Reduction of PINK1 or DJ-1 impair mitochondrial motility in neurites and alter ER-mitochondria contacts

PINK1 regulates mitochondrial trafficking in dendrites of cortical neurons through mitochondrial PKA

(2017) Tania Das Banerjee et al.   JOURNAL OF NEUROCHEMISTRY

From dysfunctional endoplasmic reticulum-mitochondria coupling to neurodegeneration

(2017) Zoi Erpapazoglou et al.   NEUROCHEMISTRY INTERNATIONAL

PINK1-mediated phosphorylation of LETM1 regulates mitochondrial calcium transport and protects neurons against mitochondrial stress

(2017) En Huang et al.   Nature Communications

Inhibition of the mitochondrial calcium uniporter rescues dopaminergic neurons inpink1−/−zebrafish

(2016) Smijin Soman et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Miro phosphorylation sites regulate Parkin recruitment and mitochondrial motility

(2016) Evgeny Shlevkov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

There's Something Wrong with my MAM; the ER–Mitochondria Axis and Neurodegenerative Diseases

(2016) Sebastien Paillusson et al.   TRENDS IN NEUROSCIENCES

DJ1 represses glycolysis and cell proliferation by transcriptionally up-regulatingpink1

(2015) Raquel Requejo-Aguilar et al.   BIOCHEMICAL JOURNAL

The Organization of Mitochondrial Quality Control and Life Cycle in the Nervous System In Vivo in the Absence of PINK1

(2015) S. Devireddy et al.   JOURNAL OF NEUROSCIENCE

Enhanced parkin levels favor ER-mitochondria crosstalk and guarantee Ca2+ transfer to sustain cell bioenergetics

(2013) Tito Calì et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Parkinson disease-related protein DJ-1 counteracts mitochondrial impairment induced by the tumour suppressor protein p53 by enhancing endoplasmic reticulum-mitochondria tethering

(2013) D. Ottolini et al.   HUMAN MOLECULAR GENETICS

Neuronal vulnerability, pathogenesis, and Parkinson's disease

(2013) David Sulzer et al.   MOVEMENT DISORDERS

Parkin- and PINK1-Dependent Mitophagy in Neurons: Will the Real Pathway Please Stand Up?

(2013) Karl Grenier et al.   Frontiers in Neurology

The pathways of mitophagy for quality control and clearance of mitochondria

(2012) G Ashrafi et al.   CELL DEATH AND DIFFERENTIATION

Spatial Parkin Translocation and Degradation of Damaged Mitochondria via Mitophagy in Live Cortical Neurons

(2012) Qian Cai et al.   CURRENT BIOLOGY

Microtubule Affinity-regulating Kinase 2 (MARK2) Turns on Phosphatase and Tensin Homolog (PTEN)-induced Kinase 1 (PINK1) at Thr-313, a Mutation Site in Parkinson Disease

(2012) Dorthe Matenia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of mitochondrial permeability transition pore by PINK1

(2012) Clement A Gautier et al.   Molecular Neurodegeneration

Parkinson's Disease–Associated Kinase PINK1 Regulates Miro Protein Level and Axonal Transport of Mitochondria

(2012) Song Liu et al.   PLoS Genetics

PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility

(2011) Xinnan Wang et al.   CELL

DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy

(2010) Kelly Jean Thomas et al.   HUMAN MOLECULAR GENETICS

Reduced Basal Autophagy and Impaired Mitochondrial Dynamics Due to Loss of Parkinson's Disease-Associated Protein DJ-1

(2010) Guido Krebiehl et al.   PLoS One

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Pink1 Forms a Multiprotein Complex with Miro and Milton, Linking Pink1 Function to Mitochondrial Trafficking†

(2009) Andreas Weihofen et al.   BIOCHEMISTRY

Mitochondria, calcium and cell death: A deadly triad in neurodegeneration

(2009) Fulvio Celsi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial ‘kiss-and-run’: interplay between mitochondrial motility and fusion–fission dynamics

(2009) Xingguo Liu et al.   EMBO JOURNAL

PINK1 function in health and disease

(2009) Emma Deas et al.   EMBO Molecular Medicine

Loss of Parkin or PINK1 Function Increases Drp1-dependent Mitochondrial Fragmentation

(2009) A. Kathrin Lutz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission

(2009) Ruben K. Dagda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Drosophila Miro Is Required for Both Anterograde and Retrograde Axonal Mitochondrial Transport

(2009) G. J. Russo et al.   JOURNAL OF NEUROSCIENCE

PINK1-Associated Parkinson's Disease Is Caused by Neuronal Vulnerability to Calcium-Induced Cell Death

(2009) Sonia Gandhi et al.   MOLECULAR CELL

Mitochondrial Alterations in PINK1 Deficient Cells Are Influenced by Calcineurin-Dependent Dephosphorylation of Dynamin-Related Protein 1

(2009) Anna Sandebring et al.   PLoS One

Calcium regulation of mitochondria motility and morphology

(2008) Danny V. Jeyaraju et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Positioning mitochondrial plasticity within cellular signaling cascades

(2008) Vincent Soubannier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Characterization of PINK1 processing, stability, and subcellular localization

(2008) William Lin et al.   JOURNAL OF NEUROCHEMISTRY

Mitochondrial alterations in Parkinson’s disease: new clues

(2008) Miquel Vila et al.   JOURNAL OF NEUROCHEMISTRY

Mitochondrial localization of DJ-1 leads to enhanced neuroprotection

(2008) Eunsung Junn et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Mitochondria in the aetiology and pathogenesis of Parkinson's disease

(2008) Anthony HV Schapira   LANCET NEUROLOGY

RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways

(2008) M. P. van der Brug et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery

(2008) Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase

(2008) M. Saotome et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA