IGF-1 Alleviates NMDA-Induced Excitotoxicity in Cultured Hippocampal Neurons Against Autophagy via the NR2B/PI3K-AKT-mTOR Pathway

Chronic resistance training activates autophagy and reduces apoptosis of muscle cells by modulating IGF-1 and its receptors, Akt/mTOR and Akt/FOXO3a signaling in aged rats

(2013) Li Luo et al.   EXPERIMENTAL GERONTOLOGY

Autophagy in blood cancers: biological role and therapeutic implications

(2013) A. Nencioni et al.   HAEMATOLOGICA

Regulation of cardiac autophagy by insulin-like growth factor 1

(2013) Rodrigo Troncoso et al.   IUBMB LIFE

Tat-Collapsin Response Mediator Protein 2 (CRMP2) Increases the Survival of Neurons After NMDA Excitotoxity by Reducing the Cleavage of CRMP2

(2013) Yanling Yin et al.   NEUROCHEMICAL RESEARCH

The Neuroprotective Effects of Intramuscular Insulin-Like Growth Factor-I Treatment in Brain Ischemic Rats

(2013) Heng-Chih Chang et al.   PLoS One

Neuroprotective effect of estrogen: Role of nonsynaptic NR2B-containing NMDA receptors

(2012) Shui-bing Liu et al.   BRAIN RESEARCH BULLETIN

Excessive Autophagy Contributes to Neuron Death in Cerebral Ischemia

(2012) Ruoyang Shi et al.   CNS Neuroscience & Therapeutics

Neuronal Stimulation Induces Autophagy in Hippocampal Neurons That Is Involved in AMPA Receptor Degradation after Chemical Long-Term Depression

(2012) M. Shehata et al.   JOURNAL OF NEUROSCIENCE

Hydrogen peroxide attenuates the prosurvival signaling of insulin-like growth factor-1 through two pathways

(2012) Chengming Sun et al.   NEUROREPORT

The Reactivity, Distribution and Abundance of Non-Astrocytic Inner Retinal Glial (NIRG) Cells Are Regulated by Microglia, Acute Damage, and IGF1

(2012) Christopher P. Zelinka et al.   PLoS One

Inhibition of Autophagy Contributes to Ischemic Postconditioning-Induced Neuroprotection against Focal Cerebral Ischemia in Rats

(2012) Li Gao et al.   PLoS One

Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy

(2011) Rodrigo Troncoso et al.   CARDIOVASCULAR RESEARCH

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

IRS-2 Deficiency Impairs NMDA Receptor-Dependent Long-term Potentiation

(2011) Eduardo D. Martín et al.   CEREBRAL CORTEX

Stroke intervention pathways: NMDA receptors and beyond

(2011) Ted Weita Lai et al.   TRENDS IN MOLECULAR MEDICINE

Acute NMDA toxicity in cultured rat cerebellar granule neurons is accompanied by autophagy induction and late onset autophagic cell death phenotype

(2010) Shankar Sadasivan et al.   BMC NEUROSCIENCE

Insulin-Like Growth Factor I Enhances the Expression of Aromatase P450 by Inhibiting Autophagy

(2010) Bo Zhang et al.   ENDOCRINOLOGY

Estradiol potentiation of NR2B-dependent EPSCs is not due to changes in NR2B protein expression or phosphorylation

(2010) Melissa A. Snyder et al.   HIPPOCAMPUS

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Long-Term IGF-I Exposure Decreases Autophagy and Cell Viability

(2010) Alessandro Bitto et al.   PLoS One

Autophagy, a guardian against neurodegeneration

(2010) Moisés García-Arencibia et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Roles of zinc and metallothionein-3 in oxidative stress-induced lysosomal dysfunction, cell death, and autophagy in neurons and astrocytes

(2010) Sook-Jeong Lee et al.   Molecular Brain

The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases

(2009) Zhenyu Yue et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Neuroprotective Effects of IGF-I Following Kainic Acid-Induced Hippocampal Degeneration in the Rat

(2009) Panagiota Miltiadous et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Growth Factor-Dependent Trafficking of Cerebellar NMDA Receptors via Protein Kinase B/Akt Phosphorylation of NR2C

(2009) Bo-Shiun Chen et al.   NEURON

Pharmacological Strategies for Neuroprotection in Traumatic Brain Injury

(2008) J. Jennings et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY