The Contribution of L-Arginine to the Neurotoxicity of Recombinant Tissue Plasminogen Activator following Cerebral Ischemia: A Review of rtPA Neurotoxicity

Human Recombinant Tissue-Plasminogen Activator (Alteplase): Why Not Use the ‘Human’ Dose for Stroke Studies in Rats?

(2010) Benoît Haelewyn et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Low-Density Lipoprotein Receptor-Related Protein 1 Mediates Tissue-Type Plasminogen Activator-Induced Microglial Activation in the Ischemic Brain

(2009) Chen Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

A secretory phospholipase A2-mediated neuroprotection and anti-apoptosis

(2009) Arunmozhiarasi Armugam et al.   BMC NEUROSCIENCE

Dissociation and Protection of the Neurovascular Unit after Thrombolysis and Reperfusion in Ischemic Rat Brain

(2009) Toru Yamashita et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mechanistic Insight into Neurotoxicity of Tissue Plasminogen Activator-Induced Thrombolysis Products in a Rat Intraluminal Middle Cerebral Artery Occlusion Model

(2009) Fumiaki Oka et al.   JOURNAL OF NEUROTRAUMA

Stroke treatment with alteplase given 3·0–4·5 h after onset of acute ischaemic stroke (ECASS III): additional outcomes and subgroup analysis of a randomised controlled trial

(2009) Erich Bluhmki et al.   LANCET NEUROLOGY

Hemorrhagic profile of the fibrinolytic alfimeprase after ischemia and reperfusion

(2009) Aigang Lu et al.   NEUROLOGICAL RESEARCH

Albumin ameliorates tissue plasminogen activator-mediated blood–brain barrier permeability and ischemic brain injury in rats

(2009) Jin Tang et al.   NEUROLOGICAL RESEARCH

Minocycline and Tissue-Type Plasminogen Activator for Stroke

(2009) Livia S. Machado et al.   STROKE

The JNK Inhibitor XG-102 Protects from Ischemic Damage with Delayed Intravenous Administration Also in the Presence of Recombinant Tissue Plasminogen Activator

(2008) Karine Wiegler et al.   CEREBROVASCULAR DISEASES

The Functional Role of the Second NPXY Motif of the LRP1 β-Chain in Tissue-type Plasminogen Activator-mediated Activation ofN-Methyl-D-aspartate Receptors

(2008) Anne M. Martin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toward Safer Thrombolytic Agents in Stroke: Molecular Requirements for NMDA Receptor-Mediated Neurotoxicity

(2008) Jose P Lopez-Atalaya et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Activated Protein C Promotes Neovascularization and Neurogenesis in Postischemic Brain via Protease-Activated Receptor 1

(2008) M. Thiyagarajan et al.   JOURNAL OF NEUROSCIENCE

Inflammation and the neurovascular unit in the setting of focal cerebral ischemia

(2008) G.J. del Zoppo   NEUROSCIENCE

Key role of tissue plasminogen activator in neurovascular coupling

(2008) L. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Edaravone, a Free Radical Scavenger, Inhibits MMP-9–Related Brain Hemorrhage in Rats Treated With Tissue Plasminogen Activator

(2008) Kenji Yagi et al.   STROKE

Tissue-type plasminogen activator in the ischemic brain: more than a thrombolytic

(2008) Manuel Yepes et al.   TRENDS IN NEUROSCIENCES