Structural basis of the junctional anchorage of the cerebral cavernous malformations complex

Developmental timing of CCM2 loss influences cerebral cavernous malformations in mice

(2011) Gwénola Boulday et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A mechanism of Rap1-induced stabilization of endothelial cell–cell junctions

(2011) Jian J. Liu et al.   MOLECULAR BIOLOGY OF THE CELL

Fasudil Decreases Lesion Burden in a Murine Model of Cerebral Cavernous Malformation Disease

(2011) David A. McDonald et al.   STROKE

Recent insights into cerebral cavernous malformations: a complex jigsaw puzzle under construction

(2010) Eva Faurobert et al.   FEBS Journal

CCM1 regulates vascular-lumen organization by inducing endothelial polarity

(2010) M. G. Lampugnani et al.   JOURNAL OF CELL SCIENCE

Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity

(2010) Rebecca A. Stockton et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Organizing the cell cortex: the role of ERM proteins

(2010) Richard G. Fehon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rap1 and its effector KRIT1/CCM1 regulate  -catenin signaling

(2009) A. J. Glading et al.   Disease Models & Mechanisms

The structure of an integrin/talin complex reveals the basis of inside-out signal transduction

(2009) Nicholas J Anthis et al.   EMBO JOURNAL

The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases

(2009) Kevin J Whitehead et al.   NATURE MEDICINE

Regulation of cardiovascular development and integrity by the heart of glass–cerebral cavernous malformation protein pathway

(2009) Benjamin Kleaveland et al.   NATURE MEDICINE

Biology of Vascular Malformations of the Brain

(2009) Gabrielle G. Leblanc et al.   STROKE

Structural and functional differences between KRIT1A and KRIT1B isoforms: A framework for understanding CCM pathogenesis

(2008) Floriana Francalanci et al.   EXPERIMENTAL CELL RESEARCH

ccm1 cell autonomously regulates endothelial cellular morphogenesis and vascular tubulogenesis in zebrafish

(2008) Benjamin M. Hogan et al.   HUMAN MOLECULAR GENETICS