Article
Chemistry, Analytical
Mengshu Han, Jijie Kong, Yuting Wang, Wen Huang, Gancheng Zuo, Fengxiao Zhu, Huan He, Cheng Sun, Qiming Xian
Summary: NPAHs are emerging pollutants that are widely present in the environment. SPME is a valuable technique for detecting trace pollutants, and advancements in fiber preparation have improved its performance. In this study, ZIF-8/h-BN coating material was successfully synthesized and used to prepare SPME fibers for analyzing NPAHs in environmental water samples.
MICROCHEMICAL JOURNAL
(2022)
Article
Biochemical Research Methods
Yanyan Wang, Lili Lian, Xiyue Wang, Boying Yue, Lan Ding, Dawei Lou
Summary: In this study, velvet-like carbon nitride (V-g-C3N4) was prepared and modified on the surface of stainless-steel wire to obtain a solid-phase microextraction (SPME) coating for the extraction of polycyclic aromatic hydrocarbons (PAHs) from water samples. The method showed excellent performance in extraction efficiency and durability.
JOURNAL OF CHROMATOGRAPHY A
(2022)
Article
Chemistry, Analytical
Mir Mahdi Abolghasemi, Marzieh Piryaei
Summary: The study developed a coordination replication approach using Cu(OH)2 nano-rod arrays as sacrificial template to create Cu-based metal-organic frameworks. The technique showed good sensitivity and linear range under optimal conditions, along with quick thermal stability and high relative recovery rate.
MICROCHEMICAL JOURNAL
(2021)
Article
Environmental Sciences
Jijie Kong, Xiaoyu Cao, Wen Huang, Chao Li, Qiming Xian, Shaogui Yang, Shiyin Li, Cheng Sun, Huan He
Summary: This study compared the efficiency of a self-made ZIF-8/h-BN solid-phase microextraction (SPME) fiber and commercial Tenax in predicting the bioavailability of nitrated polycyclic aromatic hydrocarbons (NPAHs) in sediments. The results showed that the NPAH concentrations reached extraction equilibrium after 72 h for the ZIF-8/h-BN fibers and after 168 h for the Tenax extraction. The SPME fiber extraction of NPAHs in sediments fitted well with the pseudo first-order kinetic model.
ENVIRONMENTAL POLLUTION
(2023)
Article
Chemistry, Analytical
Min Sun, Juanjuan Feng, Sen Han, Xiangping Ji, Chunying Li, Jiaqing Feng, Haili Sun, Jing Fan
Summary: The PIL-hybridized silica aerogel prepared by sol-gel method was used for SPME, providing good extraction performance for PAHs. The method established low detection limits and wide linear ranges with good linear coefficients for PAHs, and showed higher sensitivity, shorter extraction time, and better repeatability compared to other extraction coatings.
Article
Biochemical Research Methods
Xingru Hu, Long Pang, Mingkai Wu, Chaohai Wang, Jiansheng Li
Summary: In this study, a newly synthesized solid-phase microextraction fiber material named NLCs-F showed excellent performance in the sensitive extraction of polycyclic aromatic hydrocarbons. The material exhibited abundant adsorption active sites and selective extraction capability, making it suitable for the enrichment of PAHs in actual samples.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Environmental Sciences
N. Riboni, M. Amorini, F. Bianchi, A. Pedrini, R. Pinalli, E. Dalcanale, M. Careri
Summary: A sensitive and selective method based on solid-phase microextraction-gas chromatography-mass spectrometry was developed for the simultaneous determination of 16 PAHs in snow samples. The method achieved low detection limits and demonstrated reliability in the analysis of these compounds at ultra-trace levels.
Article
Chemistry, Analytical
Yahuan Li, Yang Li, Qingyun Chang, Xiaohuan Zang, Shuaihua Zhang, Chun Wang, Zhi Wang
Summary: MXene-polyvinylpyrrolidone (MXene-PVP) was prepared by physically doping and spray drying to overcome the aggregation issue of MXene. The resulting MXene-PVP was carbonized to create a carbonized MXene-PVP (MXene-PVP-C), which was then immobilized on a stainless steel wire using the sol-gel approach to produce a solid-phase microextraction (SPME) fiber. This fiber was used to extract polycyclic aromatic hydrocarbons (PAHs) from tea beverages, and the extracted PAHs were detected using gas chromatography. Central composite design methodology was employed to investigate the main SPME parameters. Under optimized conditions, the method achieved low detection limits (0.03-0.15 μg/L) and quantification limits (0.10-0.50 μg/L) for the PAHs. The method exhibited good recoveries (78.6% to 122%) for the spiked PAHs in tea beverages, with low relative standard deviations (less than 8.2% for single-fiber and 9.6% for fiber-to-fiber).
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Zhuo Wang, Ying Zhang, Guifen Chang, Jinqiu Li, Xiumin Yang, Shuaihua Zhang, Xiaohuan Zang, Chun Wang, Zhi Wang
Summary: The study presents a novel coating material for solid-phase microextraction based on a triazine-based covalent organic polymer, which shows enhanced extraction efficiency for polycyclic aromatic hydrocarbons and their derivatives. The newly-developed method coupled with gas chromatography/flame ionization detection demonstrates high sensitivity and accuracy in the determination of these compounds.
JOURNAL OF SEPARATION SCIENCE
(2021)
Article
Chemistry, Analytical
Yueru Shi, Shuyao Huang, Yixin Kuang, Zexun Chen, Jing Guo, Shufen Cui, Juan Zheng, Gangfeng Ouyang
Summary: The study introduces a novel method to fabricate SPME thin membrane for efficient enrichments of OH-PAHs. The OMC-PDMS membrane shows the best extraction efficiencies and can be used for trace OH-PAHs enrichment in human urine, with detection limits ranging from 0.15-0.39 ng L-1 and satisfactory recoveries of 82.1%-115%.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Analytical
Chen Yu, Fengshou Wu, Xiaogang Luo, Juan Zhang
Summary: A porphyrin-based COF was synthesized and applied for the headspace solid-phase microextraction of PAHs, with optimized parameters leading to a wide linear range, low detection limits, and excellent repeatability. The method showed satisfactory recoveries of PAHs in water and soil samples, indicating its potential for environmental analysis.
MICROCHEMICAL JOURNAL
(2021)
Article
Engineering, Chemical
Xuemei Wang, Zhen Zhang, Jing Ru, Pengfei Huang, Yuan Ma, Jie Zhang, Xinzhen Du, Xiaoquan Lu
Summary: In this study, an innovative MOFs@COFs-based molecular trap material was developed and used as a solid-phase microextraction (SPME) fiber coating, combined with high performance liquid chromatography (HPLC), to achieve efficient separation, capture, and detection of polycyclic aromatic hydrocarbons (PAHs). The method showed a wide linear range, low detection limits, and excellent stability and reproducibility.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)
Article
Chemistry, Analytical
Yuanqing Zhao, Kai Hu, Xiaobing Liu, Lixin Li, Zhonghua Li, Pan Wang, Zhenqiang Zhang, Shusheng Zhang
Summary: In this study, covalent organic framework@MXene composites were synthesized and used as solid phase microextraction coatings for the isolation of PAHs from honey samples. The developed composites exhibited excellent extraction capacity and analytical performance, as well as long lifetime and good reproducibility. This study provides an effective method for the analysis of trace PAHs in complex food samples.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
N. Riboni, F. Bianchi, M. Scaccaglia, F. Bisceglie, A. Secchi, C. Massera, P. Luches, M. Careri
Summary: Novel solid-phase microextraction coatings based on MWCNT-CD nanocomposites were developed for ultratrace determination of 16-priority PAHs in snow samples. The use of MWCNTs-H2O2-γ-CD fiber showed superior results in facilitating the interactions between MWCNTs and CDs. The method proved to be reliable with detection and quantitation limits below 0.7 and 2.3 ng/L, RSD lower than 21%, and recoveries of 88(+/- 2)-119.8(+/- 0.4)%.
Article
Chemistry, Analytical
Pelin Erdem, Aylin Altinisik Tagac, Serap Seyhan Bozkurt, Melek Merdivan
Summary: In this study, a novel SPME fiber was prepared for the extraction and analysis of polycyclic aromatic hydrocarbons. The MMT/CH/O-DIL fiber showed wider linear ranges, lower limits of detection, high extraction recoveries, and good reproducibility compared to traditional fibers.
Article
Chemistry, Multidisciplinary
Mattia Amorini, Nicolo Riboni, Lucia Pesenti, Valentina Antonia Dini, Alessandro Pedrini, Chiara Massera, Chiara Gualandi, Federica Bianchi, Roberta Pinalli, Enrico Dalcanale
Summary: This study introduces a regenerable membrane for the efficient removal of toxic and carcinogenic PAHs from water, utilizing a cavitand receptor in electrospun PAN fibers. The effective uptake/release of PAHs is demonstrated through the design and synthesis of the cavitand receptor BenzoQxCav, with a removal efficiency ranging from 32% to 99%. The membrane's regeneration is achieved by exploiting the pH-driven conformational switching of the cavitand between vase and kite forms.
