Article
Chemistry, Multidisciplinary
Timo Stuenkel, Kathrin Siebold, Daichi Okumatsu, Kazuki Murata, Louise Ruyet, Constantin G. Daniliuc, Ryan Gilmour
Summary: The regio- and enantio-selective dearomatization of phenols has been achieved using I(i)/I(iii) catalysis enabled fluorination. The reaction is highly selective and efficient, offering great potential in the field of hydroxylation chemistry.
Article
Biochemistry & Molecular Biology
Yingbi Chen, Jiali Tang, Shixing Wang, Libo Zhang
Summary: A chitosan-based adsorbent, CS-Ninhydrin, was synthesized for efficient adsorption of Pb(II) ions, showing good removal rate and selectivity under various conditions. The adsorption mechanism involves chelating and electrostatic interactions between N and O groups in CS-Ninhydrin and Pb(II) ions, promoting the widespread application of chitosan in Pb(II) adsorption.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Analytical
D. B. Petrenko, D. Yu. Marchenko, N. V. Vasil'ev
Summary: A new photometric procedure has been developed for the determination of fluoride ion based on its destruction of zirconiumgallocyanin MS complex. The method shows high selectivity towards fluoride and a linear range for quantitative determination. No preliminary separation of matrix components is required, making it suitable for analyzing fluoride in various complex samples.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Zheng-Jia Shen, Chen Zhu, Xiao Zhang, Chao Yang, Magnus Rueping, Lin Guo, Wujiong Xia
Summary: This article describes a selective (deutero)hydrodefluorination reaction via electrolysis, which achieves remarkable chemoselectivity control by the addition of different organoboron sources. The method is operationally simple, scalable, and provides access to high-value building blocks for medicinal chemistry in one step.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Mohamed A. Abdel-Lateef, Albandary Almahri
Summary: This study presents a comprehensive analytical protocol for investigating the fluorescence properties of DFMO, providing accurate determination of DFMO under carefully optimized reaction conditions. The suggested approach showed unique selectivity for DFMO determination in commercial cream samples and human urine specimens, with satisfactory recovery results.
Article
Engineering, Chemical
Wanjia Zhang, Liming Tao, Luobing Xun, Zhongxu Qi, Stephen Pooley, Wei Sun, Jian Cao, Zhiyong Gao
Summary: Pullulan polysaccharide (PU) has been evaluated as a potential depressant in the flotation separation of molybdenite from talc, showing effective results under the reagent scheme of 40 mg/L PU, 160 mg/L butyl xanthate (BX), and 25 mu L/L MIBC. FTIR and XPS analyses demonstrate that BX can desorb the pre-adsorbed PU on the surface of the molybdenite by competitive adsorption, highlighting the potential for industrial application in the flotation separation of molybdenite from talc.
MINERALS ENGINEERING
(2022)
Article
Chemistry, Organic
Yinxiang Jian, Peng Liang, Xiaoyan Li, Huawu Shao, Xiaofeng Ma
Summary: This study presents an efficient and highly functional group-compatible procedure for the controllable transformation of indoles. By controlling the amounts of reactants, different products can be obtained. The advantages of this method include mild conditions, short reaction time, high yields, and the use of an air- and moisture-stable catalyst.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2022)
Article
Biochemical Research Methods
Gerrit Haeger, Johannes Bongaerts, Petra Siegert
Summary: An improved and convenient ninhydrin assay for aminoacylase activity measurements was developed using the commercial EZ NinTM reagent. The addition of DMSO enhanced the solubility of Ruhemann's purple, and the use of a basic, aqueous buffer improved its stability. Furthermore, an acidic protocol for quantification of lysine was developed. The assay allows for parallel processing in a 96-well format.
