Progeria: Translational insights from cell biology

Automated image analysis of nuclear shape: What can we learn from a prematurely aged cell?

(2016) Meghan K. Driscoll et al.   Aging-US

Naive adult stem cells from patients with Hutchinson-Gilford progeria syndrome express low levels of progerin in vivo

(2012) V. Wenzel et al.   Biology Open

Mechanisms of Premature Vascular Aging in Children With Hutchinson-Gilford Progeria Syndrome

(2011) Marie Gerhard-Herman et al.   HYPERTENSION

Hutchinson-gilford progeria is a skeletal dysplasia

(2011) Catherine M Gordon et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts

(2011) Kan Cao et al.   JOURNAL OF CLINICAL INVESTIGATION

Highlights of the 2007 Progeria Research Foundation Scientific Workshop: Progress in Translational Science

(2011) L. B. Gordon et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome

(2011) Guang-Hui Liu et al.   NATURE

Differential Temporal and Spatial Progerin Expression during Closure of the Ductus Arteriosus in Neonates

(2011) Regina Bökenkamp et al.   PLoS One

Splicing-Directed Therapy in a New Mouse Model of Human Accelerated Aging

(2011) F. G. Osorio et al.   Science Translational Medicine

Rapamycin Reverses Cellular Phenotypes and Enhances Mutant Protein Clearance in Hutchinson-Gilford Progeria Syndrome Cells

(2011) K. Cao et al.   Science Translational Medicine

Cardiovascular Pathology in Hutchinson-Gilford Progeria: Correlation With the Vascular Pathology of Aging

(2010) Michelle Olive et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A Human iPSC Model of Hutchinson Gilford Progeria Reveals Vascular Smooth Muscle and Mesenchymal Stem Cell Defects

(2010) Jinqiu Zhang et al.   Cell Stem Cell

Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging

(2008) Ignacio Varela et al.   NATURE MEDICINE

Phenotype and Course of Hutchinson–Gilford Progeria Syndrome

(2008) Melissa A. Merideth et al.   NEW ENGLAND JOURNAL OF MEDICINE

A farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model

(2008) B. C. Capell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA