Article
Clinical Neurology
Isabelle Lambert, Nicolas Roehri, Julie Fayerstein, Bernard Giusiano, Bruno Colombet, Christian-George Benar, Fabrice Bartolomei
Summary: This study investigated changes in thalamo-cortical and cortico-cortical connectivity during different sleep stages using stereoelectroencephalography (SEEG) recordings in humans. The results showed stronger connectivity between the thalamus and other brain regions during N2 and REM sleep compared to N3 sleep, while N3 sleep exhibited stronger cortico-cortical connectivity. The thalamus played a driving role in thalamo-insular connectivity during REM sleep.
CLINICAL NEUROPHYSIOLOGY
(2022)
Article
Neurosciences
Manoj K. Eradath, Mark A. Pinsk, Sabine Kastner
Summary: The pulvinar nucleus in the thalamus plays a significant role in regulating information transmission between cortical areas, maintaining functional connectivity across networks. Inactivation of a part of the pulvinar led to reduced neural activity synchronization between interconnected cortical nodes. These findings suggest a causal role for the pulvinar in synchronizing neural activity within a large-scale network.
JOURNAL OF COMPARATIVE NEUROLOGY
(2021)
Article
Neurosciences
Antonin Blot, Morgane M. Roth, Ioana Gasler, Mitra Javadzadeh, Fabia Imhof, Sonja B. Hofer
Summary: Research shows that responses of mouse LP neurons mainly derive from feedforward inputs from V1, combined with information from multiple brain regions. Signals from LP projections to different higher visual areas are tuned to specific features of visual stimuli and their locomotor context.
Article
Clinical Neurology
Marina Luisa Rodocanachi Roidi, Francesca Cozzi, Ioannis Ugo Isaias, Francesca Grange, Elena Paola Ferrari, Enrico Ripamonti
Summary: This study aims to identify clinical features associated with the presence and severity of scoliosis in girls with Rett syndrome. Multivariable analysis revealed that the severity of scoliosis is correlated with age, neurological factors such as muscular hypertonus and hyperreflexia, as well as locomotor impairments. The findings highlight the importance of monitoring scoliosis in conjunction with motor impairments in patients with Rett syndrome.
EUROPEAN SPINE JOURNAL
(2022)
Article
Neurosciences
Bruno Oliveira Ferreira de Souza, Eve-Marie Frigon, Robert Tremblay-Laliberte, Christian Casanova, Denis Boire
Summary: The study examined the distribution of cortical thalamic neurons projecting to the pulvinar nucleus in the thalamus in cats and mice, revealing that in cats these neurons were mainly located in Layer 6 except in Area 17 where they were in Layer 5, while in mice they were predominantly found in Layer 6 across all areas. The findings suggest that corticothalamic projections in mice do not follow the same organization as in cats, indicating distinct roles of transthalamic pathways in these species.
JOURNAL OF COMPARATIVE NEUROLOGY
(2021)
Article
Neurosciences
Carole Guedj, Patrik Vuilleumier
Summary: Selective attention mechanisms amplify relevant sensory information while suppressing interference. The pulvinar, a nucleus of the thalamus with unique connectivity pattern, plays a crucial role in coordinating cortical activity during selective attention. Our study revealed distinct modulations of pulvinar activity and connectivity during the co-occurrence of task-relevant and task-irrelevant but salient stimuli.
Review
Behavioral Sciences
Giacomo Guidali, Camilla Roncoroni, Nadia Bolognini
Summary: Research has reviewed recent advances in using non-invasive brain stimulation protocols, proposing a new classification scheme and describing their characteristics and application in studying and promoting brain plasticity. It is concluded that these protocols represent promising tools for studying human sensorimotor and crossmodal network plasticity.
BEHAVIOURAL BRAIN RESEARCH
(2021)
Article
Behavioral Sciences
Angela W. Huang, Anita D. Barber
Summary: The study investigated the role of the lateral pulvinar nucleus (LPN) in visual attention and its development throughout late childhood to early adulthood. The findings revealed changes in LPN functional connectivity with visual processing regions, as well as the association between LPN connectivity patterns and attention deficits, particularly in Attention Deficit Hyperactivity Disorder (ADHD). The results suggest that LPN connectivity with higher order attention networks plays a crucial role in attention abilities.
