Combination Therapy Targeting Akt and Mammalian Target of Rapamycin Improves Functional Outcome after Controlled Cortical Impact in Mice

Activation of the PI3K-Akt-mTOR signaling pathway promotes necrotic cell death via suppression of autophagy

(2014) You-Tong Wu et al.   Autophagy

AKT Inhibition Relieves Feedback Suppression of Receptor Tyrosine Kinase Expression and Activity

(2011) Sarat Chandarlapaty et al.   CANCER CELL

Aβ1–42 inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-3β

(2011) Jihoon Jo et al.   NATURE NEUROSCIENCE

Activation of autophagy and Akt/CREB signaling play an equivalent role in the neuroprotective effect of rapamycin in neonatal hypoxia-ischemia

(2010) Silvia Carloni et al.   Autophagy

Neuroprotective effect and cognitive outcome of chronic lithium on traumatic brain injury in mice

(2010) Zu-Fu Zhu et al.   BRAIN RESEARCH BULLETIN

Tumor Necrosis Factor Alpha and Fas Receptor Contribute to Cognitive Deficits Independent of Cell Death after Concussive Traumatic Brain Injury in Mice

(2010) Jugta Khuman et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The NCX3 Isoform of the Na+/Ca2+ Exchanger Contributes to Neuroprotection Elicited by Ischemic Postconditioning

(2010) Giuseppe Pignataro et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The intricate involvement of the Insulin-like growth factor receptor signaling in mild traumatic brain injury in mice

(2010) Vardit Rubovitch et al.   NEUROBIOLOGY OF DISEASE

ATP-mediated protein kinase B Akt/mammalian target of rapamycin mTOR/p70 ribosomal S6 protein p70S6 kinase signaling pathway activation promotes improvement of locomotor function after spinal cord injury in rats

(2010) L.Y. Hu et al.   NEUROSCIENCE

Activation of mammalian target of rapamycin signaling in spatial learning

(2010) Sihua Qi et al.   NEUROSCIENCE RESEARCH

Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis

(2008) Veronique Nogueira et al.   CANCER CELL

Akt-mediated phosphorylation of CDK2 regulates its dual role in cell cycle progression and apoptosis

(2008) S. Maddika et al.   JOURNAL OF CELL SCIENCE

The Role of Akt Signaling in Oxidative Stress Mediates NF-κB Activation in Mild Transient Focal Cerebral Ischemia

(2008) Yun Seon Song et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Necrostatin-1 Reduces Histopathology and Improves Functional Outcome after Controlled Cortical Impact in Mice

(2008) Zerong You et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Akt1 gene deletion and stroke

(2008) Jun Li et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Central Exercise Action Increases the AMPK and mTOR Response to Leptin

(2008) Eduardo R. Ropelle et al.   PLoS One

Immunosuppression after traumatic or ischemic CNS damage: It is neuroprotective and illuminates the role of microglial cells

(2007) Nils P. Hailer   PROGRESS IN NEUROBIOLOGY