Aberrant substrate engagement of the ER translocon triggers degradation by the Hrd1 ubiquitin ligase

Membrane Protein Insertion at the Endoplasmic Reticulum

(2011) Sichen Shao et al.   Annual Review of Cell and Developmental Biology

Ubiquitination regulates the assembly of VLDL in HepG2 cells and is the committing step of the apoB-100 ERAD pathway

(2011) Eric A. Fisher et al.   JOURNAL OF LIPID RESEARCH

Translocation channel gating kinetics balances protein translocation efficiency with signal sequence recognition fidelity

(2011) Steven F. Trueman et al.   MOLECULAR BIOLOGY OF THE CELL

Functional and genomic analyses of blocked protein O-mannosylation in baker's yeast

(2011) Javier Arroyo et al.   MOLECULAR MICROBIOLOGY

Protein translocation across the ER membrane

(2010) Richard Zimmermann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Retrotranslocation of a Misfolded Luminal ER Protein by the Ubiquitin-Ligase Hrd1p

(2010) Pedro Carvalho et al.   CELL

Modularity of the Hrd1 ERAD complex underlies its diverse client range

(2010) Kazue Kanehara et al.   JOURNAL OF CELL BIOLOGY

Mechanisms Targeting Apolipoprotein B100 to Proteasomal Degradation

(2009) Angela C. Rutledge et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Sec61p is part of the endoplasmic reticulum-associated degradation machinery

(2009) Antje Schäfer et al.   EMBO JOURNAL

Protein O-mannosylation: Conserved from bacteria to humans

(2009) M. Lommel et al.   GLYCOBIOLOGY

Usa1p Is Required for Optimal Function and Regulation of the Hrd1p Endoplasmic Reticulum-associated Degradation Ubiquitin Ligase

(2009) Sarah M. Carroll et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Usa1 Functions as a Scaffold of the HRD-Ubiquitin Ligase

(2009) Sabine C. Horn et al.   MOLECULAR CELL

Misfolded Membrane Proteins Are Specifically Recognized by the Transmembrane Domain of the Hrd1p Ubiquitin Ligase

(2009) Brian K. Sato et al.   MOLECULAR CELL

The ER-associated degradation component Der1p and its homolog Dfm1p are contained in complexes with distinct cofactors of the ATPase Cdc48p

(2008) Veit Goder et al.   FEBS LETTERS

Degradation of a Cytosolic Protein Requires Endoplasmic Reticulum-associated Degradation Machinery

(2008) Meredith Boyle Metzger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sec61p Is Required for ERAD-L

(2008) Martin Willer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Sec61p in the ER-associated degradation of short-lived transmembrane proteins

(2008) Daniel C. Scott et al.   JOURNAL OF CELL BIOLOGY

The AAA-ATPase p97 facilitates degradation of apolipoprotein B by the ubiquitin-proteasome pathway

(2008) Eric A. Fisher et al.   JOURNAL OF LIPID RESEARCH

Diversity of degradation signals in the ubiquitin–proteasome system

(2008) Tommer Ravid et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY