Laminopathies and lamin-associated signaling pathways

Structural Analysis of the Smad2−MAN1 Interaction That Regulates Transforming Growth Factor-β Signaling at the Inner Nuclear Membrane

(2010) Emilie Kondé et al.   BIOCHEMISTRY

Lamin complexes in the nuclear interior control progenitor cell proliferation and tissue homeostasis

(2010) Nana Naetar et al.   CELL CYCLE

Molecular mechanisms of centrosome and cytoskeleton anchorage at the nuclear envelope

(2010) Maria Schneider et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Prelamin A Acts to Accelerate Smooth Muscle Cell Senescence and Is a Novel Biomarker of Human Vascular Aging

(2010) Cassandra D. Ragnauth et al.   CIRCULATION

Genome–nuclear lamina interactions and gene regulation

(2010) Jop Kind et al.   CURRENT OPINION IN CELL BIOLOGY

Functional Coupling between the Extracellular Matrix and Nuclear Lamina by Wnt Signaling in Progeria

(2010) Lidia Hernandez et al.   DEVELOPMENTAL CELL

Phosphorylation statuses at different residues of lamin B2, B1, and A/C dynamically and independently change throughout the cell cycle

(2010) Takahisa Kuga et al.   EXPERIMENTAL CELL RESEARCH

LIM domain protein FHL1B interacts with PP2A catalytic β subunit - A novel cell cycle regulatory pathway

(2010) Chi-Hang Wong et al.   FEBS LETTERS

Requirement for Lamin B Receptor and Its Regulation by Importin β and Phosphorylation in Nuclear Envelope Assembly during Mitotic Exit

(2010) Xuelong Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Specific phosphorylation of Ser458 of A-type lamins in LMNA-associated myopathy patients

(2010) H. Mitsuhashi et al.   JOURNAL OF CELL SCIENCE

Genes, proteins and complexes: the multifaceted nature of FHL family proteins in diverse tissues

(2010) Thiruchelvi Shathasivam et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Puma is required for p53-induced depletion of adult stem cells

(2010) Dongping Liu et al.   NATURE CELL BIOLOGY

Myocardial Fibrosis in Hypertrophic Cardiomyopathy

(2010)   NEW ENGLAND JOURNAL OF MEDICINE

Defective Lamin A-Rb Signaling in Hutchinson-Gilford Progeria Syndrome and Reversal by Farnesyltransferase Inhibition

(2010) Jackleen Marji et al.   PLoS One

A molecular mechanism underlying the neural-specific defect in torsinA mutant mice

(2010) C. E. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function

(2010) G. Marino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Cellular Metabolism by Protein Lysine Acetylation

(2010) S. Zhao et al.   SCIENCE

Significance of host cell kinases in herpes simplex virus type 1 egress and lamin-associated protein disassembly from the nuclear lamina

(2010) Natalie R. Leach et al.   VIROLOGY

Diseases of the Nuclear Envelope

(2010) H. J. Worman et al.   Cold Spring Harbor Perspectives in Biology

Autosomal-Dominant Distal Myopathy Associated with a Recurrent Missense Mutation in the Gene Encoding the Nuclear Matrix Protein, Matrin 3

(2009) Jan Senderek et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cell Cycle-Dependent Phosphorylation of MAN1†

(2009) Yasuhiro Hirano et al.   BIOCHEMISTRY

Impairment of bidirectional synaptic plasticity in the striatum of a mouse model of DYT1 dystonia: role of endogenous acetylcholine

(2009) Giuseppina Martella et al.   BRAIN

Identification of an emerin–β-catenin complex in the heart important for intercalated disc architecture and β-catenin localisation

(2009) Matthew A. Wheeler et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Lamina-Associated Polypeptide 2α Loss Impairs Heart Function and Stress Response in Mice

(2009) Ivana Gotic et al.   CIRCULATION RESEARCH

The Nuclear Envelope as a Signaling Node in Development and Disease

(2009) William T. Dauer et al.   DEVELOPMENTAL CELL

SLIMMER (FHL1B/KyoT3) Interacts with the Proapoptotic Protein Siva-1 (CD27BP) and Delays Skeletal Myoblast Apoptosis

(2009) Denny L. Cottle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian SUN Protein Interaction Networks at the Inner Nuclear Membrane and Their Role in Laminopathy Disease Processes

(2009) Farhana Haque et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of A-type lamins in signaling, transcription, and chromatin organization

(2009) Vicente Andrés et al.   JOURNAL OF CELL BIOLOGY

Dynamic complexes of A-type lamins and emerin influence adipogenic capacity of the cell via nucleocytoplasmic distribution of  -catenin

