The role of COX-2/PGE2 in gossypol-induced apoptosis of colorectal carcinoma cells

Chemoprevention in experimental animals

(2011) Nalini Namasivayam   Annals of the New York Academy of Sciences

Gossypol decreases tumor necrosis factor-α-induced intercellular adhesion molecule-1 expression via suppression of NF-κB activity

(2011) Dong-Oh Moon et al.   FOOD AND CHEMICAL TOXICOLOGY

(-)-Gossypol Suppresses the Growth of Human Prostate Cancer Xenografts via Modulating VEGF Signaling-Mediated Angiogenesis

(2011) X. Pang et al.   MOLECULAR CANCER THERAPEUTICS

The Prostaglandin E 2 Receptor EP4 Is Expressed by Human Platelets and Potently Inhibits Platelet Aggregation and Thrombus Formation

(2010) Sonia Philipose et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Risk of colorectal cancer in self-reported inflammatory bowel disease and modification of risk by statin and NSAID use

(2010) N. Jewel Samadder et al.   CANCER

Gossypol Induces Death Receptor-5 through Activation of the ROS-ERK-CHOP Pathway and Sensitizes Colon Cancer Cells to TRAIL

(2010) Bokyung Sung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

12-O-tetradecanoylphorbol-13-acetate-induced invasion/migration of glioblastoma cells through activating PKCα/ERK/NF-κB-dependent MMP-9 expression

(2010) Cheng-Wei Lin et al.   JOURNAL OF CELLULAR PHYSIOLOGY

c-Jun N-terminal kinase is largely involved in the regulation of tricellular tight junctions via tricellulin in human pancreatic duct epithelial cells

(2010) Takashi Kojima et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The Pan-Bcl-2 Inhibitor (-)-Gossypol Triggers Autophagic Cell Death in Malignant Glioma

(2010) V. Voss et al.   MOLECULAR CANCER RESEARCH

The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment

(2009) A. Greenhough et al.   CARCINOGENESIS

Different forms of cell death induced by putative BCL2 inhibitors

(2009) M Vogler et al.   CELL DEATH AND DIFFERENTIATION

Bcl-2 Inhibitors: Targeting Mitochondrial Apoptotic Pathways in Cancer Therapy

(2009) M. H. Kang et al.   CLINICAL CANCER RESEARCH

Prostaglandin E2 upregulates survivin expression via the EP1 receptor in hepatocellular carcinoma cells

(2009) Xiao-Ming Bai et al.   LIFE SCIENCES

The role of COX-2 in intestinal inflammation and colorectal cancer

(2009) D Wang et al.   ONCOGENE

Cyclooxygenase-2 Inhibition Prevents Migration of Colorectal Cancer Cells to Extracellular Matrix by Down-Regulation of Matrix Metalloproteinase-2 Expression

(2008) Edmund Leung et al.   DISEASES OF THE COLON & RECTUM

Combination of atorvastatin and celecoxib synergistically induces cell cycle arrest and apoptosis in colon cancer cells

(2008) Hang Xiao et al.   INTERNATIONAL JOURNAL OF CANCER