Article
Environmental Sciences
Krishna Kumar Jaiswal, Vinod Kumar, Neha Arora, Mikhail S. Vlaskin
Summary: Phenolic compounds, which can contaminate water and harm the ecosystem, can be efficiently degraded by the enzymes in microalgae. In this study, Chlorella sorokiniana was cultured under the influence of phenol and p-nitrophenol, resulting in a significant reduction in their concentrations. The degradation process also led to the accumulation of lipids in the microalgae, indicating the potential for biodiesel production.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Environmental Sciences
Krishna Kumar Jaiswal, Vinod Kumar, Mikhail S. Vlaskin, Manisha Nanda
Summary: Pyrene, an anthropogenic pollutant, was used to evaluate the inhibitory effect on Chlorella sorokiniana. Despite a slight decrease in biomass generation under pyrene stress, lipid biosynthesis was induced, leading to a 24% increase in lipid production, facilitating the production of renewable biodiesel.
Article
Agronomy
Prachi Nawkarkar, Vikas U. Kapase, Sarika Chaudhary, Sachin Kajla, Shashi Kumar
Summary: Algae have been utilized for their potential in renewable energy, nutraceuticals, and value-added products. However, low lipid yield is a major challenge for the commercial use of algae. This study successfully introduced the BnDGAT gene into a fast-growing and thermotolerant strain of Chlorella sorokiniana, resulting in increased intracellular lipid accumulation. The expression of BnDGAT led to higher levels of non-polar lipids and polyunsaturated fatty acids, demonstrating the potential of genetic engineering to improve algae's nutritional value and lipid productivity.
GLOBAL CHANGE BIOLOGY BIOENERGY
(2023)
Article
Engineering, Environmental
Dokyung Kim, Yooeun Chae, Minjin Kim, Youn-Joo An
Summary: This study investigated the impact of ethylenediaminetetraacetic acid (EDTA) on the toxicity of boron to the algae species Chlamydomonas reinhardtii, Chlorella sorokiniana, and Chlorella vulgaris. C. vulgaris was the least sensitive to boron in the presence of EDTA, while C. reinhardtii and C. sorokiniana exhibited high sensitivity. The chelation of EDTA with micronutrients reduced their availability for uptake by the algae, leading to increased sensitivity to boron. These findings have implications for assessing and managing boron risk in aquatic ecosystems.
JOURNAL OF WATER PROCESS ENGINEERING
(2023)
Article
Engineering, Chemical
Kuan Shiong Khoo, Yen Mun Chong, Wen Sing Chang, Jie Min Yap, Su Chern Foo, Ianatul Khoiroh, Phei Li Lau, Kit Wayne Chew, Chien Wei Ooi, Pau Loke Show
Summary: CO2-based alkyl carbamate ILs were proposed as an alternative solvent for lutein extraction from Chlorella sorokiniana. Complete separation of lutein from ILs was achieved by distillation under mild conditions, and the recyclability of DPCARB was found to be satisfactory after multiple cycles of extraction. The potential of CO2-based alkyl carbamate ILs in lutein extraction is promising due to their recyclability, which helps reduce environmental impact and operating costs.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Plant Sciences
Maria Morales-Pineda, Maria Elena Garcia-Gomez, Rodrigo Bedera-Garcia, Mercedes Garcia-Gonzalez, Inmaculada Couso
Summary: High concentrations of CO2 promote growth and photosynthetic capacity in Chlorella strains, and also affect the levels of signaling molecules, inositol polyphosphates, which impact cell signaling and energy levels. Further investigation of the connections between carbon assimilation and cell signaling by polyphosphate inositols in microalgae is important for optimizing their biotechnological applications.
