CADASIL Mutations and shRNA Silencing of NOTCH3 Affect Actin Organization in Cultured Vascular Smooth Muscle Cells

Co-aggregate formation of CADASIL-mutant NOTCH3: a single-particle analysis

(2011) Marco Duering et al.   HUMAN MOLECULAR GENETICS

Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease

(2011) J. F. Arboleda-Velasquez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease

(2010) Anne Joutel et al.   JOURNAL OF CLINICAL INVESTIGATION

Congruence between NOTCH3 mutations and GOM in 131 CADASIL patients

(2009) Saara Tikka et al.   BRAIN

Distinct phenotypic and functional features of CADASIL mutations in the Notch3 ligand binding domain

(2009) Marie Monet-Leprêtre et al.   BRAIN

CADASIL mutations enhance spontaneous multimerization of NOTCH3

(2009) C. Opherk et al.   HUMAN MOLECULAR GENETICS

Mutations in NOTCH3 cause the formation and retention of aggregates in the endoplasmic reticulum, leading to impaired cell proliferation

(2009) Keikichi Takahashi et al.   HUMAN MOLECULAR GENETICS

Mechanisms that regulate adaptor binding to  -integrin cytoplasmic tails

(2009) K. R. Legate et al.   JOURNAL OF CELL SCIENCE

Notch3 Is a Major Regulator of Vascular Tone in Cerebral and Tail Resistance Arteries

(2008) E.J. Belin de Chantemèle et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Notch Signaling Regulates Platelet-Derived Growth Factor Receptor-β Expression in Vascular Smooth Muscle Cells

(2008) Shaobo Jin et al.   CIRCULATION RESEARCH

Role of platelet-derived growth factors in physiology and medicine

(2008) J. Andrae et al.   GENES & DEVELOPMENT

Enhanced L-arginine-induced vasoreactivity suggests endothelial dysfunction in CADASIL

(2008) N. Peters et al.   JOURNAL OF NEUROLOGY

Linking Notch signaling to ischemic stroke

(2008) J. F. Arboleda-Velasquez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA