Curcumin: A naturally occurring autophagy modulator

Curcumin: A natural modulator of immune cells in systemic lupus erythematosus

(2018) Amir Abbas Momtazi-Borojeni et al.   AUTOIMMUNITY REVIEWS

Autophagy in glioma cells: An identity crisis with a clinical perspective

(2018) I.V. Ulasov et al.   CANCER LETTERS

Role of autophagy in environmental neurotoxicity

(2018) C. Pellacani et al.   ENVIRONMENTAL POLLUTION

Curcumin regulates proliferation, autophagy, and apoptosis in gastric cancer cells by affecting PI3K and P53 signaling

(2018) Hongbing Fu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MicroRNA-7 facilitates the degradation of alpha-synuclein and its aggregates by promoting autophagy

(2018) Doo Chul Choi et al.   NEUROSCIENCE LETTERS

Curcumin suppresses the progression of laryngeal squamous cell carcinoma through the upregulation of miR-145 and inhibition of the PI3K/Akt/mTOR pathway

(2018) Xiaofeng Zhu et al.   OncoTargets and Therapy

Autophagy in the presynaptic compartment in health and disease

(2017) Vinoy Vijayan et al.   JOURNAL OF CELL BIOLOGY

Curcumin: A Naturally Occurring Modulator of Adipokines in Diabetes

(2017) Jafar Hajavi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Protective effects of curcumin against aflatoxicosis: A comprehensive review

(2017) Mohammad Mohajeri et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Curcumin, hemostasis, thrombosis, and coagulation

(2017) Faeze Keihanian et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Curcumin sensitizes prostate cancer cells to radiation partly via epigenetic activation of miR-143 and miR-143 mediated autophagy inhibition

(2017) Jianbo Liu et al.   JOURNAL OF DRUG TARGETING

Curcumin attenuates paraquat-induced cell death in human neuroblastoma cells through modulating oxidative stress and autophagy

(2017) Thiranut Jaroonwitchawan et al.   NEUROSCIENCE LETTERS

Curcumin induces apoptotic cell death and protective autophagy in human gastric cancer cells

(2017) Wei Li et al.   ONCOLOGY REPORTS

Effects of curcumin on HDL functionality

(2017) Shiva Ganjali et al.   PHARMACOLOGICAL RESEARCH

Tetrahydrocurcumin attenuates carbon tetrachloride-induced hepatic fibrogenesis by inhibiting the activation and autophagy of hepatic stellate cells

(2017) Mei-Ling Tsai et al.   Journal of Functional Foods

JNK pathway mediates curcumin-induced apoptosis and autophagy in osteosarcoma MG63 cells

(2017) Yaowu Zhang et al.   Experimental and Therapeutic Medicine

Curcumin induces apoptosis and protective autophagy in castration-resistant prostate cancer cells through iron chelation

(2017) Chunguang Yang et al.   Drug Design Development and Therapy

Curcumin blocks autophagy and activates apoptosis of malignant mesothelioma cell lines and increases the survival of mice intraperitoneally transplanted with a malignant mesothelioma cell line

(2017) Laura Masuelli et al.   Oncotarget

The regulation of autophagy in porcine blastocysts: Regulation of PARylation-mediated autophagy via mammalian target of rapamycin complex 1 (mTORC1) signaling

(2016) Hye Ran Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Plant phenols and autophagy

(2016) N. K. Zenkov et al.   BIOCHEMISTRY-MOSCOW

The nephroprotection exerted by curcumin in maleate-induced renal damage is associated with decreased mitochondrial fission and autophagy

(2016) Eduardo Molina-Jijón et al.   BIOFACTORS

Evaluation of the anti-inflammatory action of curcumin analog (DM1): Effect on iNOS and COX-2 gene expression and autophagy pathways

(2016) Niraldo Paulino et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Combination of Hydroxyl Acetylated Curcumin and Ultrasound Induces Macrophage Autophagy with Anti-Apoptotic and Anti-Lipid Aggregation Effects

(2016) Longbin Zheng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Curcumin: A new candidate for melanoma therapy?

(2016) Hamed Mirzaei et al.   INTERNATIONAL JOURNAL OF CANCER

Curcumin Lowers Serum Lipids and Uric Acid in Subjects With Nonalcoholic Fatty Liver Disease

(2016) Yunes Panahi et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Role of microRNAs on the Regulation of Mitochondrial Biogenesis and Insulin Signaling in Skeletal Muscle

(2016) Tanes I. Lima et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Tetrahydrocurcumin provides neuroprotection in rats after traumatic brain injury: autophagy and the PI3K/AKT pathways as a potential mechanism

(2016) Yongyue Gao et al.   JOURNAL OF SURGICAL RESEARCH

Curcumin activates autophagy and attenuates oxidative damage in EA.hy926 cells via the Akt/mTOR pathway

(2016) SHOUYU GUO et al.   Molecular Medicine Reports

Curcumin downregulates human tumor necrosis factor-α levels: A systematic review and meta-analysis ofrandomized controlled trials

