Class IIa HDACs: from important roles in differentiation to possible implications in tumourigenesis

Inhibition of androgen receptor activity by histone deacetylase 4 through receptor SUMOylation

(2011) Y Yang et al.   ONCOGENE

microRNA-22, downregulated in hepatocellular carcinoma and correlated with prognosis, suppresses cell proliferation and tumourigenicity

(2010) J Zhang et al.   BRITISH JOURNAL OF CANCER

research paper: Differential expression of HDAC3, HDAC7 and HDAC9 is associated with prognosis and survival in childhood acute lymphoblastic leukaemia

(2010) Daniel Antunes Moreno et al.   BRITISH JOURNAL OF HAEMATOLOGY

Suppression of Cyclin D1 by Hypoxia-Inducible Factor-1 via Direct Mechanism Inhibits the Proliferation and 5-Fluorouracil-Induced Apoptosis of A549 Cells

(2010) W. Wen et al.   CANCER RESEARCH

Histone Deacetylase 7 Controls Endothelial Cell Growth Through Modulation of β-Catenin

(2010) Andriana Margariti et al.   CIRCULATION RESEARCH

HDAC5 and HDAC9 in Medulloblastoma: Novel Markers for Risk Stratification and Role in Tumor Cell Growth

(2010) T. Milde et al.   CLINICAL CANCER RESEARCH

Histone Deacetylase 9 (HDAC9) Regulates the Functions of the ATDC (TRIM29) Protein

(2010) Zhigang Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian target of rapamycin regulates miRNA-1 and follistatin in skeletal myogenesis

(2010) Yuting Sun et al.   JOURNAL OF CELL BIOLOGY

Histone Demethylase LSD1 Regulates Neural Stem Cell Proliferation

(2010) G. Sun et al.   MOLECULAR AND CELLULAR BIOLOGY

Ubiquitin-dependent degradation of HDAC4, a new regulator of random cell motility

(2010) Nadia Cernotta et al.   MOLECULAR BIOLOGY OF THE CELL

PKA phosphorylates histone deacetylase 5 and prevents its nuclear export, leading to the inhibition of gene transcription and cardiomyocyte hypertrophy

(2010) C. H. Ha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PiggyBac Transposon Mutagenesis: A Tool for Cancer Gene Discovery in Mice

(2010) R. Rad et al.   SCIENCE

HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells

(2009) C. Urbich et al.   BLOOD

FOXP3 Up-regulates p21 Expression by Site-Specific Inhibition of Histone Deacetylase 2/Histone Deacetylase 4 Association to the Locus

(2009) R. Liu et al.   CANCER RESEARCH

Loss of Histone Deacetylase 4 Causes Segregation Defects during Mitosis of p53-Deficient Human Tumor Cells

(2009) B. Cadot et al.   CANCER RESEARCH

The role of oxysterol binding protein-related protein 5 in pancreatic cancer

(2009) Shinji Ishikawa et al.   CANCER SCIENCE

A Role of DNA-PK for the Metabolic Gene Regulation in Response to Insulin

(2009) Roger H.F. Wong et al.   CELL

Myocyte Enhancer Factor 2 and Class II Histone Deacetylases Control a Gender-Specific Pathway of Cardioprotection Mediated by the Estrogen Receptor

(2009) Eva van Rooij et al.   CIRCULATION RESEARCH

Splicing of HDAC7 modulates the SRF-myocardin complex during stem-cell differentiation towards smooth muscle cells

(2009) A. Margariti et al.   JOURNAL OF CELL SCIENCE

A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans

(2009) Hui Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Histone Deacetylase 7 and FoxA1 in Estrogen-Mediated Repression of RPRM

(2009) S. Malik et al.   MOLECULAR AND CELLULAR BIOLOGY

Parathyroid Hormone-Related Peptide Represses Chondrocyte Hypertrophy through a Protein Phosphatase 2A/Histone Deacetylase 4/MEF2 Pathway

(2009) E. Kozhemyakina et al.   MOLECULAR AND CELLULAR BIOLOGY

MicroRNA-206 Delays ALS Progression and Promotes Regeneration of Neuromuscular Synapses in Mice

(2009) A. H. Williams et al.   SCIENCE

Histones: Annotating Chromatin

(2008) Eric I. Campos et al.   Annual Review of Genetics

YY1 restrained cell senescence through repressing the transcription of p16

(2008) Xiuli Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cotreatment with BCL-2 antagonist sensitizes cutaneous T-cell lymphoma to lethal action of HDAC7-Nur77-based mechanism

(2008) J. Chen et al.   BLOOD

Differential expression of 12 histone deacetylase (HDAC) genes in astrocytomas and normal brain tissue: class II and IV are hypoexpressed in glioblastomas

(2008) Agda KB Lucio-Eterovic et al.   BMC CANCER

HDAC expression and clinical prognosis in human malignancies

(2008) Wilko Weichert   CANCER LETTERS

TBX3 Is Overexpressed in Breast Cancer and Represses p14ARF by Interacting with Histone Deacetylases

(2008) W. Yarosh et al.   CANCER RESEARCH

Methylation Mediated Silencing of MicroRNA-1 Gene and Its Role in Hepatocellular Carcinogenesis

(2008) J. Datta et al.   CANCER RESEARCH

A Redox-Dependent Pathway for Regulating Class II HDACs and Cardiac Hypertrophy

(2008) Tetsuro Ago et al.   CELL

Transcriptional activation of hypoxia-inducible factor-1α by HDAC4 and HDAC5 involves differential recruitment of p300 and FIH-1

(2008) Hee-Won Seo et al.   FEBS LETTERS

Structural and Functional Analysis of the Human HDAC4 Catalytic Domain Reveals a Regulatory Structural Zinc-binding Domain

(2008) Matthew J. Bottomley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human HDAC7 Harbors a Class IIa Histone Deacetylase-specific Zinc Binding Motif and Cryptic Deacetylase Activity

(2008) Anja Schuetz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Kinase D-dependent Phosphorylation and Nuclear Export of Histone Deacetylase 5 Mediates Vascular Endothelial Growth Factor-induced Gene Expression and Angiogenesis

(2008) Chang Hoon Ha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Down-regulation of Micro-RNA-1 (miR-1) in Lung Cancer

(2008) Mohd W. Nasser et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspase-8 Cleaves Histone Deacetylase 7 and Abolishes Its Transcription Repressor Function

(2008) Fiona L. Scott et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bone Morphogenic Protein 2 Activates Protein Kinase D to Regulate Histone Deacetylase 7 Localization and Repression of Runx2

(2008) Eric D. Jensen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone deacetylase 5 represses the transcription of cyclin D3

(2008) Sangita Roy et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Protein Kinase D1 Stimulates MEF2 Activity in Skeletal Muscle and Enhances Muscle Performance

(2008) M.-S. Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone Deacetylase 5 Acquires Calcium/Calmodulin-Dependent Kinase II Responsiveness by Oligomerization with Histone Deacetylase 4

(2008) J. Backs et al.   MOLECULAR AND CELLULAR BIOLOGY

HDAC4 Promotes Growth of Colon Cancer Cells via Repression of p21

(2008) Andrew J. Wilson et al.   MOLECULAR BIOLOGY OF THE CELL

Signal-dependent Regulation of Transcription by Histone Deacetylase 7 Involves Recruitment to Promyelocytic Leukemia Protein Nuclear Bodies

(2008) Chengzhuo Gao et al.   MOLECULAR BIOLOGY OF THE CELL

YY1 Protects Cardiac Myocytes from Pathologic Hypertrophy by Interacting with HDAC5

(2008) Carmen C. Sucharov et al.   MOLECULAR BIOLOGY OF THE CELL

A Histone Deacetylase 4/Myogenin Positive Feedback Loop Coordinates Denervation-dependent Gene Induction and Suppression

(2008) Huibin Tang et al.   MOLECULAR BIOLOGY OF THE CELL

Specific Activity of Class II Histone Deacetylases in Human Breast Cancer Cells

(2008) V. Duong et al.   MOLECULAR CANCER RESEARCH

AKAP-Lbc Mobilizes a Cardiac Hypertrophy Signaling Pathway

(2008) Graeme K. Carnegie et al.   MOLECULAR CELL

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

(2008) Michael Haberland et al.   NATURE REVIEWS GENETICS

The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

(2008) Xiang-Jiao Yang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

HDAC4 represses p21WAF1/Cip1 expression in human cancer cells through a Sp1-dependent, p53-independent mechanism

(2008) D Mottet et al.   ONCOGENE

Protein phosphatase 2A controls the activity of histone deacetylase 7 during T cell apoptosis and angiogenesis

(2008) M. Martin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Requirement of protein kinase D1 for pathological cardiac remodeling

(2008) J. Fielitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7

(2008) S. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PP2A Regulates HDAC4 Nuclear Import

(2007) Gabriela Paroni et al.   MOLECULAR BIOLOGY OF THE CELL