Review
Chemistry, Analytical
Bin Hu, Gangfeng Ouyang
Summary: In situ sampling and analysis of human samples is crucial for understanding human physiological and pathological processes, and has been applied in various fields such as clinical diagnosis and environmental health. Strategies combining solid phase microextraction with mass spectrometry offer versatile methods for gaining insight into human health.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Thermodynamics
Shanjian Liu, An Zhao, Zhisen He, Yongjun Li, Dongmei Bi, Xin Gao
Summary: This study investigates the effects of urea concentration and pyrolysis temperature on the composition of bio-oil. The results demonstrate that nitrogen-rich pyrolysis increases the phenolic content, decreases the aldehyde and ketone content, and enhances the production of nitrogenous heterocyclic compounds.
Article
Chemistry, Multidisciplinary
Abdullah Alhendal, Randa Abd Almoaeen, Mohamed Rashad, Ali Husain, Fouzi Mouffouk, Zahoor Ahmad
Summary: This work presents a method for preparing an analytical microextraction sorbent using a sol-gel hybrid composite. The sorbent showed excellent repeatability, reproducibility, low LODs, and good affinity towards PAHs. It also demonstrated enhanced extraction capability compared to commercially available counterparts.
Article
Biochemical Research Methods
Yanyan Wang, Lili Lian, Xiyue Wang, Boying Yue, Lan Ding, Dawei Lou
Summary: In this study, velvet-like carbon nitride (V-g-C3N4) was prepared and modified on the surface of stainless-steel wire to obtain a solid-phase microextraction (SPME) coating for the extraction of polycyclic aromatic hydrocarbons (PAHs) from water samples. The method showed excellent performance in extraction efficiency and durability.
JOURNAL OF CHROMATOGRAPHY A
(2022)
Article
Engineering, Environmental
Xuemei Wang, Jie Zhang, Zhen Zhang, Jing Ru, Yuan Ma, Jingwei Liu, Xinzhen Du, Xiaoquan Lu
Summary: In this study, polystyrene grafted hollow layered double hydroxides (NiCo-LDH@PS) were prepared and used as solid-phase micro-extraction (SPME) coating for the rapid detection of polycyclic aromatic hydrocarbons (PAHs) in combination with high performance liquid chromatography (HPLC). The NiCo-LDH@PS-coated SPME fiber showed enhanced adsorption capacity for seven PAHs and required only a small amount of adsorbent. The study demonstrated the great application potential of the hollow core-shell structured NiCo-LDH@PS as an SPME composite coating in adsorption and separation field.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Chemistry, Analytical
Rasha S. Hanafi, Michael Laemmerhofer
Summary: This study proposes an advanced combined derivatization/solvent-less extraction procedure from plasma followed by rapid GC-MS detection. The sample pretreatment protocol based on aldehyde derivatization with methoxyamine under aqueous conditions followed by HS-SPME is faster compared to methods in the literature. The developed HS-SPME-GC-MS method was validated and applied for the targeted determination of lipid peroxidation aldehyde metabolites in plasma of cardiovascular patients. The concentrations of hexanal, malondialdehyde, and hydroxynonenal were significantly higher in patients, while citral was significantly lower.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Multidisciplinary
Muhammad Saqaf Jagirani, Furkan Uzcan, Mustafa Soylak
Summary: A SPME procedure using Cell-MNPs as adsorbent material was proposed for the extraction of trace amount of lead from environmental samples. The synthesized Cell-MNPs were characterized and various analytical parameters were optimized for the selective and sensitive extraction of lead (II). The method was successfully applied for the solid-phase extraction of lead (II) from water and tea samples.
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
(2021)
Article
Engineering, Chemical
Fangbing Wang, Xuemei Wang, Xinglan Cui, Hong Ji, Yacong Liu, Xinzhen Du, Xiaoquan Lu
Summary: A unique spiral solid phase microextraction fiber with HoMS-Co3O4/C coating was designed for capturing trace polycyclic aromatic hydrocarbons. The material had a unique hollow double-shelled structure derived from ZIF-67 ligand replacement and pyrolysis, showing higher selectivity for PAHs. The fiber demonstrated excellent enrichment ability, extraction efficiency, and successful detection of 15 PAHs in environmental water samples.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Dan Li, Mengyuan Li, Shiping Zhu, Yanmei Gao, Mengyao Mu, Ning Zhang, Youmei Wang, Minghua Lu
Summary: Sample pretreatment plays a vital role in the analysis and detection of trace pollutants. In this study, porous hexagonal boron nitride was used as a coating material for solid-phase microextraction, demonstrating excellent extraction performance for polycyclic aromatic hydrocarbons. The method was successfully applied to the analysis of real soil samples, with satisfactory results.
