Article
Chemistry, Applied
Jiaqing Feng, Juanjuan Feng, Herman Maloko Loussala, Sen Han, Xiangping Ji, Chunying Li, Haili Sun, Min Sun
Summary: Researchers have developed a dendritic mesoporous silica nanospheres@porous carbon material for the solid-phase microextraction of PAHs, which has characteristics such as high surface area, suitable pore sizes, and high carbon content. This material has been proven to be a potential extraction material for the detection of PAHs in tea beverages through online in-tube solid-phase microextraction.
Article
Chemistry, Analytical
Min Sun, Sen Han, Herman Maloko Loussala, Juanjuan Feng, Chunying Li, Xiangping Ji, Jiaqing Feng, Haili Sun
Summary: The study developed an online detection method for PAHs in honey using graphene oxide-functionalized mesoporous silica as the coating for in-tube solid phase microextraction, coupled with high performance liquid chromatography. The method exhibited a low detection limit and high enrichment effect for trace PAHs in honey after optimization.
MICROCHEMICAL JOURNAL
(2021)
Article
Environmental Sciences
Melissa M. M. Melough, Maricel V. J. Maffini, Jennifer J. Otten, Sheela Sathyanarayana
Summary: This study found no significant association between recommended healthy diets and exposure to endocrine-disrupting chemicals (EDCs). However, certain healthy diets may increase EDC exposures and related adverse health outcomes, particularly in relation to thyroid hormones.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Jaroslav Mosko, Michael Pohorely, Tomas Cajthaml, Michal Jeremias, Ana A. Robles-Aguilar, Siarhei Skoblia, Zdenek Beno, Petra Innemanova, Lucie Linhartova, Klara Michalikova, Erik Meers
Summary: The study focused on using slow pyrolysis to treat organic pollutants in stabilized sewage sludge, finding that temperatures above 600 degrees Celsius effectively removed the majority of organic pollutants. It was proposed that high temperature (>600 degrees Celsius) slow pyrolysis can satisfactorily remove organic pollutants from resulting sludge-char, making it a safe soil improver.
Article
Environmental Sciences
Paolo Cocci, Gilberto Mosconi, Francesco Alessandro Palermo
Summary: This study evaluated the accumulation patterns of polycyclic aromatic hydrocarbons (PAHs) in common cuttlefish and explored their effects on gene expression and developmental processes. The results showed that PAH levels were higher in egg capsules compared to chorion membranes, and PAHs were also found in perivitellin fluid. Embryos with high PAH concentrations exhibited increased expression of homeobox genes, particularly ARX. The upregulation of homeobox genes may be related to the activation of AhR and ER signaling pathways by PAHs.
Article
Endocrinology & Metabolism
Yun Sung Jo, Hyun Sun Ko, Ah Young Kim, Ha Gyeong Jo, Woo Jung Kim, Sae Kyung Choi
Summary: This study investigates the effects of polycyclic aromatic hydrocarbons (PAHs) on placental cells, revealing their negative impact on pregnancy, which was previously unknown. The findings can be used to identify harmful PAHs in pregnant women who are more susceptible to PAH exposure.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2022)
Article
Chemistry, Analytical
Mir Mahdi Abolghasemi, Marzieh Piryaei
Summary: The study developed a coordination replication approach using Cu(OH)2 nano-rod arrays as sacrificial template to create Cu-based metal-organic frameworks. The technique showed good sensitivity and linear range under optimal conditions, along with quick thermal stability and high relative recovery rate.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Qiong Jiang, Shuwu Zhang, Juanjuan Feng, Min Sun
Summary: In this study, a hybrid material was used to improve the extraction performance of silica aerogel, and a fiber-filled extraction tube was successfully prepared. The developed online extraction and detection method showed excellent sensitivity and accuracy in the analysis of polycyclic aromatic hydrocarbons.
Article
Environmental Sciences
Jijie Kong, Xiaoyu Cao, Wen Huang, Chao Li, Qiming Xian, Shaogui Yang, Shiyin Li, Cheng Sun, Huan He
Summary: This study compared the efficiency of a self-made ZIF-8/h-BN solid-phase microextraction (SPME) fiber and commercial Tenax in predicting the bioavailability of nitrated polycyclic aromatic hydrocarbons (NPAHs) in sediments. The results showed that the NPAH concentrations reached extraction equilibrium after 72 h for the ZIF-8/h-BN fibers and after 168 h for the Tenax extraction. The SPME fiber extraction of NPAHs in sediments fitted well with the pseudo first-order kinetic model.
