Article
Medicine, General & Internal
Poyin Huang, Yi-Chiung Hsu, Chien-Hsun Li, Sun-Wung Hsieh, Kuo-Wei Lee, Kun-Han Wu, Wen-Ching Chen, Chung-Wei Lin, Chun-Hung Chen
Summary: In this study, 100 dysphagia patients were evaluated using various methods and followed up to assess the association between dysphagia severity and subsequent pneumonia. Only VF-DSS was significantly associated with pneumonia, while other evaluations showed no correlation. Therefore, VF-DSS can be used to predict the occurrence of pneumonia in dysphagia patients.
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES
(2023)
Article
Medicine, Research & Experimental
Joeke L. Nollet, Per Cajander, Lara F. Ferris, Jordache Ramjith, Taher Omari, Johanna Savilampi
Summary: The study aimed to investigate the effects of bolus volume and viscosity on pharyngeal swallow using circumferential pressure sensor technology and found that larger volumes increased intrabolus pressure and all upper esophageal sphincter metrics, while thicker viscosity decreased UES relaxation time and flow timing metrics. The use of this technology provides consistent results with previous reports, offering insights into aberrant pharyngo-esophageal motor responses over time.
Article
Computer Science, Artificial Intelligence
Zhenwei Zhang, Shitong Mao, James Coyle, Ervin Sejdic
Summary: A novel machine learning algorithm has been shown to detect key anatomical points needed for swallowing assessments in real-time with high accuracy, offering speech language pathologists more choices for efficient and accurate anatomic landmark localization.
MEDICAL IMAGE ANALYSIS
(2021)
Article
Medicine, General & Internal
Hyun-Il Kim, Yuna Kim, Bomin Kim, Dae Youp Shin, Seong Jae Lee, Sang-Il Choi
Summary: A deep learning model was designed in this study to detect and track hyoid bone movement more efficiently and accurately in VFSS analysis, showing improved performance compared to previous models.
Article
Otorhinolaryngology
Wen-Ching Chen, Chung-Wei Lin, Meng-Ni Wu, Yi-On Fong, Chun-Hung Chen, Sun-Wung Hsieh, Chih-Yin Elizabeth Chen, Poyin Huang
Summary: Post-stroke dysphagia (PSD) is the most common type of dysphagia, and severe PSD leads to poor outcomes. Various scales are used to assess the severity of PSD, but their consistencies are unknown. This study aims to investigate the consistencies among different scales to aid in the assessment of PSD.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2023)
Article
Medicine, Research & Experimental
Rebecca Leonard, Anna Miles, Lise Bakker, Jacqueline Allen
Summary: This study uses a novel X-ray imaging method to measure pharyngeal shortening during swallowing and reveals quantitative changes related to sex, size, and bolus type in healthy and swallow-impaired adults.
Article
Pediatrics
Jana Jancikova, Denisa Bezdekova, Petra Urbanova, Lucie Dohnalova, Petr Jabandziev, Miroslav Tedla, Zofia Frajkova, Jiri Jarkovsky, Milan Urik
Summary: This study aimed to identify relationships between specific symptoms reported in a clinical questionnaire and pathological signs observed on VFSS in children with swallowing disorders. The results showed correlation between certain symptoms and pathological signs, indicating that evaluating targeted questions is a reliable method for managing dysphagia and selecting patients for VFSS.
Article
Gastroenterology & Hepatology
Dustin A. Carlson, Jacqueline E. Prescott, Alexandra J. Baumann, Jacob M. Schauer, Amanda Krause, Erica N. Donnan, Wenjun Kou, Peter J. Kahrilas, John E. Pandolfino
Summary: FLIP panometry accurately identifies clinically relevant esophagogastric junction obstruction as defined by the Chicago Classification version 4.0 in patients evaluated for esophageal motor disorders. It is a valuable tool for assessing esophageal motility.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Oncology
Agata Gawryszuk, Hendrik P. Bijl, Arjen van der Schaaf, Nathalie Perdok, Jan Wedman, Irma M. Verdonck-de Leeuw, Rico N. Rinkel, Roel J. H. M. Steenbakkers, Johanna G. M. van den Hoek, Hans Paul van der Laan, Johannes A. Langendijk
Summary: This study evaluated swallowing disorders in HNC patients undergoing radiation therapy and found an increased risk of aspiration, with prediction models to aid in patient selection for baseline and follow-up VF examinations.