Article
Chemistry, Analytical
Qi Li, Fu Xiaoan, Kaiyi Xu, Haifeng He, Nan Jiang
Summary: The stability of carbonyl compounds in exhaled breath samples collected in Tedlar bags is essential for accurate quantification, with different storage conditions affecting recovery percentages.
MICROCHEMICAL JOURNAL
(2021)
Article
Environmental Sciences
Maral Selin Findikoglu Ercan, Merve Firat Ayyildiz, Elif Yazici, Berfin Metin, Dotse Selali Chormey, Elif Seda Kocoglu, Sezgin Bakirdere
Summary: Antarctica has seen an increase in scientific research and tourism, leading to potential contamination from anthropogenic activities. This study developed a sensitive method for determining polycyclic aromatic hydrocarbons in Antarctica using dispersive liquid-liquid microextraction. The method showed good performance and was successfully applied to samples collected from various sources in Antarctica.
ENVIRONMENTAL MONITORING AND ASSESSMENT
(2022)
Article
Chemistry, Analytical
Derek R. Eitzmann, Marcelino Varona, Jared L. Anderson
Summary: Nucleic acid analysis plays a crucial role in the COVID-19 global health crisis. This study develops a sample preparation method that reduces DNA isolation time and increases downstream analysis sensitivity. The functionalized planar supports modified with a polymeric ionic liquid sorbent coating show high DNA affinity, reproducibility, and reusability. The TFME devices achieve higher preconcentration factors and DNA recoveries compared to SPME devices, resulting in improved detection of SARS-CoV-2.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Serkan Sahan, Ugur Sahin, Monika Jakubus
Summary: This study developed and validated a UHPLC-DAD method for the determination of PAHs in sewage sludge and compost. The method showed good recovery values and precision for sample analysis.
ANALYTICAL LETTERS
(2023)
Article
Chemistry, Analytical
Du Jie, Sun Pengchao, Zhang Menglu, Lian Zete, Yuan Fenggang, Wang Gang
Summary: Polycyclic aromatic hydrocarbons (PAHs) are persistent organic pollutants that pose serious threats to the environment and human health. This study developed a new solid-phase microextraction (SPME) coating for the separation and enrichment of PAHs in environmental samples. The coating, prepared using an electrochemical method, exhibited good thermal stability and enrichment effects. An optimized analytical method with low detection limits and high stability was established for detecting PAHs in environmental water samples.
CHINESE JOURNAL OF CHROMATOGRAPHY
(2023)
Article
Chemistry, Analytical
Zhang Wenmin, Li Qingqing, Fang Min, Zhang Lan
Summary: A hollow bimetal-organic framework (H-BiMOF) was successfully synthesized and used for the trace extraction of PAHs from environmental samples. The H-BiMOF-coated SPME fiber showed advantages of quick equilibrium and high extraction efficiency. A new method for the determination of PAHs in environmental water samples was established by combining the H-BiMOF-coated SPME fiber with GC-MS/MS. The method exhibited low limits of detection, wide linear range, and good reproducibility, and was validated with real water samples.
CHINESE JOURNAL OF CHROMATOGRAPHY
(2022)
Article
Biophysics
Aparajita Singh, Syed Khalid Pasha, Pandiaraj Manickam, Shekhar Bhansali
BIOSENSORS & BIOELECTRONICS
(2016)
Review
Biophysics
Sohini RoyChoudhury, Vaishali Rawat, Ahmed Hasnain Jalal, S. N. Kale, Shekhar Bhansali
BIOSENSORS & BIOELECTRONICS
(2016)
Article
Electrochemistry
L. Burton, N. Dave, R. E. Fernandez, K. Jayachandran, S. Bhansali
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2018)
Article
Electrochemistry
Ahmed Hasnain Jalal, Yogeswaran Umasankar, Fraker Christopher, Ernesto A. Pretto, Shekhar Bhansali
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2018)
Article
Nanoscience & Nanotechnology
Apurva Sonawane, Mubarak A. Mujawar, Shekhar Bhansali
Article
Engineering, Electrical & Electronic
Apurva Sonawane, Mubarak A. Mujawar, Pandiaraj Manickam, Shekhar Bhansali
Summary: This study demonstrates the enhancement in distribution and improvement in electronic properties of gold nanoparticles through plasma-assisted technique for electrochemical sensing of cortisol. The plasma treatment induced size reduction and improved uniformity of particle distribution on electrode surface, increasing sensor sensitivity.
