEUROLOGY

Enhancing ketamine translational pharmacology via receptor occupancy normalization

(2014) Christopher L. Shaffer et al.   NEUROPHARMACOLOGY

A systematic review and meta-analysis of randomized, double-blind, placebo-controlled trials of ketamine in the rapid treatment of major depressive episodes

(2014) A. McGirr et al.   PSYCHOLOGICAL MEDICINE

NR2B Antagonist CP-101,606 Abolishes Pitch-Mediated Deviance Detection in Awake Rats

(2014) Digavalli V. Sivarao et al.   Frontiers in Psychiatry

Rapid-Acting Glutamatergic Antidepressants: The Path to Ketamine and Beyond

(2013) John H. Krystal et al.   BIOLOGICAL PSYCHIATRY

Impact of Ketamine on Neuronal Network Dynamics: Translational Modeling of Schizophrenia-Relevant Deficits

(2013) Bernat Kocsis et al.   CNS Neuroscience & Therapeutics

Lanicemine: a low-trapping NMDA channel blocker produces sustained antidepressant efficacy with minimal psychotomimetic adverse effects

(2013) G Sanacora et al.   MOLECULAR PSYCHIATRY

NMDA Receptors Subserve Persistent Neuronal Firing during Working Memory in Dorsolateral Prefrontal Cortex

(2013) Min Wang et al.   NEURON

Neurophysiological signals as potential translatable biomarkers for modulation of metabotropic glutamate 5 receptors

(2013) B.D. Harvey et al.   NEUROPHARMACOLOGY

Sub-Anesthetic Ketamine Modulates Intrinsic BOLD Connectivity Within the Hippocampal-Prefrontal Circuit in the Rat

(2013) Natalia Gass et al.   NEUROPSYCHOPHARMACOLOGY

Rhythmic theta and delta activity of cortical and hippocampal neuronal networks in genetically or pharmacologically induced N-methyl-d-aspartate receptor hypofunction under urethane anesthesia

(2013) T. Kiss et al.   NEUROSCIENCE

Synaptic Potentiation Is Critical for Rapid Antidepressant Response to Ketamine in Treatment-Resistant Major Depression

(2012) Brian R. Cornwell et al.   BIOLOGICAL PSYCHIATRY

NMDAR antagonist action in thalamus imposes delta oscillations on the hippocampus

(2012) Yuchun Zhang et al.   JOURNAL OF NEUROPHYSIOLOGY

Has an Angel Shown the Way? Etiological and Therapeutic Implications of the PCP/NMDA Model of Schizophrenia

(2012) D. C. Javitt et al.   SCHIZOPHRENIA BULLETIN

Capturing the Angel in "Angel Dust": Twenty Years of Translational Neuroscience Studies of NMDA Receptor Antagonists in Animals and Humans

(2012) B. Moghaddam et al.   SCHIZOPHRENIA BULLETIN

State-Dependent Increase of Cortical Gamma Activity during REM Sleep after Selective Blockade of NR2B Subunit Containing NMDA Receptors

(2012) Bernat Kocsis   SLEEP

Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure

(2011) Nanxin Li et al.   BIOLOGICAL PSYCHIATRY

Differential Role of NR2A and NR2B Subunits in N-Methyl-D-Aspartate Receptor Antagonist-Induced Aberrant Cortical Gamma Oscillations

(2011) Bernat Kocsis   BIOLOGICAL PSYCHIATRY

Comparison of the effects of acute and chronic administration of ketamine on hippocampal oscillations: relevance for the NMDA receptor hypofunction model of schizophrenia

(2011) Kara Kittelberger et al.   Brain Structure & Function

Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors

(2011) Erkan Karakas et al.   NATURE

Comparative analysis of the neurophysiological profile of group II metabotropic glutamate receptor activators and diazepam: Effects on hippocampal and cortical EEG patterns in rats

(2011) Chester J. Siok et al.   NEUROPHARMACOLOGY

NMDA receptors, cognition and schizophrenia – Testing the validity of the NMDA receptor hypofunction hypothesis

(2011) Gary Gilmour et al.   NEUROPHARMACOLOGY

Delta oscillations induced by ketamine increase energy levels in sleep-wake related brain regions

(2011) M. Dworak et al.   NEUROSCIENCE

A comparison of the effects of ketamine and phencyclidine with other antagonists of the NMDA receptor in rodent assays of attention and working memory

(2011) Janice W. Smith et al.   PSYCHOPHARMACOLOGY

Translating Glutamate: From Pathophysiology to Treatment

(2011) D. C. Javitt et al.   Science Translational Medicine

Delta oscillation and short-term plasticity in the rat medial prefrontal cortex: modelling NMDA hypofunction of schizophrenia

(2010) Tamás Kiss et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

(2010) S. F. Traynelis et al.   PHARMACOLOGICAL REVIEWS

A within-subject cognitive battery in the rat: differential effects of NMDA receptor antagonists

(2010) Sophie Dix et al.   PSYCHOPHARMACOLOGY

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

Gamma and Delta Neural Oscillations and Association with Clinical Symptoms under Subanesthetic Ketamine

(2009) L Elliot Hong et al.   NEUROPSYCHOPHARMACOLOGY

Activation of Cannabinoid-1 Receptors Disrupts Sensory Gating and Neuronal Oscillation: Relevance to Schizophrenia

(2008) Mihály Hajós et al.   BIOLOGICAL PSYCHIATRY

Differential effects of ageing on the EEG during pentobarbital and ketamine anaesthesia

(2008) Y. Fu et al.   EUROPEAN JOURNAL OF ANAESTHESIOLOGY

An Innovative Design to Establish Proof of Concept of the Antidepressant Effects of the NR2B Subunit Selective N-Methyl-D-Aspartate Antagonist, CP-101,606, in Patients With Treatment-Refractory Major Depressive Disorder

(2008) Sheldon H. Preskorn et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Effects of a NR2B selective NMDA glutamate antagonist, CP-101,606, on dyskinesia and parkinsonism

(2008) John G. Nutt et al.   MOVEMENT DISORDERS

N-Methyl d-Aspartate Receptor Antagonists Ketamine and MK-801 Induce Wake-Related Aberrant γ Oscillations in the Rat Neocortex

(2007) Didier Pinault   BIOLOGICAL PSYCHIATRY

Neurophysiological biomarkers for drug development in schizophrenia

(2007) Daniel C. Javitt et al.   NATURE REVIEWS DRUG DISCOVERY