The thyroid hormone receptor β induces DNA damage and premature senescence

53BP1 Mediates Productive and Mutagenic DNA Repair through Distinct Phosphoprotein Interactions

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A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice

(2013) Cristina Escribano-Díaz et al.   MOLECULAR CELL

53BP1 Regulates DSB Repair Using Rif1 to Control 5' End Resection

(2013) M. Zimmermann et al.   SCIENCE

Thyroid hormone receptors and cancer

(2012) Won Gu Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Thyroid hormone receptors, cell growth and differentiation

(2012) Angel Pascual et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Pathological neoangiogenesis depends on oxidative stress regulation by ATM

(2012) Yuji Okuno et al.   NATURE MEDICINE

Outcome of Graves' Orbitopathy after Total Thyroid Ablation and Glucocorticoid Treatment: Follow-Up of a Randomized Clinical Trial

(2011) Marenza Leo et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

Familial Longevity Is Associated with Decreased Thyroid Function

(2010) M. P. Rozing et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Mitochondrial uncoupling and lifespan

(2010) Shona A. Mookerjee et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance

(2010) Miguel López et al.   NATURE MEDICINE

Thyroid hormone receptor β1 domains responsible for the antagonism with the ras oncogene: role of corepressors

(2010) S García-Silva et al.   ONCOGENE

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

(2010) A. Alexander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extreme Longevity Is Associated with Increased Serum Thyrotropin

(2009) Gil Atzmon et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Essential Role for DNA-PKcs in DNA Double-Strand Break Repair and Apoptosis in ATM-Deficient Lymphocytes

(2009) Elsa Callén et al.   MOLECULAR CELL

Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity

(2009) George A. Garinis et al.   NATURE CELL BIOLOGY

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY

Thyroid receptor: roles in cancer

(2009) Ana Aranda et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Endocrine function in naturally long-living small mammals

(2008) Rochelle Buffenstein et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Thyroid Hormone Activates Adenosine 5′-Monophosphate-Activated Protein Kinase via Intracellular Calcium Mobilization and Activation of Calcium/Calmodulin-Dependent Protein Kinase Kinase-β

(2008) Masako Yamauchi et al.   MOLECULAR ENDOCRINOLOGY

Puzzles, promises and a cure for ageing

(2008) Jan Vijg et al.   NATURE

Etoposide Induces ATM-Dependent Mitochondrial Biogenesis through AMPK Activation

(2008) Xuan Fu et al.   PLoS One