Loss of Cbl-PI3K Interaction Enhances Osteoclast Survival due to p21-Ras Mediated PI3K Activation Independent of Cbl-b

E3 ubiquitin ligase-mediated regulation of bone formation and tumorigenesis

(2013) N Sévère et al.   Cell Death & Disease

Class IA phosphatidylinositol 3-kinase regulates osteoclastic bone resorption through protein kinase B-mediated vesicle transport

(2012) Masahiro Shinohara et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Abrogation of Cbl–PI3K Interaction Increases Bone Formation and Osteoblast Proliferation

(2011) Tracy Brennan et al.   CALCIFIED TISSUE INTERNATIONAL

Cbl-phosphatidylinositol 3 kinase interaction differentially regulates macrophage colony-stimulating factor-mediated osteoclast survival and cytoskeletal reorganization

(2010) Naga Suresh Adapala et al.   Annals of the New York Academy of Sciences

The Loss of Cbl-Phosphatidylinositol 3-Kinase Interaction Perturbs RANKL-mediated Signaling, Inhibiting Bone Resorption and Promoting Osteoclast Survival

(2010) Naga Suresh Adapala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TREM2- and DAP12-Dependent Activation of PI3K Requires DAP10 and Is Inhibited by SHIP1

(2010) Q. Peng et al.   Science Signaling

Loss of Cbl-b Increases Osteoclast Bone-Resorbing Activity and Induces Osteopenia

(2009) Arata Nakajima et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Pathway crosstalk between Ras/Raf and PI3K in promotion of M‐CSF‐induced MEK/ERK‐mediated osteoclast survival

(2008) Elizabeth W. Bradley et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The p85  Subunit of Class IA Phosphatidylinositol 3-Kinase Regulates the Expression of Multiple Genes Involved in Osteoclast Maturation and Migration

(2008) V. Munugalavadla et al.   MOLECULAR AND CELLULAR BIOLOGY