ANALYTICAL BIOCHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Minjae Kim, Bohyun Park, Minkyeong Shin, Suyeon Kim, Junghoon Kim, Mu-Hyun Baik, Seung Hwan Cho
Summary: A copper-catalyzed enatiotopic-group-selective allylation of gem-diborylalkanes with allyl bromides was reported in this study. The combination of copper(I) bromide and H-8-BINOL derived phosphoramidite ligand proved to be the most effective catalytic system, providing various enantioenriched homoallylic boronate esters under mild conditions. Experimental and theoretical studies elucidated the reaction mechanism and revealed the enatiotopic-group-selective trans-metalation of gem-diborylalkanes with chiral copper complex.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Spectroscopy
Mona Saad Binkadem, Huda Salem AlSalem, Soha Talal Al-Goul, Wejdan T. Alsaggaf, Mohamed A. El Hamd, Mohamed A. Abdel-Lateef
Summary: In this study, two spectrofluorimetric approaches were developed to activate the fluorescence activity of Netilmicin (NTC), an antibiotic used to treat infections caused by a broad range of Gram-negative and Gram-positive bacteria. The pharmaceutically formulated ophthalmic dosage forms were used in the study.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Metallurgy & Metallurgical Engineering
Zhiyong Gao, Jian Deng, Wei Sun, Jianjun Wang, Yunfeng Liu, Fengping Xu, Qinghong Wang
Summary: In this study, scheelite and calcite were selectively separated using 2-phosphonobutane-1, 2, 4-tricarboxylic acid (PBTCA) as a novel depressant. The results showed that PBTCA effectively depressed calcite, achieving the desired flotation effect. This research has significant industrial application potential in the separation of calcium minerals and water treatment.
MINERAL PROCESSING AND EXTRACTIVE METALLURGY REVIEW
(2022)
Article
Chemistry, Multidisciplinary
Victor Laserna, Daniel Abegg, Claudia F. Afonso, Esther M. Martin, Alexander Adibekian, Peter Ravn, Francisco Corzana, Goncalo J. L. Bernardes
Summary: This study presents maleic-acid derivatives as robust cysteine-selective reagents for protein labelling, showing high efficiency and stability compared to maleimides. By introducing chlorine atoms, these derivatives can form conjugates resistant to retro-Michael reactions, which is significant for environments with biological thiols and human plasma.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Biochemistry & Molecular Biology
Wioletta Parys, Alina Pyka-Pajak
Summary: This study developed a selective and accurate TLC-densitometric method for the determination of valproic acid in a drug. Different visualizing reagents were used, and the method showed good linearity, accuracy, and precision. It can be applied for routine analysis of valproic acid in pharmaceutical formulations.
Article
Spectroscopy
Saranya Gopalakrishnan, Rajesh Ghosh, T. Renganathan, S. Pushpavanam
Summary: Triclosan, a commonly used biocide, can be selectively determined through azo-coupling reaction at pH 7.2 without interference from other phenolic compounds. The developed analytical model allows for simultaneous determination of triclosan and naphthol with good sensitivity and linear calibration plot. Solid-phase extraction enhances detection of triclosan in water samples with a high average relative recovery rate.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Biochemical Research Methods
Nuanlaor Ratanawimarnwong, Vanlada Suksomphot, Khemika Sornpipatpong, Supamit Lengwan, Suchao Donpudsa, Nuthawut Choengchan, Thitirat Mantim
Summary: This paper presents a microfludic device for the determination of sucrose using Benedict's test. By modifying a laboratory filter paper, a unique hydrophobic barrier was created, allowing for the measurement of sucrose and reducing sugars. The device was simple to use, requiring only basic laboratory equipment and a smartphone to capture the results. The method showed good linearity and low standard deviation for sucrose measurement.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Biochemical Research Methods
Azza H. Rageh, Ute Pyell
Article
Chemistry, Analytical
Azza H. Rageh, Sherien A. Abdel-Rahim, Hassan F. Askal, Gamal A. Saleh
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2019)