ENVIRONMENTAL POLLUTION
(2023)
Article
Chemistry, Analytical
Min Sun, Xiangping Ji, Mingxia Sun, Wenjuan Guo, Juanjuan Feng
Summary: In order to improve the extraction ability of carbon fibers for microextraction of polycyclic aromatic hydrocarbons, biochar nanospheres derived from glucose were grown onto the surface of carbon fibers via hydrothermal synthesis. The biochar nanospheres greatly enhanced the extraction efficiency of carbon fibers, resulting in the development of an online analytical method for microextraction and determination of several PAHs with satisfactory results.
Article
Chemistry, Analytical
Min Sun, Juanjuan Feng, Sen Han, Xiangping Ji, Chunying Li, Jiaqing Feng, Haili Sun, Jing Fan
Summary: The PIL-hybridized silica aerogel prepared by sol-gel method was used for SPME, providing good extraction performance for PAHs. The method established low detection limits and wide linear ranges with good linear coefficients for PAHs, and showed higher sensitivity, shorter extraction time, and better repeatability compared to other extraction coatings.
Article
Chemistry, Analytical
Chaoqun Lian, Xilan Feng, Mengkui Tian, Yuan Tian, Yuping Zhang
Summary: Electrochemical deposition has been widely used to manufacture metal-organic framework (MOF) coatings. In this study, a zeolitic imidazolate framework (ZIF) coating solid-phase microextraction fiber was successfully prepared using stainless steel wire as the support material. The fabrication process, which did not require the addition of any supporting electrolyte or regulator, resulted in the formation of ZIF-8 coating fiber within 20 minutes at room temperature. The key factors affecting the preparation of the ZIF-8 coated fiber were optimized. The performance of the fiber was evaluated using simulated pollutants, and the results demonstrated its suitability for HS-SPME-FID analysis.
MICROCHEMICAL JOURNAL
(2022)
Article
Environmental Sciences
Leticia Aguilar, Maurilio Lara-Flores, Jaime Rendon-von Osten, Jorge A. Kurczyn, Bruno Vilela, Andre Luis da Cruz
Summary: The study found that polycyclic aromatic hydrocarbons have an impact on gene expression in Gambusia yucatana, particularly affecting reproductive genes. Benzo[a]pyrene is likely the main PAH responsible for these effects. These genes can serve as molecular markers for endocrine-disrupting compounds, allowing for early identification of the impacts of oil pollution.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Chemistry, Analytical
Yijun Zhang, Yingying Wang, Chun-Xiang Li, Xiaowen Chen, Zhenyu Lu, Mingxia Zhang, Xiaohui Zhu, Yunjiang Yu
Summary: In this study, a beta-cyclodextrin-based hyper-crosslinked polymer was prepared and used as a coating for the analysis of PAHs in water samples. The coating showed excellent adsorption performance and has potential applications for the pretreatment of PAHs in various aqueous environmental samples.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Min Sun, Xiuqin Wang, Yali Ding, Juanjuan Feng
Summary: To improve the selectivity and stability of melamine-formaldehyde aerogel, researchers composites it with TiO2 aerogel. The TiO2-MF hybrid aerogel was prepared on carbon fibers for in-tube solid-phase microextraction. The method showed favorable extraction performance for various environmental pollutants and achieved high sensitivity with low detection limits.
Article
Chemistry, Analytical
Akang Dan, Shasha Zhang, Zhongliang Chen, Jinghan Dong, Wenjun Zheng, Yuxin Tu, Zian Lin, Zongwei Cai
Summary: A simple and highly selective analytical method for phthalate monoesters (mPAEs) was developed using Cu2+-immobilized magnetic covalent organic frameworks. The method showed wide linear ranges, low limits of detection, and good correlation coefficients for the detection of mPAEs. The method was successfully applied to the sensitive detection of mPAEs in mouse plasma samples.