(2009) K. Tilgner et al.   JOURNAL OF CELL SCIENCE

Dynamics and molecular interactions of linker of nucleoskeleton and cytoskeleton (LINC) complex proteins

(2009) C. Ostlund et al.   JOURNAL OF CELL SCIENCE

Tyrosine phosphorylation of nuclear-membrane protein emerin by Src, Abl and other kinases

(2009) K. E. Tifft et al.   JOURNAL OF CELL SCIENCE

Nuclear lamins: key regulators of nuclear structure and activities

(2009) Miron Prokocimer et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Matrin 3: Chromosomal distribution and protein interactions

(2009) Michael J. Zeitz et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

A-type lamins and signaling: The PI 3-kinase/Akt pathway moves forward

(2009) Sandra Marmiroli et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Induction of a Massive Endoplasmic Reticulum and Perinuclear Space Expansion by Expression of Lamin B Receptor Mutants and the Related Sterol Reductases TM7SF2 and DHCR7

(2009) Monika Zwerger et al.   MOLECULAR BIOLOGY OF THE CELL

Barrier-to-Autointegration Factor Proteome Reveals Chromatin-Regulatory Partners

(2009) Rocío Montes de Oca et al.   PLoS One

Loss of LAP2α Delays Satellite Cell Differentiation and Affects Postnatal Fiber-Type Determination

(2009) Ivana Gotic et al.   STEM CELLS

A novel phenotypic expression associated with a new mutation in LMNA gene, characterized by partial lipodystrophy, insulin resistance, aortic stenosis and hypertrophic cardiomyopathy

(2008) David Araújo-Vilar et al.   CLINICAL ENDOCRINOLOGY

Monogenic polycystic ovary syndrome due to a mutation in the lamin A/C gene is sensitive to thiazolidinediones but not to metformin

(2008) A Gambineri et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Prelamin A is involved in early steps of muscle differentiation

(2008) Cristina Capanni et al.   EXPERIMENTAL CELL RESEARCH

Differentiation of C2C12 myoblasts expressing lamin A mutated at a site responsible for Emery–Dreifuss muscular dystrophy is improved by inhibition of the MEK–ERK pathway and stimulation of the PI3-kinase pathway

(2008) Catherine Favreau et al.   EXPERIMENTAL CELL RESEARCH

The A- and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcription

(2008) T. Shimi et al.   GENES & DEVELOPMENT

Inhibition of extracellular signal-regulated kinase signaling to prevent cardiomyopathy caused by mutation in the gene encoding A-type lamins

(2008) A. Muchir et al.   HUMAN MOLECULAR GENETICS

Fast regulation of AP-1 activity through interaction of lamin A/C, ERK1/2, and c-Fos at the nuclear envelope

(2008) José María González et al.   JOURNAL OF CELL BIOLOGY

Identification of FHL1 as a regulator of skeletal muscle mass: implications for human myopathy

(2008) Belinda S. Cowling et al.   JOURNAL OF CELL BIOLOGY

Nuclear envelope defects cause stem cell dysfunction in premature-aging mice

(2008) Jesús Espada et al.   JOURNAL OF CELL BIOLOGY

Sumoylation regulates lamin A function and is lost in lamin A mutants associated with familial cardiomyopathies

(2008) Yu-Qian Zhang et al.   JOURNAL OF CELL BIOLOGY

TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton

(2008) F. C. Nery et al.   JOURNAL OF CELL SCIENCE

Effects of prelamin A processing inhibitors on the differentiation and activity of human osteoclasts

(2008) Nicoletta Zini et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Remodelling of the nuclear lamina during human cytomegalovirus infection: role of the viral proteins pUL50 and pUL53

(2008) D. Camozzi et al.   JOURNAL OF GENERAL VIROLOGY

Lamin A Ser404 Is a Nuclear Target of Akt Phosphorylation in C2C12 Cells

(2008) Vittoria Cenni et al.   JOURNAL OF PROTEOME RESEARCH

Analysis of Prelamin A Biogenesis Reveals the Nucleus to be a CaaX Processing Compartment

(2008) Jemima Barrowman et al.   MOLECULAR BIOLOGY OF THE CELL

Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing

(2008) Paola Scaffidi et al.   NATURE CELL BIOLOGY

Loss of nucleoplasmic LAP2α–lamin A complexes causes erythroid and epidermal progenitor hyperproliferation

(2008) Nana Naetar et al.   NATURE CELL BIOLOGY

Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging

(2008) Ignacio Varela et al.   NATURE MEDICINE

A quantitative atlas of mitotic phosphorylation

(2008) N. Dephoure et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA