Article
Thermodynamics
P. Yadhi Cruz, A. Miguel Esteso, M. Carmen Romero
Summary: This study provides new and important information on the apparent molar volumes and compressibilities of amino alcohols, with a focus on 3-amino-1-propanol, 2-amino-1-propanol, 3-amino-1,2-propanediol, and 1,3-diamino-2-propanol in water. The hydration numbers were calculated based on acoustic properties, and the impact of polar groups and the introduction of a second hydrophilic center on the properties studied was analyzed by comparing different amino alcohols.
JOURNAL OF CHEMICAL THERMODYNAMICS
(2021)
Article
Pharmacology & Pharmacy
Zezhi Lin, Zunting Pang, Ke Zhang, Zhengjie Qian, Zhenjing Liu, Jianjun Zhang, Yuan Gao, Yuanfeng Wei
Summary: In this study, it was found that the addition of surfactant sodium lauryl sulfate (SLS) can increase the dissolution of insoluble drugs, but it significantly decreases the dissolution of crystalline lurasidone hydrochloride (LH). The insoluble single-phase amorphous LH-SLS complex formed during dissolution in 0.1% SLS aqueous solution, leading to gel formation and suppression of LH dissolution. An innovative strategy was developed to mitigate the inhibiting effect of SLS on LH dissolution based on potential competitive interactions.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2022)
Article
Environmental Sciences
Yong-Hyun Kim, Kyuhong Lee
Summary: Experimental findings show that shampoo aerosols may be generated during use, with higher mass concentrations observed compared to water aerosols. The volatile organic compounds in shampoo aerosols could pose inhalation safety risks.
ENVIRONMENTAL RESEARCH
(2022)
Article
Dermatology
Simon G. Danby, Paul V. Andrew, Rosie N. Taylor, Linda J. Kay, John Chittock, Abigail Pinnock, Intisar Ulhaq, Anna Fasth, Karin Carlander, Tina Holm, Michael J. Cork
Summary: The study reveals that not all emollient creams are the same for eczema patients. The commonly prescribed paraffin-based emollient cream has no effect on the skin's barrier, while the urea-glycerol cream significantly improves the skin's barrier and provides protection. Different emollient creams have different effects on the skin, and only certain types have the ability to improve the skin's barrier and protect against irritants that trigger eczema.
CLINICAL AND EXPERIMENTAL DERMATOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Parayatum Dhruv Rao, Adimalapu Hima Sandeep, Manavalan Madhana Madhubala, Sekar Mahalaxmi
Summary: In terms of cell compatibility, there was no statistical difference between N-EDTA and MTAD. N-EDTA showed higher efficacy in biofilm disruption and bacterial killing compared to MTAD, while both materials showed similar performance in smear layer removal and sealer penetration depth.
CLINICAL ORAL INVESTIGATIONS
(2023)
Article
Medicine, Research & Experimental
Yiwang Guo, Changquan Calvin Sun
Summary: This study demonstrates the prevalence of the phenomena where anionic surfactant sodium lauryl sulfate (SLS) leads to drug precipitation. It affects the kinetics of precipitation and forms insoluble lauryl sulfate salts. The authors suggest that effective mitigation strategies should be implemented in drug development to alleviate its negative impact on drug dissolution.
MOLECULAR PHARMACEUTICS
(2022)
Article
Cell Biology
Mohammad Amin Keshvari, Alireza Afshar, Sajad Daneshi, Arezoo Khoradmehr, Mandana Baghban, Mahdi Muhaddesi, Pouya Behrouzi, Mohammad Reza Miri, Hossein Azari, Iraj Nabipour, Reza Shirazi, Mehdi Mahmudpour, Amin Tamadon
Summary: An automatic decellularization device was developed to perfuse and decellularize male rats' kidneys using SLES and SDS, comparing their efficacy in kidney decellularization and post-transplantation angiogenesis. SLES showed better preservation of extracellular matrix and was the preferred solvent for kidney decellularization.