Article
Biotechnology & Applied Microbiology
Hiroki Yoshida, Sabine van Oossanen, Maria J. Barbosa, Marcel Janssen
Summary: In this study, the short-term photosynthetic response of suspended Chlorella sorokiniana to limiting light intensity and CO2 concentration was investigated using a novel CO2-based photosynthesis monitor. The results showed that light intensity had a significant impact on photosynthesis, while CO2 limitation severely affected the efficiency of photosynthesis.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2023)
Article
Energy & Fuels
B. Namitha, Asha Sathish, P. Senthil Kumar, K. Nithya, Shyam Sundar
Summary: This study compared the performance of Monoraphidium sp. and Chlorella sorokiniana in the energy conversion process, finding that Chlorella sorokiniana has higher yield and more favorable fatty acid profile. The use of biodiesel showed high lipid recovery and lower CO and HC emissions, but slightly higher nitrogen oxides and carbon dioxide emissions.
Article
Agricultural Engineering
Cam Van T. Do, Cuc T. Dinh, Mai T. Dang, Thuan Dang Tran, Truong Giang Le
Summary: The novel flat-panel photobioreactor (FPP) was effectively demonstrated in maximizing the efficiency of microalgae in fixing CO2 and producing biomass and lutein in this study.
BIORESOURCE TECHNOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Manisha Nanda, Krishna Kumar Jaiswal, Vinod Kumar, Mikhail S. Vlaskin, Pankaj Gautam, Vivekanand Bahuguna, P. K. Chauhan
Summary: Green oleaginous microalgae are promising candidates for the integration of heavy metal bioremediation with biofuel production. In this study, Chlorella sorokiniana was used for lead mitigation and biodiesel production, showing high tolerance to lead exposure and altered lipid profiles under stress conditions. This research provides valuable insights into the potential applications of oleaginous microalgae in environmental remediation and sustainable biofuel production.
ENVIRONMENTAL TECHNOLOGY & INNOVATION
(2021)
Article
Energy & Fuels
MubarakAli Davoodbasha, Arivalagan Pugazhendhi, Jung-Wan Kim, Sang-Yul Lee, Thajuddin Nooruddin
Summary: The study achieved successful conversion of algal oil into biodiesel using CaO nanocatalyst, and optimized the process by adjusting reaction parameters and catalyst concentration.
Article
Environmental Sciences
Abdul Hai Alami, Shamma Alasad, Mennatalah Ali, Maitha Alshamsi
Summary: Carbon capture and sequestration technologies, such as using algae to absorb CO2 and convert it into biomass, are promising for reducing carbon emissions and producing biodiesel. The performance of these biosystems depends on various conditions, and different steps are involved in producing biodiesel from algae.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Energy & Fuels
Daniel A. Alfaro-Sayes, Jerome Amoah, Nova Rachmadona, Shinji Hama, Tomohisa Hasunuma, Akihiko Kondo, Chiaki Ogino
Summary: The aim of this study was to evaluate the effect of alginate immobilization on the growth and lipid productivity of the microalgae Chlorella sorokiniana. The results showed that immobilization technology can enhance the growth and lipid productivity of microalgae.
JOURNAL OF PHYSICS-ENERGY
(2023)
Article
Agricultural Engineering
Cecilia Naveira-Pazos, Maria C. Veiga, Christian Kennes
Summary: This study demonstrates that a mixture of VFAs obtained from acetogenic bacteria can be used in aerobic fermentation with Yarrowia lipolytica to produce lipids as precursors for biodiesel. Acetic acid is the preferred substrate for Yarrowia lipolytica, with a high consumption rate for lipid production.
BIORESOURCE TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Aline C. C. Pena, Lucas Manique Raymundo, Luciane F. Trierweiler, Mariliz Gutterres
Summary: In this study, microalgae biochar was used to synthesize carbon dots (CDs) for detecting toxic metal ions. The synthesized CDs showed high fluorescence intensity and stability. The results demonstrated selective quenching ability of the CDs towards Cr (VI), indicating their potential for metal ion detection.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2023)
Article
Multidisciplinary Sciences
Zhongqiang Li, Yoshita Holamoge, Zheng Li, Waleed Zaid, Michelle L. Osborn, Alexandra Ramos, Jacob T. Miller, Yanping Li, Shaomian Yao, Jian Xu
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
(2020)
Article
Engineering, Biomedical
Zhongqiang Li, Alexandra Ramos, Zheng Li, Michelle L. Osborn, Xin Li, Yanping Li, Shaomian Yao, Jian Xu
Summary: This study introduces an optimized JPEG-XT method, which enhances the compression of 16-bit depth medical images by amplifying DCT coefficients. The results indicate the significance of integer and decimal portions of DCT coefficients in image compression. The method enables lossless compression of medical images while reducing storage space.
BIOMEDICAL SIGNAL PROCESSING AND CONTROL
(2021)
Article
Dentistry, Oral Surgery & Medicine
P. Kongthitilerd, A. Sharma, H. E. Guidry, W. Rong, J. Nguyen, S. Yao, S. Adisakwattana, H. Cheng
Summary: The study revealed that ADH inhibits osteogenesis in dental follicle stem cells by activating V1a receptors and the PLC-IP3 pathway to stimulate intracellular calcium signals. The inhibitory effect of ADH can be reversed by drugs like V2255, and the calcium signaling pathway can be intervened by inhibiting specific components like PLC and IP3 receptors.
ARCHIVES OF ORAL BIOLOGY
(2021)
Article
Anatomy & Morphology
Weiqiong Rong, Calvin Rome, Shaomian Yao
Summary: This study found that miR-7a-5p and miR-592 are upregulated during the expansion of dental pulp stem cells (DPSCs) and regulate osteogenic differentiation through TNF, MAPK, and PI3K-Akt pathways. These findings are significant for maintaining the osteogenic potential of stem cells and treating bone regeneration and bone-related diseases.
CELLS TISSUES ORGANS
(2022)
Article
Engineering, Electrical & Electronic
Zheng Li, Zhongqiang Li, Yoshita V. Holamoge, Waleed Zaid, Michelle L. Osborn, Shradha Bhatta, Abhirami Jeyaseelan, Yanping Li, Shaomian Yao, Jian Xu
Summary: The study demonstrated the effectiveness of a new near-infrared dental fluorescence imaging system with mouthwash administration of indocyanine green (ICG) for improved image contrast, particularly in unerupted molars. The method offered lower dosage, convenience, and quick results, making it a cost-effective and safe tool for diagnosing dental diseases.
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS
(2021)
Article
Computer Science, Artificial Intelligence
Zhongqiang Li, Zheng Li, Qing Chen, Alexandra Ramos, Jian Zhang, J. Philip Boudreaux, Ramcharan Thiagarajan, Yvette Bren-Mattison, Michael E. Dunham, Andrew J. McWhorter, Xin Li, Ji-Ming Feng, Yanping Li, Shaomian Yao, Jian Xu
Summary: This study developed a lab-designed Raman spectroscopic system combined with a convolutional neural network model to efficiently distinguish pancreatic cancer tissue, achieving high performance and opening up new possibilities for intraoperative diagnosis.
Article
Medicine, Research & Experimental
Phutthida Kongthitilerd, Thavaree Thilavech, Marisa Marnpae, Weiqiong Rong, Shaomian Yao, Sirichai Adisakwattana, Henrique Cheng, Tanyawan Sauntawee
Summary: C3R stimulates insulin secretion by promoting Ca2+ influx via VDCCs and activating the PLC-IP3 pathway. It also upregulates the expression of genes necessary for glucose-induced insulin secretion.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Letter
Oncology
Zhongqiang Li, Zheng Li, Alexandra Ramos, J. Philip Boudreaux, Ramcharan Thiagarajan, Yvette Bren Mattison, Michael E. Dunham, Andrew J. McWhorter, Qing Chen, Jian Zhang, Ji-Ming Feng, Yanping Li, Shaomian Yao, Jian Xu
CANCER COMMUNICATIONS
(2021)
Article
Biology
Zheng Li, Zhongqiang Li, Qing Chen, Jian Zhang, Michael E. Dunham, Andrew J. McWhorter, Ji-Ming Feng, Yanping Li, Shaomian Yao, Jian Xu
Summary: Early detection of laryngeal cancer is crucial for survival rates, treatment options, and healthcare costs. A non-invasive optical biopsy for laryngeal carcinoma can improve early detection and monitoring, as well as improve margin control during surgery. In this study, a Raman spectroscopy system was evaluated for rapid intraoperative detection of human laryngeal carcinoma, using different spectral analysis methods. Results showed that the convolutional neural network method demonstrated the highest performance in terms of accuracy, sensitivity, and specificity.
