Knockdown of USP28 enhances the radiosensitivity of esophageal cancer cells via the c-Myc/hypoxia-inducible factor-1 alpha pathway

Simvastatin inhibits the development of radioresistant esophageal cancer cells by increasing the radiosensitivity and reversing EMT process via the PTEN-PI3K/AKT pathway

(2018) Yingying Jin et al.   EXPERIMENTAL CELL RESEARCH

miR-26a and miR-26b inhibit esophageal squamous cancer cell proliferation through suppression of c-MYC pathway

(2017) Juan Li et al.   GENE

Deubiquitinating enzyme USP22 positively regulates c-Myc stability and tumorigenic activity in mammalian and breast cancer cells

(2017) Dongyeon Kim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Brusatol-Mediated Inhibition of c-Myc Increases HIF-1α Degradation and Causes Cell Death in Colorectal Cancer under Hypoxia

(2017) Eun-Taex Oh et al.   Theranostics

ATM/ATR‐mediated phosphorylation of PALB2 promotes RAD51 function

(2016) Johanna K Ahlskog et al.   EMBO REPORTS

c-Myc Sustains Transformed Phenotype and Promotes Radioresistance of Embryonal Rhabdomyosarcoma Cell Lines

(2016) G. L. Gravina et al.   RADIATION RESEARCH

Microbiome and potential targets for chemoprevention of esophageal adenocarcinoma

(2016) Antonio Galvao Neto et al.   SEMINARS IN ONCOLOGY

Proteomics discovery of radioresistant cancer biomarkers for radiotherapy

(2015) Lei Chang et al.   CANCER LETTERS

Usp28 Counteracts Fbw7 in Intestinal Homeostasis and Cancer

(2015) M. E. Diefenbacher et al.   CANCER RESEARCH

Ubiquitin-specific protease 28 is overexpressed in human glioblastomas and contributes to glioma tumorigenicity by regulating MYC expression

(2015) Zengwu Wang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Overexpression of deubiquitinating enzyme USP28 promoted non-small cell lung cancer growth

(2015) Lei Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The involvement of c-Myc in the DNA double-strand break repair via regulating radiation-induced phosphorylation of ATM and DNA-PKcs activity

(2015) Fengmei Cui et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

USP1 targeting impedes GBM growth by inhibiting stem cell maintenance and radioresistance

(2015) Jin-Ku Lee et al.   NEURO-ONCOLOGY

HIF-1 Alpha Regulates the Response of Primary Sarcomas to Radiation Therapy through a Cell Autonomous Mechanism

(2015) Minsi Zhang et al.   RADIATION RESEARCH

The role of hypoxia-inducible factor-1α in radiation-induced autophagic cell death in breast cancer cells

(2015) Rui Zhong et al.   TUMOR BIOLOGY

Inhibition of DNA-PKcs enhances radiosensitivity and increases the levels of ATM and ATR in NSCLC cells exposed to carbon ion irradiation

(2015) LINA YANG et al.   Oncology Letters

Deubiquitinase USP9x Confers Radioresistance through Stabilization of Mcl-1

(2015) Donatella Trivigno et al.   NEOPLASIA

FDG-PET/CT during concomitant chemo radiotherapy for esophageal cancer: Reducing target volumes to deliver higher radiotherapy doses

(2014) Lamyaa Nkhali et al.   ACTA ONCOLOGICA

The deubiquitinase USP28 controls intestinal homeostasis and promotes colorectal cancer

(2014) Markus E. Diefenbacher et al.   JOURNAL OF CLINICAL INVESTIGATION

Ubiquitination in disease pathogenesis and treatment

(2014) Doris Popovic et al.   NATURE MEDICINE

Dual Regulation of Fbw7 Function and Oncogenic Transformation by Usp28

(2014) Christina Schülein-Völk et al.   Cell Reports

USP28 is a potential prognostic marker for bladder cancer

(2013) Guiying Guo et al.   TUMOR BIOLOGY

DNA Damage Sensing by the ATM and ATR Kinases

(2013) A. Marechal et al.   Cold Spring Harbor Perspectives in Biology

The Deubiquitinase USP28 Stabilizes LSD1 and Confers Stem-Cell-like Traits to Breast Cancer Cells

(2013) Yadi Wu et al.   Cell Reports

c-Myc enhances colon cancer cell-mediated angiogenesis through the regulation of HIF-1α

(2012) Cheng Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MYC Regulation of CHK1 and CHK2 Promotes Radioresistance in a Stem Cell-like Population of Nasopharyngeal Carcinoma Cells

(2012) W.-J. Wang et al.   CANCER RESEARCH

SirT1 Confers Hypoxia-induced Radioresistance via the Modulation of c-Myc Stabilization on Hepatoma Cells

(2012) Yuexia XIE et al.   JOURNAL OF RADIATION RESEARCH

Multimodal treatment of esophageal cancer

(2012) Florian Lordick et al.   LANGENBECKS ARCHIVES OF SURGERY

Balancing act: deubiquitinating enzymes in the nervous system

(2011) Sokol V. Todi et al.   TRENDS IN NEUROSCIENCES