CELL AND TISSUE RESEARCH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Hatice Kaya Ozden, Ayse Adin Selcuk
Summary: The study found that allergens in toothpastes do not appear to stimulate the formation of recurrent aphthous stomatitis (RAS), but further research in larger patient series employing more toothpaste ingredients for intraoral patch testing is suggested.
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY
(2021)
Article
Engineering, Biomedical
Asrin Emami, Tahereh Talaei-Khozani, Zahra Vojdani, Nehleh Zarei Fard
Summary: The study compared the quality of decellularized bone produced through different methods, finding that SLES and SDS 0.5% were more effective in preserving ultrastructure and ECM constituents, as well as significantly increasing cell viability.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
(2021)
Article
Materials Science, Multidisciplinary
Ji-Han Kwak, In-Gyeong Kim, Yong-Bum Park, Se-Eun Shin
Summary: This study investigated the effect of controlling SLS content on the properties of electrodeposited Fe-Ni alloy. The experimental results showed that under low pH conditions, the composition of the alloy was not significantly affected by different SLS content, and a uniform composition was observed.
Article
Pharmacology & Pharmacy
Priscila de Souza Furtado, Alana Agnes Silva Camargo de Oliveira, Pryscila Santiago Rodrigues, Anna Rita Santiago de Paula Goncalves, Anna Raphaella Autran Colaco, Sandro Pinheiro da Costa, Mariana Muniz da Paz, Paloma Wetler Meireles Carreiros Assumpcao, Luciana Pereira Rangel, Alice Simon, Flavia Almada do Carmo, Lucio Mendes Cabral, Plinio Cunha
Summary: This study developed and characterized RVX-loaded PLGA/SLS or DMAB nanoparticles, and evaluated their pharmacological and toxicological profiles. The nanoparticles showed high encapsulation efficiency and suitable yields, with rapid initial liberation and sustained release in different pH environments. Importantly, in vivo evaluations demonstrated a time-dependent antithrombotic effect of RVX-loaded SLS or DMAB nanoparticles surpassing the free form of RVX, with no hemolytic or cytotoxic effects observed at various concentrations. These findings suggest that RVX-loaded SLS or DMAB nanoparticles are promising innovative therapeutic alternatives for thromboembolic diseases.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
(2023)
Article
Energy & Fuels
Gang Wang, Enmao Wang, Qiming Huang, Jing Feng, Jun Li
Summary: The use of surfactants in coal seam water injection can enhance wetting effect but impede the seepage stage, leading to deterioration of the permeability coefficient. After the addition of surfactants, the permeability coefficient shows a rapid decrease first and then gradually stabilizes.
Article
Pharmacology & Pharmacy
Gang Jin, Hai Ngo, Jing-Hao Cui, Jie Wang, Chulhun Park, Beom-Jin Lee
Summary: This study investigated the role of micellization of sodium lauryl sulfate (SLS) in enhancing the dissolution rate of poorly water-soluble drugs in poloxamer 407 (POX)-based solid dispersions (POX-based SDs) using the anti-solvent method. The results showed that incorporating micellar SLS into SDs via the anti-solvent method could effectively improve the physical and chemical properties of SDs, reduce particle aggregation and recrystallization, and enhance the dissolution rate of poorly water-soluble drugs.
Article
Pharmacology & Pharmacy
Yiwang Guo, Changquan Calvin Sun
Summary: This study examined two formulation strategies to mitigate the negative effect of sodium lauryl sulfate (SLS) on the dissolution of p-aminobenzoic acid (PABA), which are increasing the microenvironment pH and reducing the critical micelle concentration (CMC) of SLS.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2022)
Article
Chemistry, Physical
Weixin Li, Liwei Zhu, Fenglun Zhang, Chunrui Han, Heng Xiang, Jianxin Jiang
Summary: The mixture of tea saponin and Sodium Lauryl Ether Sulfate (AES) exhibits synergistic effects, promoting foam stability and interfacial activity. Low concentrations of tea saponin reduce interfacial tension and improve foam stability. The mixture shows stable interfacial activity under various conditions.