Review
Chemistry, Analytical
Jun Ding, Yu-Qi Feng
Summary: In clinical metabolomics, the use of mass spectrometry (MS) as an analytical platform is essential for characterizing metabolic disturbances, providing diagnostic evidence, and delivering qualitative and quantitative information of the broad metabolome in clinical samples. This review summarizes recent progress in sample collection, preparation, data acquisition, and normalization, and discusses the applications of metabolomics in biomarker screening, disease phenotyping, and clinical outcome prediction. The future directions of clinical metabolomics are also addressed.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Review
Cell Biology
Xiaolei Qiu, Zhuoyue Deng, Meijing Wang, Yuqi Feng, Lintao Bi, Lisha Li
Summary: Piezo ion channel, including Piezo1 and Piezo2, is a mechanosensitive protein on the cell membrane that responds to mechanical forces such as stretch, matrix stiffness, static pressure, and shear stress. These Piezo channels transmit mechanical signals and activate downstream pathways involved in stem cell differentiation, including integrin signaling, ERK1/2 MAPK signaling, Notch signaling, and WNT signaling. Differences in Piezo channel expression have been found in the fate of stem cell differentiation and are associated with developmental diseases. This review provides a comprehensive overview of the structure and function of Piezo channels, their relationship with mechanical signals, and their role in stem cell fate and developmental diseases.
Article
Chemistry, Applied
Yinchun Fang, Jianguo Wu, Guojie Ma, Qufu Wei
Summary: Polylactic acid (PLA) fibre is a renewable and biodegradable synthetic polymer that has gained attention in textiles. However, its dyeing process faces challenges, and a waterless dyeing method using disperse dyes is being explored as an alternative. This study investigated the waterless dyeing of PLA fibre using different disperse dyes and decamethylcyclopentasiloxane (D5) as the medium. Optimal dyeing process conditions were determined, and it was found that disperse dyes with a monoazo structure were most suitable for PLA waterless dyeing. The research provides a basis for developing suitable dyes for waterless dyeing of PLA using D5.
COLORATION TECHNOLOGY
(2023)
Article
Engineering, Biomedical
Yuanrong Li, Jianguo Wu, Chuanjiang He, Honghui He, Mingjun Xie, Ke Yao, Jing He, Yan Duan, Liujing Zhaung, Ping Wang, Yong He
Summary: Many mammalian tissues have specific cellular arrangements under stress stimulus, but conventional 3D encapsulation fails to replicate these arrangements accurately, so advanced cellular arrangement approaches are needed. In this study, a novel 3D prestress bioprinting approach is developed, using static sustained tensile stress, molecular chain orientation, and slow crosslinking in bioink to guide tissue construction. The semi-crosslinking state of the bioink provides excellent elasticity for applying stress on cells during the printing process. After printing, the bioink gradually crosslinks and maintains the applied stress force to induce cell-orientated growth. This approach allows for directional arrangement of multiple cell types, with adjustable internal stress in the hydrogel filament, and has potential applications in engineering skeletal muscles, tendons, ligaments, vascular networks, or combinations thereof.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Engineering, Industrial
Ruiyu Xu, Song Huang, Zheren Song, Yuanyuan Gao, Jianguo Wu
Summary: This article proposes a deep mixed-effects modeling approach for anomaly detection in additive manufacturing. It captures the relationship between the melt pool temperature and other sensing data using a deep neural network, and incorporates random-effect and residual terms to account for variations and autocorrelations. Control charts based on T2 and generalized likelihood ratio statistics are developed for online monitoring.
Article
Environmental Sciences
Guanghui Zhao, Taihu Sun, Dongqi Wang, Shu Chen, Yan Ding, Yilan Li, Guitao Shi, Hechen Sun, Shengnan Wu, Yizhe Li, Chenyang Wu, Yufang Li, Zhongjie Yu, Zhenlou Chen
Summary: This study used stable isotopes to investigate the sources and transformation processes of nitrate in Suzhou Creek. The results showed that treated wastewater, soil nitrogen, and nitrogen fertilizer were the main sources of nitrate in the river. Reducing nitrate concentrations in treated wastewater is crucial for addressing nitrogen pollution in urban rivers.