(2016) Amirhossein Sahebkar et al.   PHARMACOLOGICAL RESEARCH

Treatment of Non-alcoholic Fatty Liver Disease with Curcumin: A Randomized Placebo-controlled Trial

(2016) Sepideh Rahmani et al.   PHYTOTHERAPY RESEARCH

Curcumin targets the TFEB-lysosome pathway for induction of autophagy

(2016) Jianbin Zhang et al.   Oncotarget

Inhibition of Autophagy Enhances Curcumin United light irradiation-induced Oxidative Stress and Tumor Growth Suppression in Human Melanoma Cells

(2016) Tianhui Niu et al.   Scientific Reports

Nicotinate-Curcumin Impedes Foam Cell Formation from THP-1 Cells through Restoring Autophagy Flux

(2016) Hong-Feng Gu et al.   PLoS One

Inhibition of PI3K signaling triggered apoptotic potential of curcumin which is hindered by Bcl-2 through activation of autophagy in MCF-7 cells

(2015) Yunus Akkoç et al.   BIOMEDICINE & PHARMACOTHERAPY

Antioxidant and anti-inflammatory effects of curcuminoid-piperine combination in subjects with metabolic syndrome: A randomized controlled trial and an updated meta-analysis

(2015) Yunes Panahi et al.   CLINICAL NUTRITION

microRNA-143 is associated with the survival of ALDH1+CD133+ osteosarcoma cells and the chemoresistance of osteosarcoma

(2015) Jiahui Zhou et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Curcumin accelerates reendothelialization and ameliorates intimal hyperplasia in balloon-injured rat carotid artery via the upregulation of endothelial cell autophagy

(2015) DONGDONG CHEN et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Optimized curcumin formulations for the treatment of Alzheimer's disease: A patent evaluation

(2015) Abolfazl Shakeri et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Curcumin inhibits autophagy and apoptosis in hypoxia/reoxygenation-induced myocytes

(2015) ZHOUQING HUANG et al.   Molecular Medicine Reports

Curcumin induces autophagy, inhibits proliferation and invasion by downregulating AKT/mTOR signaling pathway in human melanoma cells

(2015) GUANGMING ZHAO et al.   ONCOLOGY REPORTS

Curcumin Reactivates Silenced Tumor Suppressor Gene RARβ by Reducing DNA Methylation

(2015) Apei Jiang et al.   PHYTOTHERAPY RESEARCH

Autophagy: An emerging target for cancer therapy

(2014) Maria Høyer-Hansen et al.   Autophagy

Curcumin, a component of golden spice: From bedside to bench and back

(2014) Sahdeo Prasad et al.   BIOTECHNOLOGY ADVANCES

Downregulation of PI3K/Akt/mTOR signaling pathway in curcumin-induced autophagy in APP/PS1 double transgenic mice

(2014) Chen Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

miR-143 inhibits cell proliferation by targeting autophagy-related 2B in non-small cell lung cancer H1299 cells

(2014) JIALI WEI et al.   Molecular Medicine Reports

Novel curcumin analogue IHCH exhibits potent anti-proliferative effects by inducing autophagy in A549 lung cancer cells

(2014) GUANG-ZHOU ZHOU et al.   Molecular Medicine Reports

The Chemistry of Curcumin: From Extraction to Therapeutic Agent

(2014) Kavirayani Priyadarsini   MOLECULES

Dual effect of curcumin in preventing atherosclerosis: the potential role of pro-oxidant–antioxidant mechanisms

(2014) Amirhossein Sahebkar   NATURAL PRODUCT RESEARCH

Curcuminoids for the management of hypertriglyceridaemia

(2014) Amirhossein Sahebkar   Nature Reviews Cardiology

Natural autophagy regulators in cancer therapy: a review

(2014) Qian Ding et al.   PHYTOCHEMISTRY REVIEWS

Curcumin Combined with Oxaliplatin Effectively Suppress Colorectal Carcinomain vivoThrough Inducing Apoptosis

(2014) Li-da Guo et al.   PHYTOTHERAPY RESEARCH

Adjuvant Therapy with Bioavailability-Boosted Curcuminoids Suppresses Systemic Inflammation and Improves Quality of Life in Patients with Solid Tumors: A Randomized Double-Blind Placebo-Controlled Trial

(2014) Yunes Panahi et al.   PHYTOTHERAPY RESEARCH

Autophagy and Apoptosis in Hepatocellular Carcinoma Induced by EF25-(GSH)2: A Novel Curcumin Analog

(2014) Tao Zhou et al.   PLoS One

Degradation of mutant p53H175 protein by Zn(II) through autophagy

(2014) A Garufi et al.   Cell Death & Disease

Chaperone-mediated autophagy: roles in neurodegeneration

(2014) Gang Wang et al.   Translational Neurodegeneration

Regulation of HA14-1 mediated oxidative stress, toxic response, and autophagy by curcumin to enhance apoptotic activity in human embryonic kidney cells

(2013) Kishu Ranjan et al.   BIOFACTORS

SIRT1 Regulates the Human Alveolar Epithelial A549 Cell Apoptosis Induced byPseudomonas AeruginosaLipopolysaccharide

