Increased interaction between PACT molecules in response to stress signals is required for PKR activation

Stress-Induced Phosphorylation of PACT Reduces Its Interaction with TRBP and Leads to PKR Activation

(2011) Madhurima Singh et al.   BIOCHEMISTRY

The PPAR-γ agonist troglitazone antagonizes survival pathways induced by STAT-3 in recombinant interferon-β treated pancreatic cancer cells

(2011) Giovanni Vitale et al.   BIOTECHNOLOGY ADVANCES

Effects of Interferons α/β on the Proliferation of Human Micro- and Macrovascular Endothelial Cells

(2011) Joris Erdmann et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Interactions between the double-stranded RNA-binding proteins TRBP and PACT define the Medipal domain that mediates protein-protein interactions

(2011) Ghislaine Laraki et al.   RNA Biology

Analysis of Monomeric and Dimeric Phosphorylated Forms of Protein Kinase R

(2010) Eric Anderson et al.   BIOCHEMISTRY

Biochemical Analysis of PKR Activation by PACT

(2009) Gregory A. Peters et al.   BIOCHEMISTRY

Characterization of the TRBP domain required for Dicer interaction and function in RNA interference

(2009) Sylvanne M Daniels et al.   BMC MOLECULAR BIOLOGY

Phosphorylation of the Human MicroRNA-Generating Complex Mediates MAPK/Erk Signaling

(2009) Zain Paroo et al.   CELL

Emerging Strategies to Strengthen the Anti-Tumour Activity of Type I Interferons: Overcoming Survival Pathways

(2009) M. Caraglia et al.   CURRENT CANCER DRUG TARGETS

RNA Dimerization Promotes PKR Dimerization and Activation

(2009) Laurie A. Heinicke et al.   JOURNAL OF MOLECULAR BIOLOGY

Mechanism of PKR Activation by dsRNA

(2008) Peter A. Lemaire et al.   JOURNAL OF MOLECULAR BIOLOGY

Essential Role of PACT-Mediated PKR Activation in Tunicamycin-Induced Apoptosis

(2008) Madhurima Singh et al.   JOURNAL OF MOLECULAR BIOLOGY

TRBP Control of PACT-Induced Phosphorylation of Protein Kinase R Is Reversed by Stress

(2008) A. Daher et al.   MOLECULAR AND CELLULAR BIOLOGY