ENVIRONMENTAL RESEARCH
(2023)
Article
Engineering, Environmental
Guodong Cao, Wei Wang, Jing Zhang, Pengfei Wu, Han Qiao, Huankai Li, Gefei Huang, Zhu Yang, Zongwei Cai
Summary: para-Phenylenediamine quinones (PPD-Qs) are newly discovered transformation products derived from para-phenylenediamine (PPD) antioxidants. Their occurrence and fate in wastewater treatment plants (WWTPs) need further investigation to improve pollutant removal efficiency.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Geochemistry & Geophysics
Imali Kaushalya Herath, Guitao Shi, Qian Zhao, Yilan Li, Danhe Wang, Su Jiang, Yangjie Li, Zhenlou Chen, Roberto Bargagli
Summary: This study analyzed the sources and cycling of nitrate (NO3-) in Antarctic soils. The research found that NO3- concentrations and isotopic values were consistent across the latitudinal gradient, with the majority of NO3- derived from nitrification process. Atmospheric deposition contributed minimally to the NO3- budget, and there was evidence of denitrification and cycling between NO3- and nitrite (NO2-). These findings provide new insights into the nitrogen cycle in Antarctic terrestrial ecosystems.
GEOCHIMICA ET COSMOCHIMICA ACTA
(2023)
Review
Engineering, Biomedical
Haiyan Li, Keerthi Subramanian Iyer, Lei Bao, Jiali Zhai, Jiao Jiao Li
Summary: Granular microporous hydrogels made of non-spherical microgels show enhanced characteristics compared to traditional nanoporous hydrogels, promoting cell viability, migration, and tissue regeneration. These hydrogels have higher macroporosity and improved mechanical properties, allowing for better alignment and differentiation of cells in anisotropic tissue. The development of these hydrogels is gaining increasing interest in regenerative medicine.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Cheng-Jie Ma, Gaojie Li, Wen-Xuan Shao, Yi-Hao Min, Ping Wang, Jiang-Hui Ding, Neng-Bin Xie, Min Wang, Feng Tang, Yu-Qi Feng, Weimin Ci, Yinsheng Wang, Bi-Feng Yuan
Summary: Researchers developed a method called deaminase-mediated sequencing (DM-seq) to map the presence of 6mA in DNA at single-nucleotide resolution. They found that 6mA is mainly located in the GATC motif in E. coli genome and identified 17 6mA sites in mtDNA of HepG2 cells, all of which are in the heavy strand. DM-seq is expected to be a valuable tool for studying the functions of 6mA in DNA and its potential roles in mitochondria-related human diseases.
ACS CENTRAL SCIENCE
(2023)
Article
Chemistry, Analytical
Yaqi Zhu, Saiyi Zhong, Xitian Peng, Qiongwei Yu, Yuqi Feng
Summary: A simple and sensitive method combining solid-phase extraction (SPE) and high-performance liquid chromatography-ultraviolet detection (HPLC-UV) was developed for the determination of benzo[a]pyrene (BaP) in fish. Loofah sponge (LS) was carbonized and used as an SPE adsorbent. The optimized method showed good accuracy and precision with a wide linear range and low detection limit, making it a low-cost and environmentally friendly alternative for the determination of BaP in aquatic products.
ANALYTICAL METHODS
(2023)
Article
Chemistry, Analytical
Min Wang, Neng-Bin Xie, Ke-Ke Chen, Tong-Tong Ji, Jun Xiong, Xia Guo, Si-Yu Yu, Feng Tang, Conghua Xie, Yu-Qi Feng, Bi-Feng Yuan
Summary: DNA methylation (5mC) is an important epigenetic modification in mammals and its roles are deciphered by detecting 5mC at single-base resolution. Bisulfite sequencing (BS-seq) is commonly used for mapping 5mC but causes DNA damage. Here, we engineered the A3C protein to develop an engineered A3C sequencing (EAC-seq) method, which can quantitatively map 5mC without bisulfite treatment. The EAC-seq approach, employing mild reaction conditions, is a valuable tool for the quantitative detection of 5mC at single-base resolution.