Article
Spectroscopy
Aya M. Mostafa, Azza H. Rageh, Marwa F. B. Ali, Fardous A. Mohamed
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2019)
Article
Pharmacology & Pharmacy
Noha N. Atia, Hesham M. Tawfeek, Azza H. Rageh, Marwa R. El-Zahry, Ahmed Abdelfattah, Mahmoud A. Younis
SAUDI PHARMACEUTICAL JOURNAL
(2019)
Article
Biochemical Research Methods
Fardous A. Mohamed, Marwa F. B. Ali, Azza H. Rageh, Aya M. Mostafa
BIOMEDICAL CHROMATOGRAPHY
(2019)
Article
Chemistry, Analytical
Fardous A. Mohamed, Marwa F. B. Ali, Azza H. Rageh, Aya M. Mostafa
MICROCHEMICAL JOURNAL
(2019)
Article
Chemistry, Analytical
Sameh Ahmed, Noha N. Atia, Azza H. Rageh
Article
Chemistry, Analytical
Abdel-Maaboud I. Mohamed, Azza H. Rageh, Fatma A. M. Abdel-aal, Al-Montaser Bellah H. Ali
Article
Biochemical Research Methods
Azza H. Rageh, Fatma A. M. Abdel-aal, Ute Pyell
JOURNAL OF CHROMATOGRAPHY A
(2020)
Article
Chemistry, Analytical
Mohamed I. Said, Fatma A. M. Abdel-aal, Azza H. Rageh
MICROCHEMICAL JOURNAL
(2020)
Article
Biochemical Research Methods
Pakinaz Y. Khashaba, Azza H. Rageh, Noha N. Atia, Sally A. El Zohny
Summary: In this study, a fast, versatile, and convenient DSPME method combined with a spectro-densitometric technique was developed for the analysis of zolmitriptan in biological fluids. The method showed good adsorption capability, selectivity, and accuracy in quantifying trace levels of ZOLM.
JOURNAL OF CHROMATOGRAPHY A
(2021)
Article
Chemistry, Analytical
Al-Montaser Bellah H. Ali, Fatma A. M. Abdel-aal, Azza H. Rageh, Abdel-Maaboud Mohamed
Summary: Avanafil is a new PDE-5 inhibitor used for treating erectile dysfunction, often coadministered with antihypertensive drugs like Nimodipine. A new electrochemical method using nanoparticle-modified electrodes was developed to simultaneously determine the levels of Avanafil and Nimodipine in human serum samples. The study found that coadministration of Avanafil and Nimodipine may lead to a significant increase in Avanafil serum concentration, highlighting the importance of dose adjustment when these drugs are used together.
MICROCHEMICAL JOURNAL
(2022)
Article
Biochemical Research Methods
A. Sherien Farrag, H. Azza Rageh, F. Hassan Askal, A. Gamal Saleh
Summary: This study aimed to explore the application of ionic liquid-coated nanoparticles in the separation and pre-concentration of highly hydrophilic analytes. The method was successfully validated for the extraction and determination of the antibiotic cefoperazone. Under optimized conditions, the developed approach showed good linearity, sensitivity, and recovery.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2022)
Article
Chemistry, Analytical
Al-Montaser Bellah H. Ali, Fatma A. M. Abdel-Aal, Azza H. Rageh, Abdel-Maaboud Mohamed
Summary: Diabetes is a risk factor for sexual dysfunction in men, specifically increasing the risk of erectile dysfunction. Canagliflozin is a commonly used antidiabetic drug for type-2 diabetes and can be combined with phosphodiesterase 5 inhibitors to alleviate erectile dysfunction. This study developed a high-performance thin-layer chromatographic method to simultaneously determine the concentrations of tadalafil and canagliflozin in human plasma and demonstrated a significant interaction between the two drugs when administered simultaneously.
JOURNAL OF SEPARATION SCIENCE
(2022)
Article
Chemistry, Analytical
Al-Montaser Bellah H. Ali, Azza H. Rageh, Fatma A. M. Abdel-aal, Abdel-Maaboud I. Mohamed
Summary: Patients receiving anticancer drugs may experience loss of sexual desire and erectile dysfunction as adverse effects. It is important to recognize possible pharmacokinetic interactions when administering drugs to cancer patients. A sensitive sensor using carbon paste electrode modified with titanium dioxide nanoparticles and multi-walled carbon nanotubes was designed for the simultaneous determination of the anticancer drug avanafil and doxorubicin in rabbit plasma samples. The modified electrode showed improved sensitivity and separation between the oxidation peaks of AVN and DOX. The method was effective for analyzing AVN in real rabbit plasma samples and monitoring the possible pharmacokinetic interactions between AVN and DOX.
MICROCHEMICAL JOURNAL
(2023)