Article
Chemistry, Analytical
Simone Fortunati, Marco Giannetto, Chiara Giliberti, Angelo Bolchi, Davide Ferrari, Massimo Locatelli, Valentina Bianchi, Andrea Boni, Ilaria De Munari, Maria Careri
Summary: Innovative and highly performing smart voltammetric immunosensors for rapid and effective serological tests aimed at the determination of SARS-CoV-2 antibodies were developed and validated. The sensors achieved fast quantitative detection using modified disposable screen-printed electrodes and a smart potentiostat. The sensors demonstrated outstanding sensitivity, specificity, and accuracy, making them suitable for high-throughput diagnostics when combined with the portability of an IoT-based device.
Review
Biochemical Research Methods
Monica Mattarozzi, Eleni Laski, Alessandro Bertucci, Marco Giannetto, Federica Bianchi, Claudia Zoani, Maria Careri
Summary: Traditional techniques for food analysis are not suitable for real-time monitoring and decision-making. The future of food testing requires rapid, portable and simple methods, as well as process analytical technologies for improved product quality and safety.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Construction & Building Technology
Roberto Valentino, Franco Bisceglie, Elena Romeo
Summary: Polyurethane resins are commonly used in geotechnical applications to improve soil properties and stabilize structures. This study investigated the effects of long-term aging on the mechanical, physical, and chemical behavior of polyurethane resin specimens. Artificial aging experiments were conducted using various methods to simulate underground conditions. The results showed that accelerated aging had no significant impact on the volume change or mechanical properties of the polyurethane resins. The tested resins exhibited high durability, stability, and maintained their deformability and strength under conditions similar to those in the ground. Infrared spectroscopy analysis also indicated no chemical degradation in the resins.
JOURNAL OF MATERIALS IN CIVIL ENGINEERING
(2023)
Article
Chemistry, Analytical
N. Riboni, F. Bianchi, M. Scaccaglia, F. Bisceglie, A. Secchi, C. Massera, P. Luches, M. Careri
Summary: Novel solid-phase microextraction coatings based on MWCNT-CD nanocomposites were developed for ultratrace determination of 16-priority PAHs in snow samples. The use of MWCNTs-H2O2-γ-CD fiber showed superior results in facilitating the interactions between MWCNTs and CDs. The method proved to be reliable with detection and quantitation limits below 0.7 and 2.3 ng/L, RSD lower than 21%, and recoveries of 88(+/- 2)-119.8(+/- 0.4)%.
Article
Multidisciplinary Sciences
Nicolo' Riboni, Federica Bianchi, Monica Mattarozzi, Marianna Peracchia, Marco Meleti, Maria Careri
Summary: Dental calculus serves as a valuable resource for reconstructing the dietary habits and oral microbiome of ancient populations. This study aimed to investigate the dental calculus metabolome of a noble couple using untargeted metabolomics. The findings identified over 200 metabolites, with fatty acids, alcohols, aldehydes, phosphatidylcholines, phosphatidylglycerols, ceramides, and phosphatidylserines being the most abundant classes.
SCIENTIFIC REPORTS
(2023)
Article
Green & Sustainable Science & Technology
Pietro Rizzo, Antonio Bucci, Pamela Monaco, Anna Maria Sanangelantoni, Gino Naclerio, Mattia Rossi, Paola Iacumin, Federica Bianchi, Claudio Mucchino, Nicolo Riboni, Dario Avagliano, Francesco Coraggio, Antonella Caputi, Fulvio Celico
Summary: The increase in oil production has led to studies on the effects of oil activities on groundwater quality. Oily wastewater from oil production is often reinjected into unproductive areas of the reservoir to avoid surface discharge. Evaluating the compatibility between this process and environmental protection is crucial in sensitive and protected areas.
Article
Pharmacology & Pharmacy
Serena Montalbano, Franco Bisceglie, Giorgio Pelosi, Mirca Lazzaretti, Annamaria Buschini
Summary: Since the discovery of cisplatin, the search for metal-based compounds with therapeutic potential has been a challenge for the scientific community. Thiosemicarbazones and their metal derivatives, such as the three metal thiosemicarbazones [Ni(tcitr)(2)], [Pt(tcitr)(2)], and [Cu(tcitr)(2)] investigated in this study, show promise as anticancer agents with high selectivity and low toxicity. The study deepened the understanding of the molecular action mechanism of these compounds and demonstrated their potential as candidate antiproliferative thiosemicarbazones, although the overall molecular mechanism is still to be understood.
