Hypoxia-Inducible Factor 1 is Essential for Spontaneous Recovery from Traumatic Brain Injury and is a Key Mediator of Heat Acclimation Induced Neuroprotection

Hypoxia Inducible Factor-1: Its Potential Role In Cerebral Ischemia

(2012) Neetu Singh et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease

(2012) Azeb Tadesse Argaw et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis

(2012) Carmen Chak-Lui Wong et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Accelerated atherosclerosis in patients with SLE—mechanisms and management

(2012) Brian J. Skaggs et al.   Nature Reviews Rheumatology

Hypoxia-Inducible Factor-1α Contributes to Brain Edema after Stroke by Regulating Aquaporins and Glycerol Distribution in Brain

(2011) Tetsuhiro Higashida et al.   CURRENT NEUROVASCULAR RESEARCH

Hyperthermia conditioned astrocyte-cultured medium protects neurons from ischemic injury by the up-regulation of HIF-1 alpha and the increased anti-apoptotic ability

(2011) Fang Du et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Differential Effects of HIF-1 Inhibition by YC-1 on the Overall Outcome and Blood-Brain Barrier Damage in a Rat Model of Ischemic Stroke

(2011) Jingqi Yan et al.   PLoS One

Adipose Tissue-specific Inhibition of Hypoxia-inducible Factor 1α Induces Obesity and Glucose Intolerance by Impeding Energy Expenditure in Mice

(2010) Xinmei Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Preliminary study on the effect of trauma-induced secondary cellular hypoxia in brain injury

(2010) Ren-qiang Huang et al.   NEUROSCIENCE LETTERS

NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment

(2010) E. J. Moon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Persisting mild hypothermia suppresses hypoxia-inducible factor-1α protein synthesis and hypoxia-inducible factor-1-mediated gene expression

(2009) Tomoharu Tanaka et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

RETRACTED: Synapse loss regulated by matrix metalloproteinases in traumatic brain injury is associated with hypoxia inducible factor-1α expression

(2009) Jamie Y. Ding et al.   BRAIN RESEARCH

Heat Acclimation Provides Sustained Improvement in Functional Recovery and Attenuates Apoptosis after Traumatic Brain Injury

(2009) Gali Umschwief et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mouse closed head injury model induced by a weight-drop device

(2009) Michael A Flierl et al.   Nature Protocols

AQP4 gene deletion in mice does not alter blood–brain barrier integrity or brain morphology

(2009) S. Saadoun et al.   NEUROSCIENCE

Water transport between CNS compartments: contributions of aquaporins and cotransporters

(2009) N. MacAulay et al.   NEUROSCIENCE

Hypoxia-inducible factor-1α signaling in aquaporin upregulation after traumatic brain injury

(2009) Jamie Y. Ding et al.   NEUROSCIENCE LETTERS

Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization

(2009) K. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Analysis of Regional Microvascular Loss and Recovery following Two Grades of Fluid Percussion Trauma: A Role for Hypoxia-Inducible Factors in Traumatic Brain Injury

(2008) Eugene Park et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Intracerebral VEGF injection highly upregulates AQP4 mRNA and protein in the perivascular space and glia limitans externa

(2007) Inmaculada Rite et al.   NEUROCHEMISTRY INTERNATIONAL