Keratinocytes synthesize and activate cortisol

Cortisol Synthesis in Epidermis Is Induced by IL-1 and Tissue Injury

(2011) Sasa Vukelic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Steroid synthesis by primary human keratinocytes; implications for skin disease

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The glucocorticoid-activating enzyme 11β-hydroxysteroid dehydrogenase type 1 has broad substrate specificity: Physiological and toxicological considerations

(2010) Alex Odermatt et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The 11 -hydroxysteroid dehydrogenase enzymes--arbiters of the effects of glucocorticoids in synovium and bone

(2010) K. Raza et al.   RHEUMATOLOGY

Desmosomal interactome in keratinocytes: a systems biology approach leading to an understanding of the pathogenesis of skin disease

(2009) Nicola Cirillo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Kinetic Complexity of the Global Response to Glucocorticoid Receptor Action

(2009) Sam John et al.   ENDOCRINOLOGY

Inhibition of 11β–hydroxysteroid dehydrogenase type II selectively blocks the tumor COX-2 pathway and suppresses colon carcinogenesis in mice and humans

(2009) Ming-Zhi Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Evidence of Key Role of Cdk2 Overexpression in Pemphigus Vulgaris

(2008) Alessandro Lanza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genomic and nongenomic effects of glucocorticoids

(2008) Cindy Stahn et al.   Nature clinical practice. Rheumatology