ACS APPLIED ELECTRONIC MATERIALS
(2021)
Review
Electrochemistry
M. Sekar, R. Sriramprabha, Praveen Kumar Sekhar, Shekhar Bhansali, N. Ponpandian, Manickam Pandiaraj, C. Viswanathan
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2020)
Review
Electrochemistry
Yemeserach Mekonnen, Srikanth Namuduri, Lamar Burton, Arif Sarwat, Shekhar Bhansali
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2019)
Article
Electrochemistry
Pulak Bhushan, Yogeswaran Umasankar, Sohini RoyChoudhury, Penelope A. Hirt, Flor E. MacQuhaec, Luis J. Borda, Hadar A. Lev-Tov, Robert S. Kirsner, Shekhar Bhansali
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2019)
Article
Electrochemistry
Sohini RoyChoudhury, Yogeswaran Umasankar, Pulak Bhushan, Penelope A. Hirt, Flor E. MacQuhae, Luis J. Borda, Hadar A. Lev-Tov, Robert Kirsner, Shekhar Bhansali
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2019)
Article
Electrochemistry
Akshaya Kumar, Naveen S. K. Kumar, Almaw Ayele Aniley, Renny Edwin Fernandez, Shekhar Bhansali
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2019)
Article
Electrochemistry
Apurva Sonawane, Mubarak A. Mujawar, Shekhar Bhansali
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2019)
Article
Electrochemistry
Almaw Ayele Aniley, Naveen S. K. Kumar, Akshaya A. Kumar, Renny Edwin Fernandez, Shekhar Bhansali
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2019)
Article
Biophysics
Ahmed Hasnain Jalal, Yogeswaran Umasankar, Pablo J. Gonzalez, Alejandro Alfonso, Shekhar Bhansali
BIOSENSORS & BIOELECTRONICS
(2017)
Proceedings Paper
Engineering, Electrical & Electronic
Yogeswaran Umasankar, Ahmed H. Jalal, Pablo J. Gonzalez, Mustahsin Chowdhury, Alejandro Alfonso, Shekhar Bhansali
2016 IEEE 13TH INTERNATIONAL CONFERENCE ON WEARABLE AND IMPLANTABLE BODY SENSOR NETWORKS (BSN)
(2016)
Correction
Biochemical Research Methods
Yong Wang, Suhua Yu, Rui Li, Jing Wan, Yuheng Wang, Zongli Huo, Chunyong Wu, Li Mi, Songqin Liu
JOURNAL OF CHROMATOGRAPHY A
(2024)
Review
Biochemical Research Methods
Israel D. Souza, Maria Eugenia C. Queiroz
Summary: Organic-silica hybrid monolithic materials have gained significant attention in separation science and sample preparation due to their unique properties. This review summarizes the characteristics, current status, and recent developments of these materials, as well as discusses synthesis methods, characterization techniques, and strategies for improving extraction efficiency in various applications.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Bhagwat Upreti, Bhanu Prasad Vempatapu, Jagdish Kumar, Pankaj K. Kanaujia
Summary: Lubricating oils are essential for the effective performance of internal combustion engines. This study presents a new HPLC method for determining additives in finished lubricating oils and polar substances in used engine oils.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zongqing Huang, Haoju Hua, Xiuzhen Du, Zipeng Zhen, Wei Zhao, Jun Feng, Ji-an Li
Summary: This study successfully isolated VHHs against the SUMO protein for the first time using biopanning of an immune camelid nanobody library. The VHHs were coupled to agarose resins to form affinity chromatography resins, allowing for one-step purification of various SUMO fusions.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Xueting Qiu, Xuben Hou, Yue Yang, Hao Fang, Fei Cui, Xinying Yang
Summary: In this study, a new method based on electrophoretically mediated microanalysis was developed for the investigation of PTPRO enzymatic activity. The method was successfully used to determine the kinetics of PTPRO and the inhibitory concentration of PTPRO inhibitors. The method exhibited improved accuracy and reduced consumption compared to traditional methods.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Feifei Luo, Mengmeng Hao, Lei Zhang, Yangguo Xie, Wei Hou, Hongya Wang, Zhongli Zhang
Summary: In this study, a comprehensive screening and structure elucidation of 23 nonvolatile organic compounds (NVOCs) in two antibody drugs was conducted. Seven previously unreported compounds were identified. A quantitative method with high sensitivity, accuracy, and precision was developed for evaluating the safety of NVOCs in drug products.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zuzana Vosahlova, Kveta Kalfkova, Martin Gilar, Jakub Szymarek, Maria Mazurkiewicz-Beldzinska, Sylwia Studzi
Summary: A hydrophilic interaction liquid chromatography method was developed for the separation and identification of oligonucleotide impurities and metabolites, and successfully applied to the analysis of serum samples from Spinraza-treated patients.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Aswanidevi Kongasseri, Thirumalai Madhesan, Sangeetha Krishna Kumar, Sushmitha Pedugu Sivaraman, Suchashrita Mitra, Pitchaiah Kancharlapalli Chinaraga, C. V. S. Brahmmananda Rao, Sivaraman Nagarajan, Prabhakaran Deivasigamani, Akhila Maheswari Mohan