Review
Chemistry, Analytical
Nicolo Riboni, Federica Bianchi, Antonella Cavazza, Maurizio Piergiovanni, Monica Mattarozzi, Maria Careri
Summary: The safety of food contact materials is a major concern due to potential chemical migration into food and its impact on health and organoleptic properties. Mass spectrometry is the preferred analytical technique for detecting and quantifying intentionally and non-intentionally added substances in packaging materials. Hyphenated mass spectrometry-based techniques, particularly high-resolution methods, are effective in identifying migrating compounds without extensive sample preparation, reducing analysis costs and time. This article discusses examples of migration of contaminants from bioplastic materials and presents the state-of-the-art mass spectrometry approaches used from 2012 to 2022.
Article
Agriculture, Multidisciplinary
Nicolo Riboni, Federica Bianchi, Monica Mattarozzi, Marina Caldara, Mariolina Gulli, Sara Graziano, Elena Maestri, Nelson Marmiroli, Maria Careri
Summary: This study investigated the effects of sustainable treatments on durum wheat using metabolomics. The addition of biochar-biostimulants was found to effectively up-regulate lipids and flavonoids, while down-regulating carbohydrates in wheat.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Engineering, Electrical & Electronic
Andrea Boni, Valentina Bianchi, Simone Fortunati, Marco Giannetto, Maria Careri, Ilaria De Munari
Summary: In recent years, portable potentiostats have become popular for electrochemical analyses outside the labs, moving them to home or point of care (PoC) environments. Performing multiple acquisitions simultaneously is attractive for replicates or simultaneous quantitative assessments, saving time and increasing data reliability. This article describes a multichannel Wi-Fi-based portable potentiostat with four independent channels, low power consumption, excellent linearity, and negligible crosstalk. It was successfully tested in a real case scenario, reducing acquisition time by 76% compared to a single channel solution.
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
(2023)
Correction
Biochemical Research Methods
Yong Wang, Suhua Yu, Rui Li, Jing Wan, Yuheng Wang, Zongli Huo, Chunyong Wu, Li Mi, Songqin Liu
JOURNAL OF CHROMATOGRAPHY A
(2024)
Review
Biochemical Research Methods
Israel D. Souza, Maria Eugenia C. Queiroz
Summary: Organic-silica hybrid monolithic materials have gained significant attention in separation science and sample preparation due to their unique properties. This review summarizes the characteristics, current status, and recent developments of these materials, as well as discusses synthesis methods, characterization techniques, and strategies for improving extraction efficiency in various applications.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Bhagwat Upreti, Bhanu Prasad Vempatapu, Jagdish Kumar, Pankaj K. Kanaujia
Summary: Lubricating oils are essential for the effective performance of internal combustion engines. This study presents a new HPLC method for determining additives in finished lubricating oils and polar substances in used engine oils.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zongqing Huang, Haoju Hua, Xiuzhen Du, Zipeng Zhen, Wei Zhao, Jun Feng, Ji-an Li
Summary: This study successfully isolated VHHs against the SUMO protein for the first time using biopanning of an immune camelid nanobody library. The VHHs were coupled to agarose resins to form affinity chromatography resins, allowing for one-step purification of various SUMO fusions.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Xueting Qiu, Xuben Hou, Yue Yang, Hao Fang, Fei Cui, Xinying Yang
Summary: In this study, a new method based on electrophoretically mediated microanalysis was developed for the investigation of PTPRO enzymatic activity. The method was successfully used to determine the kinetics of PTPRO and the inhibitory concentration of PTPRO inhibitors. The method exhibited improved accuracy and reduced consumption compared to traditional methods.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Feifei Luo, Mengmeng Hao, Lei Zhang, Yangguo Xie, Wei Hou, Hongya Wang, Zhongli Zhang
Summary: In this study, a comprehensive screening and structure elucidation of 23 nonvolatile organic compounds (NVOCs) in two antibody drugs was conducted. Seven previously unreported compounds were identified. A quantitative method with high sensitivity, accuracy, and precision was developed for evaluating the safety of NVOCs in drug products.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zuzana Vosahlova, Kveta Kalfkova, Martin Gilar, Jakub Szymarek, Maria Mazurkiewicz-Beldzinska, Sylwia Studzi
Summary: A hydrophilic interaction liquid chromatography method was developed for the separation and identification of oligonucleotide impurities and metabolites, and successfully applied to the analysis of serum samples from Spinraza-treated patients.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Aswanidevi Kongasseri, Thirumalai Madhesan, Sangeetha Krishna Kumar, Sushmitha Pedugu Sivaraman, Suchashrita Mitra, Pitchaiah Kancharlapalli Chinaraga, C. V. S. Brahmmananda Rao, Sivaraman Nagarajan, Prabhakaran Deivasigamani, Akhila Maheswari Mohan