SURFACES AND INTERFACES
(2022)
Article
Chemistry, Physical
Janak Adhikari, Ajaya Bhattarai, Narendra Kumar Chaudhary
Summary: This study aimed to design and develop surfactant-incorporated drugs with improved antibacterial properties and drug delivery systems. A Schiff base ligand and its two metal complexes were synthesized and fully characterized. The complexes showed remarkable antibacterial activities and their drug-like properties were predicted through in silico ADME study.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Multidisciplinary Sciences
Summi Rai, Ananda Kafle, Hari Prasad Devkota, Ajaya Bhattarai
Summary: The surface-active properties of saponins extracted from Jatropha curcas L. leaves and stem bark were investigated in this study. Conductivity and surface tension measurements showed that Jatropha curcas saponin exhibited micellar behavior, with the average CMC values of 0.50 g/L and 0.75 g/L for leaf and stem bark saponin, respectively. Stem bark saponin demonstrated better surface activity and potential detergency, reducing the surface tension of water to a greater extent (γCMC = 37.65 mN/m) compared to leaf saponin (γCMC = 49.27 mN/m). The results suggest that both leaf and stem bark saponins from Jatropha curcas can be environmentally friendly alternatives to synthetic surfactants.
Article
Multidisciplinary Sciences
Janak Adhikari, Ajaya Bhattarai, Narendra Kumar Chaudhary
Summary: This manuscript presents a dataset on various aspects including SEM-EDX analysis, surfactant properties, thermokinetics, and corrosion inhibition activity of complexes 1 and 2 with surfactant-based Schiff base ligand (HL). The dataset includes analyzed data related to thermokinetics, SEM micrographs and EDX images, as well as detailed analysis of critical micelle concentration and surfactant behavior of the synthesized complexes. It also provides data on the corrosion inhibition activity of all synthesized compounds. The dataset is relevant to the research article titled "Bioinorganic interest on Co(II) and Zn(II) complexes of pyrrole-based surfactant ligand: Synthesis, characterization, and in silico-ADME study."
Article
Multidisciplinary Sciences
Neelam Shahi, Sujit Kumar Shah, Amar Prasad Yadav, Ajaya Bhattarai
Summary: The interaction between methyl red and cetylpyridinium chloride in the methanol-water system was studied using a spectrophotometric technique. Parameters such as dye concentration, surfactant concentration, pH, absorbance, and solvent composition were investigated. The UV-Vis technique was used to measure the CMCs of cetylpyridinium chloride with methyl red, and spectral data were analyzed to determine various constants.
GAZI UNIVERSITY JOURNAL OF SCIENCE
(2023)
Article
Crystallography
Gunay Z. Mammadova, Selbi Annadurdyyeva, Gleb M. Burkin, Victor N. Khrustalev, Mehmet Akkurt, Sema Ozturk Yildirim, Ajaya Bhattarai
Summary: In the title compound, C-H···O hydrogen bonds link adjacent molecules in a three-dimensional network, while pi-pi stacking interactions result in chains parallel to the a axis. The Hirshfeld surface analysis indicates that O···H/H···O, H···H and C···H/H···C interactions are the most significant contributors to the crystal packing.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
(2023)
Article
Crystallography
Vusala A. Aliyeva, Fargana S. Aliyeva, Mehmet Akkurt, Sema Ozturk Yildirim, Ajaya Bhattarai
Summary: In the polymeric compound, Na+ cations are linked into a parallel chain by sharing water molecules. Each Na+ cation in the chain is bonded to a terminal water molecule and an SO3- group of the sulfonate anion. Hydrogen bonds and pi-pi interactions connect these chains into a three-dimensional network.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
(2023)
Article
Crystallography
Sema Ozturk Yildirim, Mehmet Akkurt, Anastasia A. Ershova, Mikhail S. Grigoriev, Bruno G. M. Rocha, Ajaya Bhattarai
Summary: The title compound is characterized by a main twelve-membered difuryl ring with dihedral angles of 76.14 (5) and 33.81 (5) degrees between the furan rings. The six-membered nitrogen heterocycle exhibits a twist-boat conformation. In the crystal, the molecules are connected by various intermolecular interactions, forming zigzag chains and sheets.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
