Berberine ameliorates cartilage degeneration in interleukin-1β-stimulated rat chondrocytes and in a rat model of osteoarthritisviaAkt signalling

Sustained release of PTH(1–34) from PLGA microspheres suppresses osteoarthritis progression in rats

(2012) Rajalakshmanan Eswaramoorthy et al.   Acta Biomaterialia

Hypoxia-inducible factor 1 mediates the anti-apoptosis of berberine in neurons during hypoxia/ischemia

(2012) Q. Zhang et al.   ACTA PHYSIOLOGICA HUNGARICA

Dkk-1 expression in chondrocytes inhibits experimental osteoarthritic cartilage destruction in mice

(2012) Hwanhee Oh et al.   ARTHRITIS AND RHEUMATISM

Requirement of the phosphatidylinositol 3-kinase/Akt signaling pathway for the effect of nicotine on interleukin-1beta-induced chondrocyte apoptosis in a rat model of osteoarthritis

(2012) Xinpeng Zheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Increased apoptosis in human knee osteoarthritis cartilage related to the expression of protein kinase B and protein kinase Cα in chondrocytes

(2012) Qingzhi Chen et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

Berberine, an Isoquinoline Alkaloid, Inhibits the Metastatic Potential of Breast Cancer Cells via Akt Pathway Modulation

(2012) Han-Peng Kuo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Nuclear-to-cytoplasmic Relocalization of the Proliferating Cell Nuclear Antigen (PCNA) during Differentiation Involves a Chromosome Region Maintenance 1 (CRM1)-dependent Export and Is a Prerequisite for PCNA Antiapoptotic Activity in Mature Neutrophils

(2012) Dikra Bouayad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unknown

(2012) Anja Weimer et al.   MOLECULAR MEDICINE

Reversal of PCNA Ubiquitylation by Ubp10 in Saccharomyces cerevisiae

(2012) Alfonso Gallego-Sánchez et al.   PLoS Genetics

Hydrophobic Motif Phosphorylation Is Not Required for Activation Loop Phosphorylation of p70 Ribosomal Protein S6 Kinase 1 (S6K1)

(2011) Malik M. Keshwani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Berberine Chloride Mediates Its Anti-Leishmanial Activity via Differential Regulation of the Mitogen Activated Protein Kinase Pathway in Macrophages

(2011) Piu Saha et al.   PLoS One

Effect of Berberine on Cell Survival in the Developing Rat Brain Damaged by MK-801

(2011) Taehwan Lee et al.   Experimental Neurobiology

Prevention of cartilage degeneration and restoration of chondroprotection by lubricin tribosupplementation in the rat following anterior cruciate ligament transection

(2010) Gregory D. Jay et al.   ARTHRITIS AND RHEUMATISM

Chondrocyte death by apoptosis is associated with the initiation and severity of articular cartilage degradation

(2010) Carla M. THOMAS et al.   International Journal of Rheumatic Diseases

Biology and pathology of Rho GTPase, PI-3 kinase-Akt, and MAP kinase signaling pathways in chondrocytes

(2010) Frank Beier et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: The cellular mechanism

(2010) Ning Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Relation of low-intensity pulsed ultrasound to the cell density of scaffold-free cartilage in a high-density static semi-open culture system

(2010) Kazuhiro Uenaka et al.   JOURNAL OF ORTHOPAEDIC SCIENCE

Hypoxia-inducible factor-2α is a catabolic regulator of osteoarthritic cartilage destruction

(2010) Siyoung Yang et al.   NATURE MEDICINE

Basic methods in histopathology of joint tissues

(2010) N. Schmitz et al.   OSTEOARTHRITIS AND CARTILAGE

Baekjeolyusin-tang and its active component berberine block the release of collagen and proteoglycan from IL-1β-stimulated rabbit cartilage and down-regulate matrix metalloproteinases in rabbit chondrocytes

(2010) Phil-Dong Moon et al.   PHYTOTHERAPY RESEARCH

Protective Effects of Berberine in an Experimental Rat Osteoarthritis Model

(2010) Peng-fei Hu et al.   PHYTOTHERAPY RESEARCH

Increased expression of the Akt/PKB inhibitor TRB3 in osteoarthritic chondrocytes inhibits insulin-like growth factor 1-mediated cell survival and proteoglycan synthesis

(2009) John D. Cravero et al.   ARTHRITIS AND RHEUMATISM

Berberine Protects Mesenchymal Stem Cells against Hypoxia-Induced Apoptosis in Vitro

(2009) Wei Zhang et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Mechanism of PDK1-catalyzed Thr-229 Phosphorylation of the S6K1 Protein Kinase

(2009) Malik M. Keshwani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative Stress Inhibits Insulin-like Growth Factor-I Induction of Chondrocyte Proteoglycan Synthesis through Differential Regulation of Phosphatidylinositol 3-Kinase-Akt and MEK-ERK MAPK Signaling Pathways

(2009) Weihong Yin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The effect of hyaluronic acid on IL-1β-induced chondrocyte apoptosis in a rat model of osteoarthritis

(2008) Pang-Hu Zhou et al.   JOURNAL OF ORTHOPAEDIC RESEARCH