Summary: This study focuses on the sequential separation of trivalent lanthanides using modified C-18 silica-packed supports and reversed-phase HPLC technique. By tuning the column modifiers and separation parameters, the researchers achieved systematic separation of Ln(3+). The results showed that the choice of column modifiers and fine-tuning of the modification procedure were crucial for achieving excellent separation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Raquel Perez-Robles, Szabolcs Fekete, Robert Kormany, Natalia Navas, Davy Guillarme
Summary: There is a mismatch between the sample diluent and the mobile phase in HILIC analysis, leading to analyte breakthrough and peak distortion. Adding a weak solvent for pre-injection can effectively prevent these issues and improve sensitivity.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oleg Pokrovskiy, Irina Rostovschikova, Konstantin Ustinovich, Ilya Voronov, Dmitry Kosyakov
Summary: A chromatography-like propagation of water through the material bed was observed during supercritical fluid extraction of aroma plants with high moisture content, which could be significant for modeling the kinetics of supercritical fluid extraction of non-volatile compounds.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Yasar Kemal Recepoglu, Ozguer Arar, Asli Yuksel
Summary: Biosorption using phosphorylated hazelnut shell waste (FHS) is a promising method for lithium removal and recovery. This study investigated the performance of a continuous-flow packed-bed column system using FHS for ultra-low level lithium removal. The results showed that the lihium biosorption capacity of the FHS column was unaffected by the bed height, but decreased with increasing flow rate.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Jian Sun, Zheheng Zheng, Zixiao Jia, Jiabin Wang, Xucong Lin
Summary: In this study, an ionic covalent organic framework (iCOF) surface grafting monolithic sorbent was prepared for in-tube solid-phase microextraction (SPME) of aristolochic acids (AAs) in various samples. The density of quaternary ammonium ions in the iCOF was modulated for enhanced adsorption of AAs. The iCOF surface grafting monolithic sorbent was confirmed by different means. Several operating conditions were optimized to develop the online in-tube SPME-HPLC method, which showed good linearity, low limits of detection, and high recoveries for AAs in serum samples. This study presents a feasible approach for the application of COF-based monolithic sorbents in sample preparation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zeng Wen, Ruihan Peng, Die Gao, Jing Lin, Jia Zeng, Zhou Li, Famin Ke, Zhining Xia, Dandan Wang
Summary: A chitosan-alginate sponge with multiple cross-linking networks was developed for adsorption and enrichment of anionic dyes from food samples. The sponge showed better three-dimensional network structure, mechanical behavior, and stability compared to pure chitosan and alginate sponges. The adsorption performance and selectivity of the sponge were systematically studied, and it maintained high adsorption capacity and selectivity for anionic dyes. The sponge also showed satisfactory reusability and was successfully combined with high-performance liquid chromatography for the enrichment and detection of anionic dyes in candy and cocktail samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Hairong Zhang, Xiaojuan Jiang, Dandan Zhang, Yuexin Yang, Qiang Xie, Caisheng Wu
Summary: Analysis of in vivo exposure to traditional Chinese medicine using mass spectrometry is helpful for identifying effective ingredients and developing new drugs. This study focused on Forsythia suspensa (Lian Qiao) and used metabolomics technology to explore its in vivo exposure. By comparing the differences before and after administration, a complete set of nontargeted analysis strategies for TCM exposure was established. The study identified 393 Lian Qiao-related chemical components in mice after administration, including prototypes and metabolites. This study provides a reference for research on the active ingredients of Lian Qiao in vivo.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oscar Castejon-Musulen, Ricardo Lopez, Ignacio Ontan, Vicente Ferreira
Summary: A quantitative analytical method was developed and validated in this study to determine the concentrations of 81 aroma-relevant wine volatiles. The method utilizes stir bar sorptive extraction and multidimensional gas chromatography with flame ionization detector or mass spectrometer. The method demonstrated good linearity, reproducibility, and recovery, and was successfully applied to analyze 20 wine samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)
