Structural modeling and patch-clamp analysis of pain-related mutation TRPA1-N855S reveal inter-subunit salt bridges stabilizing the channel open state

Published 2015 View Full Article

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Title
Structural modeling and patch-clamp analysis of pain-related mutation TRPA1-N855S reveal inter-subunit salt bridges stabilizing the channel open state
Authors
Keywords
Ankyrin receptor subtype 1, Transient receptor potential, S4–S5-linker, Mutagenesis, Homology modeling, Molecular dynamics
Journal
NEUROPHARMACOLOGY
Volume 93, Issue -, Pages 294-307
Publisher
Elsevier BV
Online
2015-02-25
DOI
10.1016/j.neuropharm.2015.02.018

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