ANALYTICAL CHEMISTRY
(2023)
Article
Biochemical Research Methods
Sha Li, Zheng Zhang, Fei-Long Liu, Bi-Feng Yuan, Tian-Gang Liu, Yu-Qi Feng
Summary: We developed an LC-MS method using isotope reagents for the comprehensive analysis of phosphomonoester metabolites. This method allowed for rapid screening, identification, and relative quantification of the metabolites in Saccharomyces cerevisiae. We identified 42 phosphomonoester metabolites, including two that were detected for the first time in S. cerevisiae. The relative quantification results revealed significant differences in certain metabolites between lycopene-producible and wild-type S. cerevisiae, indicating a close relationship between phosphomonoesters and lycopene production.
JOURNAL OF PROTEOME RESEARCH
(2023)
Review
Biochemistry & Molecular Biology
Hui Chen, Cheng Jin, Li Xie, Jian Wu
Summary: Succinate, an intermediate of the TCA cycle, is crucial in mitochondrial metabolism, energy production, and is also considered a signaling molecule in metabolism and hepatic diseases. Its downstream signaling pathway through GPR91 leads to various intracellular responses, including succinylation, ROS production, HIF-1 alpha stabilization, and significant impact in cellular metabolism due to its role in the TCA cycle. Understanding the signaling mechanisms of succinate in hepatic fibrosis, metabolic reprogramming, inflammatory or immune responses, and carcinogenesis is of great interest. This review aims to provide the current understanding of succinate in mediating metabolism, inflammatory and immune responses in liver diseases, with the aim of establishing a molecular basis for therapeutic strategies.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
(2024)
Correction
Biochemical Research Methods
Yong Wang, Suhua Yu, Rui Li, Jing Wan, Yuheng Wang, Zongli Huo, Chunyong Wu, Li Mi, Songqin Liu
JOURNAL OF CHROMATOGRAPHY A
(2024)
Review
Biochemical Research Methods
Israel D. Souza, Maria Eugenia C. Queiroz
Summary: Organic-silica hybrid monolithic materials have gained significant attention in separation science and sample preparation due to their unique properties. This review summarizes the characteristics, current status, and recent developments of these materials, as well as discusses synthesis methods, characterization techniques, and strategies for improving extraction efficiency in various applications.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Bhagwat Upreti, Bhanu Prasad Vempatapu, Jagdish Kumar, Pankaj K. Kanaujia
Summary: Lubricating oils are essential for the effective performance of internal combustion engines. This study presents a new HPLC method for determining additives in finished lubricating oils and polar substances in used engine oils.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zongqing Huang, Haoju Hua, Xiuzhen Du, Zipeng Zhen, Wei Zhao, Jun Feng, Ji-an Li
Summary: This study successfully isolated VHHs against the SUMO protein for the first time using biopanning of an immune camelid nanobody library. The VHHs were coupled to agarose resins to form affinity chromatography resins, allowing for one-step purification of various SUMO fusions.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Xueting Qiu, Xuben Hou, Yue Yang, Hao Fang, Fei Cui, Xinying Yang
Summary: In this study, a new method based on electrophoretically mediated microanalysis was developed for the investigation of PTPRO enzymatic activity. The method was successfully used to determine the kinetics of PTPRO and the inhibitory concentration of PTPRO inhibitors. The method exhibited improved accuracy and reduced consumption compared to traditional methods.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Feifei Luo, Mengmeng Hao, Lei Zhang, Yangguo Xie, Wei Hou, Hongya Wang, Zhongli Zhang
Summary: In this study, a comprehensive screening and structure elucidation of 23 nonvolatile organic compounds (NVOCs) in two antibody drugs was conducted. Seven previously unreported compounds were identified. A quantitative method with high sensitivity, accuracy, and precision was developed for evaluating the safety of NVOCs in drug products.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zuzana Vosahlova, Kveta Kalfkova, Martin Gilar, Jakub Szymarek, Maria Mazurkiewicz-Beldzinska, Sylwia Studzi
Summary: A hydrophilic interaction liquid chromatography method was developed for the separation and identification of oligonucleotide impurities and metabolites, and successfully applied to the analysis of serum samples from Spinraza-treated patients.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Aswanidevi Kongasseri, Thirumalai Madhesan, Sangeetha Krishna Kumar, Sushmitha Pedugu Sivaraman, Suchashrita Mitra, Pitchaiah Kancharlapalli Chinaraga, C. V. S. Brahmmananda Rao, Sivaraman Nagarajan, Prabhakaran Deivasigamani, Akhila Maheswari Mohan
