Article
Business
David H. Weng, Yasuhiro Yamakawa
Summary: This study examines the impact of target venture CEO overconfidence on the outcomes of acquisitions. The findings show that overconfident CEOs can negatively affect the negotiation and integration processes, leading to a lower likelihood of successful acquisitions.
SMALL BUSINESS ECONOMICS
(2023)
Article
Green & Sustainable Science & Technology
Christoph Kerner, Thomas Brudermann
Summary: Voluntary carbon offsets (VCO) have been introduced as a means of compensating personal carbon emissions related to traveling. Despite low purchases in the past, increasing awareness of climate change may lead to future growth. VCO may not only offset emissions but also help eco-minded individuals alleviate flight shame.
Review
Behavioral Sciences
Angel Carvajal-Oliveros, Jorge M. Campusano
Summary: Serotonin functions as a neurotransmitter in the brain, regulating complex behaviors and neurodevelopment, with early alterations in its signaling linked to various neurodevelopmental disorders. Animal models may provide valuable insights into the complexity of serotonin actions and its role in brain disorders.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
(2021)
Article
Cell Biology
Anjaneyulu Murari, Shauna-Kay Rhooms, Divya Vimal, Kaniz Fatima Binte Hossain, Sanjay Saini, Maximino Villanueva, Michael Schlame, Edward Owusu-Ansah
Summary: The function of phospholipids intertwined with mitochondrial complex I subunits in the membrane domain of CI is unclear. However, disrupted PL transporter STARD7 impairs assembly of OXPHOS system and CI subcomplexes, while restrained knockdown of STARD7 affects incorporation of NDUFS5 and NDUFA1 into the proximal part of CI membrane domain. The knockdown also induces modest cardio-lipin remodeling, indicating alteration in mitochondrial phospholipid composition.
Article
Genetics & Heredity
Eiji Inoue, Takahiro Suzuki, Yasuharu Shimizu, Keiichi Sudo, Haruhisa Kawasaki, Norio Ishida
Summary: Saffron and its constituent crocetin have been found to inhibit the progression of PD in animal models, showing effects such as improving climbing ability, extending lifespan, and providing cytoprotection.
Article
Fisheries
Soraya Pieroni, Bruno Silva Olier, Isabela Ramos Lima, Isadora Marini Sanches, Vanessa Villanova Kuhnen, Eduardo Gomes Sanches
Summary: This study evaluated the influence of different substrates on water quality and the development of lambari fish and freshwater shrimp. It was found that dolomite and shell gravel affected the parameters related to the acid-base balance of the water and the availability of calcium and magnesium. The productive performance of lambari fish was not affected by the different substrates, but freshwater shrimp showed lower productivity in the absence of substrates.
AQUACULTURE INTERNATIONAL
(2021)
Review
Biotechnology & Applied Microbiology
Tulio L. Campos, Pasi K. Korhonen, Andreas Hofmann, Robin B. Gasser, Neil D. Young
Summary: The development of high-quality genomes and advances in functional genomics have led to the need for innovative techniques for predicting and investigating essential genes. Machine learning approaches offer the potential to reliably predict gene importance and could be a valuable tool for biological research.
BIOTECHNOLOGY ADVANCES
(2022)
Article
Parasitology
Collin J. Horn, Caroline Liang, Lien T. Luong
Summary: Body size is generally correlated with insect fitness and can also be related to the abundance of parasites. The preferences of parasites and variation in host immunity may contribute to this trend. In this study, we investigated the impact of host size on mite-fly interactions, finding that mites showed a strong preference for infecting larger flies and larger flies were more susceptible to infection and acquired more mites. These preferences of parasites resulted in a biased infection outcome based on host size. The implications of this heterogeneity on parasite overdispersion and fly populations are discussed.
INTERNATIONAL JOURNAL FOR PARASITOLOGY
(2023)
Article
Religion
Sandra Menssen, Thomas D. Sullivan
Summary: This article is directed towards agnostics who find some specific revelatory claim more plausible than theistic competitors and argues that they have an obligation to assent to the claim if it offers a means for remediation of wrong-doing. The focus is on the Christian revelatory claim, but the argument's template can be applied to other religions that promise to fix the world's problems in an afterlife.
Article
Multidisciplinary Sciences
Stephen Boyd Davis, Olivia Vane, Florian Kraeutli
Summary: The authors delve into the increasing importance of trust issues in relation to data and its use, focusing on humanities data and its visualization through analysis of recent projects with museums, archives, and libraries internationally. They discuss potential sources of mistrust and how different expectations and assumptions vary depending on the use and user of the data, offering a simple schema to trace implications. The article argues that vital trust issues can be addressed through design, which is seen as contributing insights and questions that impact the entire process.
INTERDISCIPLINARY SCIENCE REVIEWS
(2021)
Review
Entomology
Zi-Jing Zhang, Hao Zheng
Summary: Eusocial bumble and honey bees play a vital role in global ecology and agriculture, but differ in morphology, physiology, behavior, and life cycle despite similar host-restricted gut microbiota. Bumblebee gut bacteria show less functional capacity for carbohydrate metabolism compared to honeybees. The unique life cycle of bumblebees affects the diversity of their gut bacteria and may provide valuable insights into host-microbe interactions, gut-brain axis, and vertical transmission.
