Downregulation of PKD1 by shRNA results in defective osteogenic differentiation via cAMP/PKA pathway in human MG-63 cells

Conditional deletion of Pkd1 in osteocytes disrupts skeletal mechanosensing in mice

(2011) Zhousheng Xiao et al.   FASEB JOURNAL

Interaction of human serum albumin with 10-hydroxycamptothecin: spectroscopic and molecular modeling studies

(2011) Hui-Hui Sun et al.   MOLECULAR BIOLOGY REPORTS

Do cilia put brakes on the cell cycle?

(2011) Peter K. Jackson   NATURE CELL BIOLOGY

Role of the polycytin-primary cilia complex in bone development and mechanosensing

(2010) Z.S. Xiao et al.   Annals of the New York Academy of Sciences

Cyclic AMP-mediated cyst expansion

(2010) Darren P. Wallace   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells

(2010) Ronald Y. Kwon et al.   FASEB JOURNAL

Regulation of alkaline phosphatase by 1,25-dihydroxyvitamin D3 and ascorbic acid in bone-derived cells

(2010) Renny T. Franceschi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Neural Crest-Specific Loss ofPrkar1aCauses Perinatal Lethality Resulting from Defects in Intramembranous Ossification

(2010) Georgette N. Jones et al.   MOLECULAR ENDOCRINOLOGY

Kif3a Deficiency Reverses the Skeletal Abnormalities in Pkd1 Deficient Mice by Restoring the Balance Between Osteogenesis and Adipogenesis

(2010) Ni Qiu et al.   PLoS One

Alternate protein kinase A activity identifies a unique population of stromal cells in adult bone

(2010) K. M. Tsang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conditional Disruption ofPkd1in Osteoblasts Results in Osteopenia Due to Direct Impairment of Bone Formation

(2009) Zhousheng Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

cAMP activation by PACAP/VIP stimulates IL-6 release and inhibits osteoblastic differentiation through VPAC2 receptor in osteoblastic MC3T3 cells

(2009) Azusa Nagata et al.   JOURNAL OF CELLULAR PHYSIOLOGY

High glucose stimulates adipogenic and inhibits osteogenic differentiation in MG-63 cells through cAMP/protein kinase A/extracellular signal-regulated kinase pathway

(2009) Weiwei Wang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Polycystic Kidney Disease

(2008) Peter C. Harris et al.   Annual Review of Medicine

Polycystin-1 Regulates Skeletogenesis through Stimulation of the Osteoblast-specific Transcription FactorRUNX2-II

(2008) Zhousheng Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of adipogenesis: a new job for the ER Ca2+pool

(2008) Jacopo Meldolesi   JOURNAL OF CELL BIOLOGY

Calreticulin inhibits commitment to adipocyte differentiation

(2008) Eva Szabo et al.   JOURNAL OF CELL BIOLOGY

A mouse model for polycystic kidney disease through a somatic in-frame deletion in the 5′ end of Pkd1

(2008) P.G. Starremans et al.   KIDNEY INTERNATIONAL

cAMP/PKA Regulates Osteogenesis, Adipogenesis and Ratio of RANKL/OPG mRNA Expression in Mesenchymal Stem Cells by Suppressing Leptin

(2008) Der-Chih Yang et al.   PLoS One