Iturin A-like lipopeptides from Bacillus subtilis trigger apoptosis, paraptosis, and autophagy in Caco-2 cells

Potential of Bacillus subtilis lipopeptides in anti-cancer I: induction of apoptosis and paraptosis and inhibition of autophagy in K562 cells

(2018) Haobin Zhao et al.   AMB Express

Synthesis and Evaluation of New Pyrazoline Derivatives as Potential Anticancer Agents in HepG-2 Cell Line

(2017) Weijie Xu et al.   MOLECULES

Ten Years of Progress in Colon Cancer Therapy

(2017) Paul F. Engstrom   Journal of the National Comprehensive Cancer Network

Colon cancer targeting using conjugates biomaterial 5-flurouracil

(2016) Soleiman Jaferian et al.   BIOMEDICINE & PHARMACOTHERAPY

The MTT and Crystal Violet Assays

(2016) A. Almutary et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Erratum: Pioneering apoptosis-targeted cancer drug poised for FDA approval

(2016) Asher Mullard   NATURE REVIEWS DRUG DISCOVERY

Paraptosis in the anti-cancer arsenal of natural products

(2016) Dongjoo Lee et al.   PHARMACOLOGY & THERAPEUTICS

Modeling leucine's metabolic pathway and knockout prediction improving the production of surfactin, a biosurfactant fromBacillus subtilis

(2015) François Coutte et al.   Biotechnology Journal

Microbial amphiphiles: a class of promising new-generation anticancer agents

(2015) Goutam Dey et al.   DRUG DISCOVERY TODAY

MicroRNA-101 protects cardiac fibroblasts from hypoxia-induced apoptosis via inhibition of the TGF-β signaling pathway

(2015) Xin Zhao et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Mitochondrial Dysfunction and Ca2+Overload Contributes to Hesperidin Induced Paraptosis in Hepatoblastoma Cells, HepG2

(2015) Silvia Yumnam et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Lipopeptide surfactants: Production, recovery and pore forming capacity

(2015) Mnif Inès et al.   PEPTIDES

The oncolytic peptide LTX-315 kills cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization

(2015) Heng Zhou et al.   Oncotarget

Marine lipopeptide Iturin A inhibits Akt mediated GSK3β and FoxO3a signaling and triggers apoptosis in breast cancer

(2015) Goutam Dey et al.   Scientific Reports

Modeling leucine's metabolic pathway and knockout prediction improving the production of surfactin, a biosurfactant fromBacillus subtilis

(2015) François Coutte et al.   Biotechnology Journal

Targeting Tumor Suppressor p53 for Cancer Therapy: Strategies, Challenges and Opportunities

(2014) Bo Hong et al.   CURRENT DRUG TARGETS

Sheet-type titania, but not P25, induced paraptosis accompanying apoptosis in murine alveolar macrophage cells

(2014) Eun-Jung Park et al.   TOXICOLOGY LETTERS

Induction of apoptosis in human cancer cells by a Bacillus lipopeptide bacillomycin D

(2013) Sachin N. Hajare et al.   BIOCHIMIE

ApoG2 induces ER stress-dependent apoptosis in gastric cancer cells in vitro and its real-time evaluation by bioluminescence imaging in vivo

(2013) Jing Xin et al.   CANCER LETTERS

Involvement of PKA and HO-1 signaling in anti-inflammatory effects of surfactin in BV-2 microglial cells

(2013) Sun Young Park et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Reactive oxygen species involvement in apoptosis and mitochondrial damage in Caco-2 cells induced by enniatins A, A1, B and B1

(2013) A. Prosperini et al.   TOXICOLOGY LETTERS

Identification of surfactins and iturins produced by potent fungal antagonist, Bacillus subtilis K1 isolated from aerial roots of banyan (Ficus benghalensis) tree using mass spectrometry

(2013) Khyati V. Pathak et al.   3 Biotech

Regulation of the Intrinsic Apoptosis Pathway by Reactive Oxygen Species

(2012) Chu-Chiao Wu et al.   ANTIOXIDANTS & REDOX SIGNALING

Simultaneous mitochondrial Ca2+ overload and proteasomal inhibition are responsible for the induction of paraptosis in malignant breast cancer cells

(2012) Mi Jin Yoon et al.   CANCER LETTERS

Paraptosis accompanied by autophagy and apoptosis was induced by celastrol, a natural compound with influence on proteasome, ER stress and Hsp90

(2012) Wen-Bo Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Permeabilization of the Mitochondrial Outer Membrane by Bax/Truncated Bid (tBid) Proteins as Sensitized by Cardiolipin Hydroperoxide Translocation

(2011) Witold Korytowski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel copper complex induces paraptosis in colon cancer cells via the activation of ER stress signalling

(2011) Valentina Gandin et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Paraptosis-like cell death induced by yessotoxin

(2011) Mónica Suárez Korsnes et al.   TOXICOLOGY IN VITRO

Enhancement of imatinib-induced apoptosis of BCR/ABL-expressing cells by nutlin-3 through synergistic activation of the mitochondrial apoptotic pathway

(2010) Tetsuya Kurosu et al.   APOPTOSIS

Glucocorticoid induces mesenchymal-to-epithelial transition and inhibits TGF-β1-induced epithelial-to-mesenchymal transition and cell migration

(2010) Liang Zhang et al.   FEBS LETTERS

Surfactin Activity Depends on the Membrane Dipole Potential

(2010) Olga S. Ostroumova et al.   LANGMUIR

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Mitochondrial calcium and the permeability transition in cell death

(2009) John J. Lemasters et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Surfactin induces apoptosis in human breast cancer MCF-7 cells through a ROS/JNK-mediated mitochondrial/caspase pathway

(2009) Xiao-hong Cao et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Bcl-2 Inhibitors: Targeting Mitochondrial Apoptotic Pathways in Cancer Therapy

(2009) M. H. Kang et al.   CLINICAL CANCER RESEARCH

Superoxide anion and proteasomal dysfunction contribute to curcumin-induced paraptosis of malignant breast cancer cells

(2009) Mi Jin Yoon et al.   FREE RADICAL BIOLOGY AND MEDICINE

Taxol induces paraptosis independent of both protein synthesis and MAPK pathway

(2009) Qingrui Sun et al.   JOURNAL OF CELLULAR PHYSIOLOGY