COMPUTERS IN BIOLOGY AND MEDICINE
(2022)
Article
Biochemical Research Methods
Zhongqiang Li, Zheng Li, Waleed Zaid, Michelle L. Osborn, Yanping Li, Shaomian Yao, Jian Xu
Summary: This study demonstrates the feasibility of using indocyanine green-assisted near-infrared fluorescence dental imaging, which can provide good imaging results for both erupted and unerupted teeth structures at different NIR wavelengths.
JOURNAL OF BIOMEDICAL OPTICS
(2022)
Article
Plant Sciences
Juan D. Montenegro, Irene Julca, Lenin D. Chumbe-Nolasco, Lila M. Rodriguez-Perez, Ricardo Sevilla Panizo, Alicia Medina-Hoyos, Dina L. Gutierrez-Reynoso, Juan Carlos Guerrero-Abad, Carlos A. Amasifuen Guerra, Aura L. Garcia-Serquen
Summary: Peru is an important center for maize diversity, and purple maize is a highly appreciated variety by the local populations. The origin of Peruvian purple maize is believed to be from different ancestral gene pools with recurrent gene flow from wild relatives. These findings provide valuable insights into the evolution and domestication of maize in South America.
Article
Medicine, Research & Experimental
Phutthida Kongthitilerd, Elise Barras, Weiqiong Rong, Ansleigh Thibodeaux, Madison Rigdon, Shaomian Yao, Sirichai Adisakwattana, Tanyawan Suantawee, Henrique Cheng
Summary: The objective of this study was to elucidate the mechanism of cyanidin, the most abundant anthocyanin found in red-purple plants, in inhibiting adipocyte formation. The results demonstrated that cyanidin inhibits adipogenesis by activating the PLC-IP3 pathway and intracellular Ca2+ signaling. This study provides new insights into the anti-obesity effect of cyanidin.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Cell Biology
Weiqiong Rong, Calvin P. Rome, Marilyn A. Dietrich, Shaomian Yao
Summary: This study found that human mesenchymal stem cells (hMSCs) lose their osteogenic differentiation potential during in vitro expansion, which limits their clinical applications. The downregulation of CRISPLD2 was identified as a key factor contributing to this loss of osteogenic capacity in hMSCs. Knockdown of CRISPLD2 inhibited the osteogenic differentiation of hMSCs, while overexpression of CRISPLD2 partially rescued the impaired differentiation. CRISPLD2 may serve as a potential therapeutic target for bone-related diseases.
JOURNAL OF CELLULAR PHYSIOLOGY
(2023)
Article
Engineering, Biomedical
Zheng Li, Zhongqiang Li, Yuting Yang, Shaomian Yao, Chaozheng Liu, Jian Xu
Summary: Medical diagnosis heavily relies on bio-imaging techniques, such as the use of ICG-based biological sensors for fluorescence imaging. This study aimed to improve the fluorescence signals of ICG-based sensors by incorporating liposome-modified ICG. The results showed that MLM-ICG had the best properties among the samples tested, with higher fluorescence intensity and stability. This suggests that incorporating liposome-modified ICG in fluorescence spectroscopy could be an effective way to develop novel biosensors for disease diagnosis.
LASERS IN MEDICAL SCIENCE
(2023)
Article
Agriculture, Dairy & Animal Science
Savina A. Gutierrez-Calle, Rosa A. Sanchez-Diaz, Yolanda B. Delgado-Silva, Juan D. Montenegro, Dina L. Gutierrez, Jorge L. Maicelo-Quintana, Juan C. Guerrero-Abad
Summary: Natural resistance to coffee leaf rust has been identified in wild species Coffea canephora and Coffea liberica. Interspecific resistant hybrids have been generated through breeding programs using these species.
SCIENTIA AGROPECUARIA
(2021)