Journal
JOURNAL OF CELLULAR PHYSIOLOGY
Volume 234, Issue 2, Pages 1237-1247Publisher
WILEY
DOI: 10.1002/jcp.27137
Keywords
prostate cancer; Wnt antagonists; Wnt signaling
Categories
Funding
- Iran National Science Foundation [96006612]
- Mashhad University of Medical Sciences [951860]
Ask authors/readers for more resources
Prostate cancer is a major cause of cancer-related death in males. Wnt/beta-catenin signaling plays a critical role in the pathogenesis of this disease by regulating angiogenesis, drug resistance, cell proliferation, and apoptosis. Suppression of Wnt canonical or noncanonical signaling pathways via Wnt biological or pharmacological antagonists is a potentially novel therapeutic approach for patients with prostate cancer. This review summarizes the role of Wnt signaling inhibitors in the pathogenesis of prostate cancer for a better understanding and hence a better management of this disease.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available