Summary: This study focuses on the sequential separation of trivalent lanthanides using modified C-18 silica-packed supports and reversed-phase HPLC technique. By tuning the column modifiers and separation parameters, the researchers achieved systematic separation of Ln(3+). The results showed that the choice of column modifiers and fine-tuning of the modification procedure were crucial for achieving excellent separation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Raquel Perez-Robles, Szabolcs Fekete, Robert Kormany, Natalia Navas, Davy Guillarme
Summary: There is a mismatch between the sample diluent and the mobile phase in HILIC analysis, leading to analyte breakthrough and peak distortion. Adding a weak solvent for pre-injection can effectively prevent these issues and improve sensitivity.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oleg Pokrovskiy, Irina Rostovschikova, Konstantin Ustinovich, Ilya Voronov, Dmitry Kosyakov
Summary: A chromatography-like propagation of water through the material bed was observed during supercritical fluid extraction of aroma plants with high moisture content, which could be significant for modeling the kinetics of supercritical fluid extraction of non-volatile compounds.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Yasar Kemal Recepoglu, Ozguer Arar, Asli Yuksel
Summary: Biosorption using phosphorylated hazelnut shell waste (FHS) is a promising method for lithium removal and recovery. This study investigated the performance of a continuous-flow packed-bed column system using FHS for ultra-low level lithium removal. The results showed that the lihium biosorption capacity of the FHS column was unaffected by the bed height, but decreased with increasing flow rate.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Jian Sun, Zheheng Zheng, Zixiao Jia, Jiabin Wang, Xucong Lin
Summary: In this study, an ionic covalent organic framework (iCOF) surface grafting monolithic sorbent was prepared for in-tube solid-phase microextraction (SPME) of aristolochic acids (AAs) in various samples. The density of quaternary ammonium ions in the iCOF was modulated for enhanced adsorption of AAs. The iCOF surface grafting monolithic sorbent was confirmed by different means. Several operating conditions were optimized to develop the online in-tube SPME-HPLC method, which showed good linearity, low limits of detection, and high recoveries for AAs in serum samples. This study presents a feasible approach for the application of COF-based monolithic sorbents in sample preparation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zeng Wen, Ruihan Peng, Die Gao, Jing Lin, Jia Zeng, Zhou Li, Famin Ke, Zhining Xia, Dandan Wang
Summary: A chitosan-alginate sponge with multiple cross-linking networks was developed for adsorption and enrichment of anionic dyes from food samples. The sponge showed better three-dimensional network structure, mechanical behavior, and stability compared to pure chitosan and alginate sponges. The adsorption performance and selectivity of the sponge were systematically studied, and it maintained high adsorption capacity and selectivity for anionic dyes. The sponge also showed satisfactory reusability and was successfully combined with high-performance liquid chromatography for the enrichment and detection of anionic dyes in candy and cocktail samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Hairong Zhang, Xiaojuan Jiang, Dandan Zhang, Yuexin Yang, Qiang Xie, Caisheng Wu
Summary: Analysis of in vivo exposure to traditional Chinese medicine using mass spectrometry is helpful for identifying effective ingredients and developing new drugs. This study focused on Forsythia suspensa (Lian Qiao) and used metabolomics technology to explore its in vivo exposure. By comparing the differences before and after administration, a complete set of nontargeted analysis strategies for TCM exposure was established. The study identified 393 Lian Qiao-related chemical components in mice after administration, including prototypes and metabolites. This study provides a reference for research on the active ingredients of Lian Qiao in vivo.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oscar Castejon-Musulen, Ricardo Lopez, Ignacio Ontan, Vicente Ferreira
Summary: A quantitative analytical method was developed and validated in this study to determine the concentrations of 81 aroma-relevant wine volatiles. The method utilizes stir bar sorptive extraction and multidimensional gas chromatography with flame ionization detector or mass spectrometer. The method demonstrated good linearity, reproducibility, and recovery, and was successfully applied to analyze 20 wine samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)