(2013) Xiaoli Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

B19, a Novel Monocarbonyl Analogue of Curcumin, Induces Human Ovarian Cancer Cell Apoptosis via Activation of Endoplasmic Reticulum Stress and the Autophagy Signaling Pathway

(2013) Wanglei Qu et al.   International Journal of Biological Sciences

Development and evaluation of a novel phytosome-loaded chitosan microsphere system for curcumin delivery

(2013) Jifen Zhang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Curcumin Induces Autophagy via Activating the AMPK Signaling Pathway in Lung Adenocarcinoma Cells

(2013) Kui Xiao et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

The possible roles of vitamin D and curcumin in treating gonorrhea

(2013) Dima A. Youssef et al.   MEDICAL HYPOTHESES

miR128 up-regulation correlates with impaired amyloid β(1-42) degradation in monocytes from patients with sporadic Alzheimer's disease

(2013) Roberto Tiribuzi et al.   NEUROBIOLOGY OF AGING

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

A synthetic curcumin derivative hydrazinobenzoylcurcumin induces autophagy in A549 lung cancer cells

(2013) Guang-Zhou Zhou et al.   PHARMACEUTICAL BIOLOGY

bis-Dehydroxy-Curcumin Triggers Mitochondrial-Associated Cell Death in Human Colon Cancer Cells through ER-Stress Induced Autophagy

(2013) Valentina Basile et al.   PLoS One

Autophagy and mitophagy in cellular damage control

(2013) Jianhua Zhang   Redox Biology

Curcumin-induced autophagy contributes to the decreased survival of oral cancer cells

(2012) Ji Young Kim et al.   ARCHIVES OF ORAL BIOLOGY

Curcumin induces autophagy to protect vascular endothelial cell survival from oxidative stress damage

(2012) Jing Han et al.   Autophagy

miRNA-130a Targets ATG2B and DICER1 to Inhibit Autophagy and Trigger Killing of Chronic Lymphocytic Leukemia Cells

(2012) V. Kovaleva et al.   CANCER RESEARCH

Plant natural compounds: targeting pathways of autophagy as anti-cancer therapeutic agents

(2012) X. Zhang et al.   CELL PROLIFERATION

Tetrahydrocurcumin Ameliorates Homocysteinylated Cytochrome-c Mediated Autophagy in Hyperhomocysteinemia Mice after Cerebral Ischemia

(2012) Neetu Tyagi et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Curcumin induces permanent growth arrest of human colon cancer cells: Link between senescence and autophagy

(2012) Grazyna Mosieniak et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Curcumin Induces Autophagy in ACC-MESO-1 Cells

(2012) Yoshikane Yamauchi et al.   PHYTOTHERAPY RESEARCH

Alpha-synuclein: from secretion to dysfunction and death

(2012) O Marques et al.   Cell Death & Disease

Chemo-resistant melanoma sensitized by tamoxifen to low dose curcumin treatment through induction of apoptosis and autophagy

(2011) Sudipa June Chatterjee et al.   CANCER BIOLOGY & THERAPY

Curcumin promotes differentiation of glioma-initiating cells by inducing autophagy

(2011) Wenzhuo Zhuang et al.   CANCER SCIENCE

Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL

Involvement of ROS in Curcumin-induced Autophagic Cell Death

(2011) Youn Ju Lee et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Tetrahydrocurcumin, a major metabolite of curcumin, induced autophagic cell death through coordinative modulation of PI3K/Akt-mTOR and MAPK signaling pathways in human leukemia HL-60 cells

(2011) Jia-Ching Wu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

CLEFMA—An anti-proliferative curcuminoid from structure–activity relationship studies on 3,5-bis(benzylidene)-4-piperidones

(2010) Pallavi Lagisetty et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Autophagy: cellular and molecular mechanisms

(2010) Danielle Glick et al.   JOURNAL OF PATHOLOGY

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Role of apoptosis in cardiovascular disease

(2009) Youngil Lee et al.   APOPTOSIS

Curcumin induces apoptosis-independent death in oesophageal cancer cells

(2009) G O'Sullivan-Coyne et al.   BRITISH JOURNAL OF CANCER

Autophagic and apoptotic mechanisms of curcumin-induced death in K562 cells

(2009) Yan-Li Jia et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Cancer chemopreventive activity of diversin from Ferula diversivittata in vitro and in vivo

(2009) M. Iranshahi et al.   PHYTOMEDICINE

Regulation of Autophagy by Reactive Oxygen Species (ROS): Implications for Cancer Progression and Treatment

(2008) Meghan B. Azad et al.   ANTIOXIDANTS & REDOX SIGNALING

Diet, Autophagy, and Cancer: A Review

(2008) K. Singletary et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases

(2008) Bharat B. Aggarwal et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Betulinic Acid for Cancer Treatment and Prevention

(2008) Simone Fulda   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Curcumin as “Curecumin”: From kitchen to clinic

(2007) Ajay Goel et al.   BIOCHEMICAL PHARMACOLOGY