Article
Cell Biology
Keith C. Cheng, Rebecca D. Burdine, Mary E. Dickinson, Stephen C. Ekker, Alex Y. Lin, K. C. Kent Lloyd, Cathleen M. Lutz, Calum A. MacRae, John H. Morrison, David H. O'Connor, John H. Postlethwait, Crystal D. Rogers, Susan Sanchez, Julie H. Simpson, William S. Talbot, Douglas C. Wallace, Jill M. Weimer, Hugo J. Bellen
Summary: Model organism research is important for understanding biology and disease, as the molecular and cellular language of life is evolutionarily conserved. It is used to study gene function, develop techniques, and test drug efficacy. To maximize the value of model organisms, there is a need for improved rigor, validation, reproducibility, and translatability in research.
DISEASE MODELS & MECHANISMS
(2022)
Article
Multidisciplinary Sciences
Leticia Leandro Batista, Serena Mares Malta, Heitor Cappato Guerra Silva, Luiza Diniz Ferreira Borges, Lays Oliveira Rocha, Jessica Regina da Silva, Tamiris Sabrina Rodrigues, Gabriela Venturini, Kallyandra Padilha, Alexandre da Costa Pereira, Foued Salmen Espindola, Carlos Ueira-Vieira
Summary: Dysbiosis is an important factor in Alzheimer's disease, and probiotics such as kefir have shown to be a promising therapeutic alternative for the disease.
SCIENTIFIC REPORTS
(2021)
Article
Computer Science, Artificial Intelligence
Lun Li, Zhuhong Zhang, Wensheng Jia, Jiaxuan Lu
Summary: This study develops an artificial fly visual brain neural network with presynaptic and postsynaptic subnetworks to detect changes in visual motion in panoramic scenes. The network collects excitatory intensities of visual neurons and outputs real-time activities of the main object closest to the panoramic camera. The computational model successfully performs omnidirectional collision detection and exhibits motion characteristics of the main object in the panoramic environment.
INTERNATIONAL JOURNAL OF INTELLIGENT SYSTEMS
(2023)
Article
Cell & Tissue Engineering
Janak Gaire, Justin A. Varholick, Sabhya Rana, Michael D. Sunshine, Sylvain Dore, W. Brad Barbazuk, David D. Fuller, Malcolm Maden, Chelsey S. Simmons
Summary: The spiny mouse is an exciting research organism due to its remarkable scarless healing abilities in various tissues beyond the skin, which could shed light on numerous clinically relevant human diseases. However, there are challenges in working with this emerging research organism that require future strategies and methods.
NPJ REGENERATIVE MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
D. A. Gonzalez, T. Jia, J. H. Pinzon, S. F. Acevedo, S. A. Ojelade, B. Xu, N. Tay, S. Desrivieres, J. L. Hernandez, T. Banaschewski, C. Buechel, A. L. W. Bokde, P. J. Conrod, H. Flor, V. Frouin, J. Gallinat, H. Garavan, P. A. Gowland, A. Heinz, B. Ittermann, M. Lathrop, J-L Martinot, T. Paus, M. N. Smolka, A. R. Rodan, G. Schumann, A. Rothenfluh
MOLECULAR PSYCHIATRY
(2018)
Article
Multidisciplinary Sciences
Nevine A. Shalaby, Jorge H. Pinzon, Anjana S. Narayanan, Eugene Jennifer Jin, Morgan P. Ritz, Rachel J. Dove, Heike Wolfenberg, Aylin R. Rodan, Michael Buszczak, Adrian Rothenfluh
SCIENTIFIC REPORTS
(2018)
Article
Multidisciplinary Sciences
Nevine A. Shalaby, Raheel Sayed, Qiao Zhang, Shane Scoggin, Susan Eliazer, Adrian Rothenfluh, Michael Buszczak
SCIENTIFIC REPORTS
(2017)
Article
Psychology, Biological
Evangelos Evangelou, He Gao, Congying Chu, Georgios Ntritsos, Paul Blakeley, Andrew R. Butts, Raha Pazoki, Hideaki Suzuki, Fotios Koskeridis, Andrianos M. Yiorkas, Ibrahim Karaman, Joshua Elliott, Qiang Luo, Stefanie Aeschbacher, Traci M. Bartz, Sebastian E. Baumeister, Peter S. Braund, Michael R. Brown, Jennifer A. Brody, Toni-Kim Clarke, Niki Dimou, Jessica D. Faul, Georg Homuth, Anne U. Jackson, Katherine A. Kentistou, Peter K. Joshi, Rozenn N. Lemaitre, Penelope A. Lind, Leo-Pekka Lyytikainen, Massimo Mangino, Yuri Milaneschi, Christopher P. Nelson, Ilja M. Nolte, Mia-Maria Perala, Ozren Polasek, David Porteous, Scott M. Ratliff, Jennifer A. Smith, Alena Stancakova, Alexander Teumer, Samuli Tuominen, Sebastien Theriault, Jagadish Vangipurapu, John B. Whitfield, Alexis Wood, Jie Yao, Bing Yu, Wei Zhao, Dan E. Arking, Juha Auvinen, Chunyu Liu, Minna Mannikko, Lorenz Risch, Jerome Rotter, Harold Snieder, Juha Veijola, Alexandra Blakemore, Michael Boehnke, Harry Campbell, David Conen, Johan G. Eriksson, Hans J. Grabe, Xiuqing Guo, Pim van der Harst, Catharina A. Hartman, Caroline Hayward, Andrew C. Heath, Marjo-Riitta Jarvelin, Mika Kahonen, Sharon L. R. Kardia, Michael Kuhne, Johanna Kuusisto, Maru Laakso, Jari Lahti, Terho Lehtimaki, Andrew M. McIntosh, Karen L. Mohlke, Alanna C. Morrison, Nicholas G. Martin, Albertine J. Oldehinkel, Brenda W. J. H. Penninx, Bruce M. Psaty, T. Raitakari, Igor Rudan, Nilesh J. Samani, Laura J. Scott, Tim D. Spector, Niek Verweij, David R. Weir, James F. Wilson, Daniel Levy, Ioanna Tzoulaki, Jimmy D. Bell, Paul M. Matthews, Adrian Rothenfluh, Sylvane Desrivieres, Gunter Schumann, Paul Elliott
NATURE HUMAN BEHAVIOUR
(2019)
Article
Neurosciences
Andrew R. Butts, Shamsideen Ojelade, Eva D. Pronovost, Alexandra Seguin, Collin B. Merrill, Aylin R. Rodan, Adrian Rothenfluh
JOURNAL OF NEUROSCIENCE
(2019)
Review
Biochemistry & Molecular Biology
Daniel R. Lathen, Collin B. Merrill, Adrian Rothenfluh
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Review
Behavioral Sciences
Maggie M. Chvilicek, Iris Titos, Adrian Rothenfluh
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
(2020)
Article
Biology
Puskar Mishra, Shany E. Yang, Austin B. Montgomery, Addison R. Reed, Aylin R. Rodan, Adrian Rothenfluh
Summary: The study introduces a new assay, FLEA, to accurately measure incentive motivation in Drosophila by adjusting electrical current levels in each feeding well. It is found that external incentives and internal motivational state can drive flies to overcome higher currents for better food, and current perception is not discounted as the flies become more food-deprived. Additionally, it is demonstrated that neuropeptide F plays a role in sensory processing of electrical current in fruit flies.
Editorial Material
Multidisciplinary Sciences
Iris Titos, Adrian Rothenfluh
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Biochemistry & Molecular Biology
Travis James Philyaw, Adrian Rothenfluh, Iris Titos
Summary: This article introduces Drosophila as a translational model organism for studying the effects of psychostimulant drugs and discusses its efficiency and cost-effectiveness in discovering novel candidate genes and molecular mechanisms involved in behavioral responses.
Article
Biotechnology & Applied Microbiology
Collin B. Merrill, Austin B. Montgomery, Miguel A. Pabon, Andrey A. Shabalin, Aylin R. Rodan, Adrian Rothenfluh
Summary: This study applied ATAC-seq and RNA-seq to investigate chromatin regions and gene expression changes in response to insulin signaling pathway in Drosophila cells. The results showed correlations between accessible chromatin regions and gene expression, especially for enhancer regions. Cloning of candidate enhancer regions demonstrated the potential of insulin-inducible reporter gene expression.
Article
Biochemistry & Molecular Biology
Jeffrey N. Schellinger, Qifei Sun, John M. Pleinis, Sung-Wan An, Jianrui Hu, Gaelle Mercenne, Iris Titos, Chou-Long Huang, Adrian Rothenfluh, Aylin R. Rodan
Summary: The intracellular chloride concentration in the small ventral lateral (sLN(v)) pacemaker neurons of fruit flies can regulate the length of the circadian period by influencing the activation of the WNK-Fray signaling pathway and the activation of an inwardly rectifying potassium channel. This finding helps us understand the regulatory mechanism of circadian rhythms.
Article
Multidisciplinary Sciences
Collin B. Merrill, Miguel A. Pabon, Austin B. Montgomery, Aylin R. Rodan, Adrian Rothenfluh
Summary: ATAC-seq is a powerful method for studying gene regulation that is now being optimized for use in Drosophila, taking advantage of the unique features of this model system. The optimized protocol accounts for various complicating factors in flies and successfully generates high-quality libraries, paving the way for extensive studies on chromatin-mediated gene regulation in Drosophila.
SCIENTIFIC REPORTS
(2022)
Article
Substance Abuse
Jorge H. Pinzon, Addison R. Reed, Nevine A. Shalaby, Michael Buszczak, Aylin R. Rodan, Adrian Rothenfluh
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
(2017)
Review
Neurosciences
Karla R. Kaun, Adrian Rothenfluh
CURRENT OPINION IN NEUROBIOLOGY
(2017)
