Cerebral Neovascularization in Diabetes: Implications for Stroke Recovery and beyond

Vascular endothelial growth factors (VEGFs) and stroke

(2013) David A. Greenberg et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

VEGF Secreted by Hypoxic Muller Cells Induces MMP-2 Expression and Activity in Endothelial Cells to Promote Retinal Neovascularization in Proliferative Diabetic Retinopathy

(2013) M. Rodrigues et al.   DIABETES

Regulation of angiogenesis by PI3K signaling networks

(2013) Mariona Graupera et al.   EXPERIMENTAL CELL RESEARCH

Early Inhibition of MMP Activity in Ischemic Rat Brain Promotes Expression of Tight Junction Proteins and Angiogenesis During Recovery

(2013) Yi Yang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Inflammation and oxidative stress in angiogenesis and vascular disease

(2013) Young-Woong Kim et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Neovascularization in diabetes and its complications. Unraveling the angiogenic paradox

(2013) Paulo Zoé Costa et al.   LIFE SCIENCES

LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling

(2013) Xiaomeng Wang et al.   NATURE

Citalopram enhances neurovascular regeneration and sensorimotor functional recovery after ischemic stroke in mice

(2013) A.R. Espinera et al.   NEUROSCIENCE

Postischemic Revascularization: From Cellular and Molecular Mechanisms to Clinical Applications

(2013) Jean-Sébastien Silvestre et al.   PHYSIOLOGICAL REVIEWS

Cerebral Neovascularization and Remodeling Patterns in Two Different Models of Type 2 Diabetes

(2013) Roshini Prakash et al.   PLoS One

Vascularization Pattern After Ischemic Stroke is Different in Control Versus Diabetic Rats

(2013) Roshini Prakash et al.   STROKE

Vasculogenesis in Experimental Stroke After Human Cerebral Endothelial Cell Transplantation

(2013) Hiroto Ishikawa et al.   STROKE

VEGF and Notch in Tip and Stalk Cell Selection

(2013) R. Blanco et al.   Cold Spring Harbor Perspectives in Medicine

Ang-2 upregulation correlates with increased levels of MMP-9, VEGF, EPO and TGFβ1 in diabetic eyes undergoing vitrectomy

(2012) Sirpa Loukovaara et al.   ACTA OPHTHALMOLOGICA

The role of glia in retinal vascular disease

(2012) Nathan J Coorey et al.   Clinical and Experimental Optometry

Activation of pericytes

(2012) Cécile Fligny et al.   CURRENT OPINION IN RHEUMATOLOGY

Enhanced Cerebral but Not Peripheral Angiogenesis in the Goto-Kakizaki Model of Type 2 Diabetes Involves VEGF and Peroxynitrite Signaling

(2012) R. Prakash et al.   DIABETES

Role of simvastatin and/or antioxidant vitamins in therapeutic angiogenesis in experimental diabetic hindlimb ischemia: effects on capillary density, angiogenesis markers, and oxidative stress

(2012) Mona F. El-Azab et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expression

(2012) Marco Reis et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Heme activates TLR4-mediated inflammatory injury via MyD88/TRIF signaling pathway in intracerebral hemorrhage

(2012) Sen Lin et al.   Journal of Neuroinflammation

Pathological neoangiogenesis depends on oxidative stress regulation by ATM

(2012) Yuji Okuno et al.   NATURE MEDICINE

Combination treatment of stroke with sub-therapeutic doses of Simvastatin and human umbilical cord blood cells enhances vascular remodeling and improves functional outcome

(2012) X. Cui et al.   NEUROSCIENCE

Ipsilateral versus contralateral spontaneous post-stroke neuroplastic changes: Involvement of BDNF?

(2012) A. Madinier et al.   NEUROSCIENCE

Diabetic Retinopathy

(2012) David A. Antonetti et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Endothelium in Diabetic Nephropathy

(2012) Andrew Advani et al.   SEMINARS IN NEPHROLOGY

Angiogenesis

(2012) Adviye Ergul et al.   STROKE

Chronic Valproate Treatment Enhances Postischemic Angiogenesis and Promotes Functional Recovery in a Rat Model of Ischemic Stroke

(2012) Zhifei Wang et al.   STROKE

The Neurorestorative Benefit of GW3965 Treatment of Stroke in Mice

(2012) Xu Cui et al.   STROKE

Why is coronary collateral growth impaired in type II diabetes and the metabolic syndrome?

(2012) Petra Rocic   VASCULAR PHARMACOLOGY

Differential coronary resistance microvessel remodeling between type 1 and type 2 diabetic mice: Impact of exercise training

(2012) Aaron J. Trask et al.   VASCULAR PHARMACOLOGY

Slit2/Robo4 Signaling Modulates HIV-1 gp120-Induced Lymphatic Hyperpermeability

(2012) Xuefeng Zhang et al.   PLoS Pathogens

Macrophages in Collateral Arteriogenesis

(2012) Erik Fung et al.   Frontiers in Physiology

Cerebrovascular Complications of Diabetes: Focus on Stroke

(2012) Adviye Ergul et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Brain microvascular pericytes in health and disease

(2011) Turgay Dalkara et al.   ACTA NEUROPATHOLOGICA

Signal transduction by vascular endothelial growth factor receptors

(2011) Sina Koch et al.   BIOCHEMICAL JOURNAL

Basic and Therapeutic Aspects of Angiogenesis

(2011) Michael Potente et al.   CELL

Robo4-dependent Slit signaling stabilizes the vasculature during pathologic angiogenesis and cytokine storm

(2011) Nyall R London et al.   CURRENT OPINION IN HEMATOLOGY

Robo4 Maintains Vessel Integrity and Inhibits Angiogenesis by Interacting with UNC5B

(2011) Alexander W. Koch et al.   DEVELOPMENTAL CELL

Niaspan enhances vascular remodeling after stroke in type 1 diabetic rats

(2011) Xinchun Ye et al.   EXPERIMENTAL NEUROLOGY

Nervous vascular parallels: axon guidance and beyond

(2011) Marco Arese et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Tocotrienol Vitamin E Protects against Preclinical Canine Ischemic Stroke by Inducing Arteriogenesis

(2011) Cameron Rink et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Coronary collateral growth—Back to the future

(2011) William M. Chilian et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Molecular mechanisms and clinical applications of angiogenesis

(2011) Peter Carmeliet et al.   NATURE

Angiopoietin/Tie2 pathway mediates type 2 diabetes induced vascular damage after cerebral stroke

(2011) Xu Cui et al.   NEUROBIOLOGY OF DISEASE

The Neurovascular Link in Health and Disease: Molecular Mechanisms and Therapeutic Implications

(2011) Annelies Quaegebeur et al.   NEURON

Ups and Downs of Guided Vessel Sprouting: The Role of Polarity

(2011) Christina Y. Lee et al.   PHYSIOLOGY

Vascular Protection by Angiotensin Receptor Antagonism Involves Differential VEGF Expression in Both Hemispheres after Experimental Stroke

(2011) Weihua Guan et al.   PLoS One

Adverse Effects of Bone Marrow Stromal Cell Treatment of Stroke in Diabetic Rats

(2011) Jieli Chen et al.   STROKE

Longitudinal Magnetic Resonance Imaging of Sildenafil Treatment of Embolic Stroke in Aged Rats

(2011) Guangliang Ding et al.   STROKE

Granulocyte Colony-Stimulating Factor Enhances Arteriogenesis and Ameliorates Cerebral Damage in a Mouse Model of Ischemic Stroke

(2011) Yukio Sugiyama et al.   STROKE

The role of VEGF/VEGFR2 signaling in peripheral stimulation-induced cerebral neurovascular regeneration after ischemic stroke in mice

(2011) Wen-Lei Li et al.   EXPERIMENTAL BRAIN RESEARCH

Mechanisms of arteriogenesis

(2010) W. Cai et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Post-acute delivery of erythropoietin induces stroke recovery by promoting perilesional tissue remodelling and contralesional pyramidal tract plasticity

(2010) Raluca Reitmeir et al.   BRAIN

The Promise of Cell-Based Therapies for Diabetic Complications

(2010) Yagna P.R. Jarajapu et al.   CIRCULATION RESEARCH

Diabetic Retinopathy: Targeting Vasoregression

(2010) H.-P. Hammes et al.   DIABETES

Diabetes-induced peroxynitrite impairs the balance of pro-nerve growth factor and nerve growth factor, and causes neurovascular injury

(2010) T. K. Ali et al.   DIABETOLOGIA

Hippocampal neurovascular and hypothalamic–pituitary–adrenal axis alterations in spontaneously type 2 diabetic GK rats