Summary: This study focuses on the sequential separation of trivalent lanthanides using modified C-18 silica-packed supports and reversed-phase HPLC technique. By tuning the column modifiers and separation parameters, the researchers achieved systematic separation of Ln(3+). The results showed that the choice of column modifiers and fine-tuning of the modification procedure were crucial for achieving excellent separation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Raquel Perez-Robles, Szabolcs Fekete, Robert Kormany, Natalia Navas, Davy Guillarme
Summary: There is a mismatch between the sample diluent and the mobile phase in HILIC analysis, leading to analyte breakthrough and peak distortion. Adding a weak solvent for pre-injection can effectively prevent these issues and improve sensitivity.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oleg Pokrovskiy, Irina Rostovschikova, Konstantin Ustinovich, Ilya Voronov, Dmitry Kosyakov
Summary: A chromatography-like propagation of water through the material bed was observed during supercritical fluid extraction of aroma plants with high moisture content, which could be significant for modeling the kinetics of supercritical fluid extraction of non-volatile compounds.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Yasar Kemal Recepoglu, Ozguer Arar, Asli Yuksel
Summary: Biosorption using phosphorylated hazelnut shell waste (FHS) is a promising method for lithium removal and recovery. This study investigated the performance of a continuous-flow packed-bed column system using FHS for ultra-low level lithium removal. The results showed that the lihium biosorption capacity of the FHS column was unaffected by the bed height, but decreased with increasing flow rate.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Jian Sun, Zheheng Zheng, Zixiao Jia, Jiabin Wang, Xucong Lin
Summary: In this study, an ionic covalent organic framework (iCOF) surface grafting monolithic sorbent was prepared for in-tube solid-phase microextraction (SPME) of aristolochic acids (AAs) in various samples. The density of quaternary ammonium ions in the iCOF was modulated for enhanced adsorption of AAs. The iCOF surface grafting monolithic sorbent was confirmed by different means. Several operating conditions were optimized to develop the online in-tube SPME-HPLC method, which showed good linearity, low limits of detection, and high recoveries for AAs in serum samples. This study presents a feasible approach for the application of COF-based monolithic sorbents in sample preparation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zeng Wen, Ruihan Peng, Die Gao, Jing Lin, Jia Zeng, Zhou Li, Famin Ke, Zhining Xia, Dandan Wang
Summary: A chitosan-alginate sponge with multiple cross-linking networks was developed for adsorption and enrichment of anionic dyes from food samples. The sponge showed better three-dimensional network structure, mechanical behavior, and stability compared to pure chitosan and alginate sponges. The adsorption performance and selectivity of the sponge were systematically studied, and it maintained high adsorption capacity and selectivity for anionic dyes. The sponge also showed satisfactory reusability and was successfully combined with high-performance liquid chromatography for the enrichment and detection of anionic dyes in candy and cocktail samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Hairong Zhang, Xiaojuan Jiang, Dandan Zhang, Yuexin Yang, Qiang Xie, Caisheng Wu
Summary: Analysis of in vivo exposure to traditional Chinese medicine using mass spectrometry is helpful for identifying effective ingredients and developing new drugs. This study focused on Forsythia suspensa (Lian Qiao) and used metabolomics technology to explore its in vivo exposure. By comparing the differences before and after administration, a complete set of nontargeted analysis strategies for TCM exposure was established. The study identified 393 Lian Qiao-related chemical components in mice after administration, including prototypes and metabolites. This study provides a reference for research on the active ingredients of Lian Qiao in vivo.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oscar Castejon-Musulen, Ricardo Lopez, Ignacio Ontan, Vicente Ferreira
Summary: A quantitative analytical method was developed and validated in this study to determine the concentrations of 81 aroma-relevant wine volatiles. The method utilizes stir bar sorptive extraction and multidimensional gas chromatography with flame ionization detector or mass spectrometer. The method demonstrated good linearity, reproducibility, and recovery, and was successfully applied to analyze 20 wine samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)