Article
Endocrinology & Metabolism
Juliana Cristina Romero Rojas-Ramos, Julita Maria Pelaez, Sergio Eiji Ono, Cassio Slompo Ramos, Arnolfo de Carvalho Neto, Luiz de Lacerda, Suzana Nesi-Franca
Summary: This study evaluated cortical thickness (CT) abnormalities in adolescents with congenital hypothyroidism (CH) detected by neonatal screening (NS) program in Paraná, Brazil. The results showed morphometric alterations in the cerebral cortex of CH patients compared to healthy controls, and CT was significantly correlated with cognitive level and variables of neurocognitive prognosis.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Biology
Vinod Jangir Kumar, Christian F. Beckmann, Klaus Scheffler, Wolfgang Grodd
Summary: Nearly all processing in the cortex depends strongly on interactions with the thalamus, but the functional interactions between the human thalamus nuclei and the cerebral cortex are still not fully understood. This study examines the connectivity and mapping of different thalamic nuclei with cortical networks, revealing intertwined functional associations and suggesting that relay-specific thalamic nuclei are involved in higher-order functions as well. The findings contribute to our understanding of the interactions between cortical networks and the thalamus, which may be of interest to researchers in neuroscience and clinical fields.
COMMUNICATIONS BIOLOGY
(2022)
Article
Physics, Multidisciplinary
Giordano De Marzo, Giulio Iannelli
Summary: This paper studies the impact of spatial correlations on the retrieval capability of the Hopfield network at null temperature. By using configurations of a linear Ising model as stored patterns, the analysis is limited to exponentially decaying spatial correlations. Using the signal to noise technique, a phase diagram is obtained in the load of the Hopfield network and the Ising temperature, showing a fuzzy phase and a retrieval region. Interestingly, increasing the spatial correlation inside patterns decreases the critical load of the Hopfield network, a result confirmed by numerical simulations. The analysis is then extended to Dense Associative Memories with arbitrary odd-body interactions, obtaining analogous results.
PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS
(2023)
Article
Ophthalmology
Manjot Kaur Grewal, Shruti Chandra, Sarega Gurudas, Rajna Rasheed, Piyali Sen, Deepthy Menon, Alan Bird, Glen Jeffery, Sobha Sivaprasad
Summary: In this study, functional and structural correlations in AMD patients, particularly focusing on subretinal drusenoid deposits (SDD), were evaluated. Patients with SDD showed impaired visual acuity and scotopic function, along with delayed rod-intercept time (RIT) compared to controls and AMD patients without SDD. Functional parameters were closely associated with retinal structure, suggesting the importance of evaluating potential prophylactic agents and different therapeutic interventions in AMD patients with SDD.
Article
Neurosciences
Xiao-Jun Xiang, Sheng-Qiang Chen, Xue-Qin Zhang, Chang-Hui Chen, Shun-Yu Zhang, Hui-Ru Cai, Song-Lin Ding
Summary: This study has discovered a possible equivalent of the primate posterior cingulate cortex (A23) in rodents, which can aid in modeling related circuits and diseases in these animals.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Clinical Neurology
Francesca Pizzo, Nicolas Roehri, Bernard Giusiano, Stanislas Lagarde, Romain Carron, Didier Scavarda, Aileen McGonigal, Cristina Filipescu, Isabelle Lambert, Francesca Bonini, Agnes Trebuchon, Christian-George Benar, Fabrice Bartolomei
Summary: In this study, it was found that thalamic involvement during seizures is common in different seizure types, with a significant effect of thalamic epileptogenicity on postsurgical outcome. Moreover, basal ganglia may also show high values of epileptogenicity, although to a lesser degree than the thalamus.
Article
Neurosciences
Vincent Bazinet, Reinder Vos de Wael, Patric Hagmann, Boris C. Bernhardt, Bratislav Misic
Summary: Signaling in brain networks occurs across multiple topological scales, with different brain regions showing preferences for local or global communication. Unimodal regions prefer local communication, while multimodal regions prefer global communication. These communication preferences result in region- and scale-specific structure-function coupling, contributing to the functional diversity observed in the brain.