(2010) Juan Beauquis et al.   EXPERIMENTAL NEUROLOGY

Hemoglobin and Iron Handling in Brain after Subarachnoid Hemorrhage and the Effect of Deferoxamine on Early Brain Injury

(2010) Jin-Yul Lee et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Vascular Protection in Diabetic Stroke: Role of Matrix Metalloprotease-Dependent Vascular Remodeling

(2010) Mostafa M Elgebaly et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

EPCs and pathological angiogenesis: When good cells go bad

(2010) Sergio Li Calzi et al.   MICROVASCULAR RESEARCH

HMGB1 induces human lung endothelial cell cytoskeletal rearrangement and barrier disruption

(2010) Rachel K. Wolfson et al.   MICROVASCULAR RESEARCH

Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting

(2010) Lars Jakobsson et al.   NATURE CELL BIOLOGY

AXIS

(2010) Wolf R. Schäbitz et al.   STROKE

Role of Iron in Brain Injury After Intraventricular Hemorrhage

(2010) Zhi Chen et al.   STROKE

Axon Guidance Molecules in Vascular Patterning

(2010) R. H. Adams et al.   Cold Spring Harbor Perspectives in Biology

Redox-Dependent Mechanisms in Coronary Collateral Growth: The “Redox Window” Hypothesis

(2009) June Yun et al.   ANTIOXIDANTS & REDOX SIGNALING

Endothelial-Mural Cell Signaling in Vascular Development and Angiogenesis

(2009) Konstantin Gaengel et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The anti-angiogenic isoforms of VEGF in health and disease

(2009) Yan Qiu et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The possible mechanism for impaired angiogenesis after transient focal ischemia in type 2 diabetic GK rats: Different expressions of angiostatin and vascular endothelial growth factor

(2009) Meijia Zhu et al.   BIOMEDICINE & PHARMACOTHERAPY

Abnormal Angiogenesis in Diabetic Nephropathy

(2009) T. Nakagawa et al.   DIABETES

Adaptive Cerebral Neovascularization in a Model of Type 2 Diabetes: Relevance to Focal Cerebral Ischemia

(2009) W. Li et al.   DIABETES

Niaspan Treatment Increases Tumor Necrosis Factor-α-Converting Enzyme and Promotes Arteriogenesis after Stroke

(2009) Jieli Chen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Early Intervention of Tyrosine Nitration Prevents Vaso-Obliteration and Neovascularization in Ischemic Retinopathy

(2009) M. A. Abdelsaid et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Early Atorvastatin Reduces Hemorrhage after Acute Cerebral Ischemia in Diabetic Rats

(2009) H. F. Elewa et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Slit2–Robo4 signalling promotes vascular stability by blocking Arf6 activity

(2009) Christopher A. Jones et al.   NATURE CELL BIOLOGY

Diabetic Retinopathy: Current Management and Experimental Therapeutic Targets

(2009) Tayyeba K Ali et al.   PHARMACOTHERAPY

Electrical Stimulation of the Cerebral Cortex Exerts Antiapoptotic, Angiogenic, and Anti-Inflammatory Effects in Ischemic Stroke Rats Through Phosphoinositide 3-Kinase/Akt Signaling Pathway

(2009) Tanefumi Baba et al.   STROKE

Hyperglycemia, diabetes and stroke: Focus on the cerebrovasculature

(2009) Adviye Ergul et al.   VASCULAR PHARMACOLOGY

Silencing of directional migration in roundabout4 knockdown endothelial cells

(2008) Sukhbir Kaur et al.   BMC CELL BIOLOGY

Age-dependent impairment of HIF-1α expression in diabetic mice: Correction with electroporation-facilitated gene therapy increases wound healing, angiogenesis, and circulating angiogenic cells

(2008) Lixin Liu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Magnetic Resonance Imaging Investigation of Axonal Remodeling and Angiogenesis after Embolic Stroke in Sildenafil-Treated Rats

(2008) Guangliang Ding et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Insights into mechanisms behind arteriogenesis: what does the future hold?

(2008) Melany C. van Oostrom et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability

(2008) Christopher A Jones et al.   NATURE MEDICINE

Simvastatin Increases Notch Signaling Activity and Promotes Arteriogenesis After Stroke

(2008) Alex Zacharek et al.   STROKE