Suppression of interactions between prostate tumor cell-surface integrin and endothelial ICAM-1 by simvastatin inhibits micrometastasis

Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins

(2015) Paula Vainio et al.   Oncotarget

Simultaneous modulation of the intrinsic and extrinsic pathways by simvastatin in mediating prostate cancer cell apoptosis

(2012) Anna Goc et al.   BMC CANCER

The differential effects of statins on the metastatic behaviour of prostate cancer

(2012) M Brown et al.   BRITISH JOURNAL OF CANCER

Akt1 mediates prostate cancer cell microinvasion and chemotaxis to metastatic stimuli via integrin β3 affinity modulation

(2012) A Goc et al.   BRITISH JOURNAL OF CANCER

Statin Use and Reduced Cancer-Related Mortality

(2012) Sune F. Nielsen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antiangiogenic Therapy for Cancer: An Update

(2012) Belal Al-Husein et al.   PHARMACOTHERAPY

Rac1 Activation Driven by 14-3-3ζ Dimerization Promotes Prostate Cancer Cell-Matrix Interactions, Motility and Transendothelial Migration

(2012) Anna Goc et al.   PLoS One

Phospho-Akt Immunoreactivity in Prostate Cancer: Relationship to Disease Severity and Outcome, Ki67 and Phosphorylated EGFR Expression

(2012) Peter Hammarsten et al.   PLoS One

Statins and prostate cancer: Molecular and clinical aspects

(2011) Georgios Papadopoulos et al.   EUROPEAN JOURNAL OF CANCER

Atorvastatin reduces vascular endothelial growth factor (VEGF) expression in human non-small cell lung carcinomas (NSCLCs) via inhibition of reactive oxygen species (ROS) production

(2011) Jie Chen et al.   Molecular Oncology

Normalization of the Vasculature for Treatment of Cancer and Other Diseases

(2011) Shom Goel et al.   PHYSIOLOGICAL REVIEWS

Statin medication use and the risk of biochemical recurrence after radical prostatectomy

(2010) Robert J. Hamilton et al.   CANCER

Differential Roles for Endothelial ICAM-1, ICAM-2, and VCAM-1 in Shear-Resistant T Cell Arrest, Polarization, and Directed Crawling on Blood-Brain Barrier Endothelium

(2010) O. Steiner et al.   JOURNAL OF IMMUNOLOGY

Anticancer Efficacy of Simvastatin on Prostate Cancer Cells and Tumor Xenografts Is Associated with Inhibition of Akt and Reduced Prostate-Specific Antigen Expression

(2010) S. T. Kochuparambil et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Statins inhibit the growth of variant human embryonic stem cells and cancer cellsin vitrobut not normal human embryonic stem cells

(2009) K Gauthaman et al.   BRITISH JOURNAL OF PHARMACOLOGY

Human antibodies targeting cell surface antigens overexpressed by the hormone refractory metastatic prostate cancer cells: ICAM-1 is a tumor antigen that mediates prostate cancer cell invasion

(2009) Fraser Conrad et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Akt1 is necessary for the vascular maturation and angiogenesis during cutaneous wound healing

(2008) Payaningal R. Somanath et al.   ANGIOGENESIS