(2023)
Article
Crystallography
Elvin G. Karimli, Victor N. Khrustalev, Margarita N. Kurasova, Mehmet Akkurt, Ali N. Khalilov, Ajaya Bhattarai, Ibrahim G. Mamedov
Summary: In the title compound, the cyclohexane rings exist in boat and half-chair conformations. Intermolecular C-H∙∙∙O hydrogen bonds connect adjacent molecules, forming a three-dimensional network in the crystal. The crystal packing is mainly determined by H∙∙∙H interactions, accounting for 63.0% according to a Hirshfeld surface study.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
(2023)
Article
Crystallography
Farid N. Naghiyev, Victor N. Khrustalev, Huseyn M. Mamedov, Mehmet Akkurt, Ali N. Khalilov, Ajaya Bhattarai, Ibrahim G. Mamedov
Summary: In the title compound, the [1,2,4]triazolo[1,5-a]pyridine ring system is planar and shows dihedral angles with the phenylamino and phenyl rings. The crystal structure is formed by intermolecular hydrogen bonds and π-π stacking interactions between pyridine rings, as well as by van der Waals interactions.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
(2023)
Article
Crystallography
Sema Ozturk Yildirim, Mehmet Akkurt, Gokalp Cetin, Rahime Simsek, Ray J. Butcher, Ajaya Bhattarai
Summary: In the title compound, the conformation of the 1,4-dihydropyridine ring is distorted boat, and the cyclohexene ring almost adopts a half-chair conformation. In the crystal, intermolecular N-H···O hydrogen bonds form chains with C(6) graph-set motif along the a-axis. These chains are connected by C-H···O and C-H···F interactions to form a three-dimensional network. Additionally, C-H···π interactions link the molecules into layers parallel to the (100) plane. A Hirshfeld surface analysis was conducted to investigate the intermolecular interactions further.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
(2023)
Article
Crystallography
Farid N. Naghiyev, Victor N. Khrustalev, Mehmet Akkurt, Ali N. Khalilov, Ajaya Bhattarai, Fuad Sh. Kerimli, Ibrahim G. Mamedov
Summary: The title compound contains two independent molecules in its asymmetric unit. One of the molecules exhibits rotational disorder in the thiophene ring, with two orientations that are not equivalent. In the crystal, the molecules are connected by intermolecular hydrogen bonds and van der Waals interactions to form ribbons along the a-axis.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
(2023)
Article
Chemistry, Applied
Summi Rai, Bishnu Shau Rauniyar, Ajaya Bhattarai
Summary: This study investigates the effect of surfactants on the wettability of aluminium foil by measuring the contact angle. As the volume fraction of isopropanol on aluminium foil increases, the contact angle increases and the surface free energy decreases. These findings are important for the application of surfactants to improve the wettability of aluminium foil.
TENSIDE SURFACTANTS DETERGENTS
(2023)
Article
Crystallography
Firudin I. Guseinov, Viacheslav O. Ovsyannikov, Pavel V. Sokolovskiy, Yurii L. Sebyakin, Aida I. Samigullina, Mehmet Akkurt, Sevim Turktekin Celikesi, Ajaya Bhattarai
Summary: This study reports the crystal structure of a new salt compound, presenting the detailed intermolecular interactions and layered structure.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
(2023)
Article
Crystallography
Gunay Z. Mammadova, Dmitriy F. Mertsalov, Dmitriy M. Shchevnikov, Mikhail S. Grigoriev, Mehmet Akkurt, Sema Ozturk Yildrim, Ajaya Bhattarai
Summary: This paper presents the crystal structures of three compounds and their interactions, revealing the molecular arrangement and bonding modes between them.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
(2023)
Article
Crystallography
Mehmet Akkurt, Farid N. Naghiyev, Victor N. Khrustalev, Khammed A. Asadov, Ali N. Khalilov, Ajaya Bhattarai, Ibrahim G. Mamedov
Summary: The crystal structure of a new compound is reported, where molecules are stabilized by intermolecular C-H···O, π-π stacking, and van der Waals interactions.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
(2023)