RADIOTHERAPY AND ONCOLOGY
(2021)
Article
Otorhinolaryngology
Ashwini M. Namasivayam-MacDonald, Naga Alomari, Lauren Attner, Rebecca D. Benjamin, Alexandra Chill, Samantha Doka, Rebekah Guastella, Jena Marchese, Stefania Oppedisano, Kathryn Ressa, Brianna E. Rider, Gracelynn K. Sandoval, Alexandra Soyfer, Riesa Thompson, Caitlin M. Walshe, Luis F. Riquelme
Summary: This study aimed to describe the pathophysiology of dysphagia in patients living with dementia by analyzing swallowing physiology data from a sample of 106 adults. Significant differences in various swallowing parameters were found compared to published norms, and unsafe swallowing and clinically significant residue were common. Associations between specific swallowing measures and dysfunction were identified, highlighting the need for further research on different variables affecting dysphagia in dementia patients.
Article
Clinical Neurology
Kenichiro Taira, Toshiyuki Yamamoto, Madoka Mori-Yoshimura, Kazuaki Sajima, Hotake Takizawa, Jun Shinmi, Yasushi Oya, Ichizo Nishino, Yuji Takahashi
Summary: The presence of cricopharyngeal bar (CPB) may indicate inclusion body myositis (IBM). In IBM patients with CPB, the upper esophagus becomes narrow like a bottleneck. This study provides new perspectives on dysphagia diagnosis through videofluoroscopy, particularly for IBM-related dysphagia.
JOURNAL OF NEUROLOGY
(2021)
Article
Gastroenterology & Hepatology
Boram Cha, Kyungmin Choi, Kee Wook Jung, Hwa Jung Kim, Ga Hee Kim, Hee Kyong Na, Ji Yong Ahn, Jeong Hoon Lee, Kee Don Choi, Do Hoon Kim, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung, Segyeong Joo
Summary: This study compared two diagnostic tools for non-obstructive dysphagia (NOD) and found that the volume of inverted impedance (VII) ratio is more reliable than the esophageal impedance integral (EII) ratio.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Article
Otorhinolaryngology
Jong Keun Kim, Sangpil Son, InHyuk Suh, Jin Seok Bae, Jong Youb Lim
Summary: This study investigated characteristics of dysphagia aortica (DA) by comparing videofluoroscopic swallowing study (VFSS) findings among postoperative dysphagia aortica (PDA) patients, dysphagia after brainstem infarction (DBI) patients, dysphagia after anterior cervical discectomy and fusion (DACDF) patients, and subjective swallowing difficulty (SSD) patients. The study found that PDA patients had higher FDS scores on thin liquids than SSD patients but lower than DBI patients, while their scores on thick liquids were lower than DBI or DACDF patients. Additionally, PDA patients had longer esophageal transit time compared to other groups.
Review
Audiology & Speech-Language Pathology
Erin L. Reedy, Teri Lynn Herbert, Heather Shaw Bonilha
Summary: This review explored the importance of visualizing the esophagus during modified barium swallow studies and concluded that it is a critical component for accurate diagnosis and treatment recommendations for patients with swallowing disorders.
AMERICAN JOURNAL OF SPEECH-LANGUAGE PATHOLOGY
(2021)
Article
Clinical Neurology
Stacey Sullivan, Natalie Grant, Colleen Hammond, William S. David, Florian Eichler, Reza Sadjadi
Summary: This study aims to better characterize swallowing impairments in patients with nephropathic cystinosis using MBSImP analysis, identifying oral and pharyngeal stage dysphagia as crucial to these patients.
Article
Gastroenterology & Hepatology
Jeroen M. Schuitenmaker, Froukje B. van Hoeij, Marlies P. Schijven, Jan Tack, Jose M. Conchillo, Eric J. Hazebroek, Andre J. P. M. Smout, Albert J. Bredenoord
Summary: The study results indicate that pneumatic dilation with a 35 mm balloon is not superior to sham dilation for the treatment of persistent dysphagia after fundoplication.
Review
Gastroenterology & Hepatology
Rena Yadlapati, John E. Pandolfino, Mark R. Fox, Albert J. Bredenoord, Peter J. Kahrilas
Summary: Key modifications in Chicago Classification version 4.0 (CCv4.0) include increased requirements for diagnosis of esophagogastric junction outflow obstruction, stricter criteria for the clinical relevance of manometric patterns, standardization of manometric protocol, redefinition of ineffective esophageal motility, and a shift from distinguishing major versus minor motility disorders to separation of disorders of EGJ outflow from disorders of peristalsis.
NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Article
Gastroenterology & Hepatology
Rena Yadlapati, Peter J. Kahrilas, Mark R. Fox, Albert J. Bredenoord, C. Prakash Gyawali, Sabine Roman, Arash Babaei, Ravinder K. Mittal, Nathalie Rommel, Edoardo Savarino, Daniel Sifrim, Andre Smout, Michael F. Vaezi, Frank Zerbib, Junichi Akiyama, Shobna Bhatia, Serhat Bor, Dustin A. Carlson, Joan W. Chen, Daniel Cisternas, Charles Cock, Enrique Coss-Adame, Nicola de Bortoli, Claudia Defilippi, Ronnie Fass, Uday C. Ghoshal, Sutep Gonlachanvit, Albis Hani, Geoffrey S. Hebbard, Kee Wook Jung, Philip Katz, David A. Katzka, Abraham Khan, Geoffrey Paul Kohn, Adriana Lazarescu, Johannes Lengliner, Sumeet K. Mittal, Taher Omari, Moo In Park, Roberto Penagini, Daniel Pohl, Joel E. Richter, Jordi Serra, Rami Sweis, Jan Tack, Roger P. Tatum, Radu Tutuian, Marcelo F. Vela, Reuben K. Wong, Justin C. Wu, Yinglian Xiao, John E. Pandolfino
Summary: CCv4.0 is an updated classification scheme for esophageal motility disorders using HRM, developed by fifty-two international experts in seven subgroups over two years. Key updates include a more rigorous and expansive HRM protocol, refined definition of EGJOO, stricter criteria for ineffective esophageal motility, and description of baseline EGJ metrics. These changes aim to provide more standardized criteria for disorders of peristalsis and obstruction at the EGJ.
NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Article
Gastroenterology & Hepatology
Willemijn E. de Rooij, Floor Bennebroek Evertsz', A. Lei, Albert J. Bredenoord
Summary: The research found that some adult EoE patients suffer from mental distress, with patients aged 18-35 at a 3-fold risk of significant anxiety. Population-based studies are needed and a proactive approach in screening for and treating these psychological symptoms in EoE practice is essential.
NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Article
Nutrition & Dietetics
Marlou L. A. de Kroon, Simone R. B. M. Eussen, Bridget A. Holmes, Lucien F. Harthoorn, Marijn J. Warners, Albert J. Bredenoord, Bram D. van Rhijn, Mylene van Doorn, Berber J. Vlieg-Boerstra
Summary: The study found that adult EoE patients had higher saturated fat intake and lower dietary fiber intake. EoE patients had lower overall diet quality compared to the general population.
Review
Immunology
Elizabeth A. Jacobsen, David J. Jackson, Enrico Heffler, Sameer K. Mathur, Albert J. Bredenoord, Ian D. Pavord, Praveen Akuthota, Florence Roufosse, Marc E. Rothenberg
Summary: Research on manipulating mouse and human eosinophils through experimental systems has made significant progress in revealing their roles in the immune system. Anti-eosinophil therapeutics have emerged as a new class of drugs, offering valuable insights into the consequences of eosinophil knockout in humans.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 39
(2021)
Review
Gastroenterology & Hepatology
Sara Nullens, Paul Fockens, Albert J. Bredenoord
Summary: Idiopathic achalasia is a primary motility disorder of the esophagus, leading to symptoms such as dysphagia and weight loss. There are various treatment options, with POEM and LHM showing good success rates for symptom relief, although POEM is associated with a higher risk of reflux disease and erosive esophagitis.
CURRENT OPINION IN GASTROENTEROLOGY
(2021)
Review
Gastroenterology & Hepatology
Albert J. Bredenoord, Kiran Patel, Alain M. Schoepfer, Evan S. Dellon, Mirna Chehade, Seema S. Aceves, Jonathan M. Spergel, Brad Shumel, Yamo Deniz, Paul J. Rowe, Juby A. Jacob-Nara
Summary: Eosinophilic esophagitis is a chronic inflammatory disease that has a negative impact on patients' quality of life. Current treatments do not provide long-term disease control, highlighting the need for effective long-term therapies and a better understanding of patients' perspectives.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Pharmacology & Pharmacy
Angela Y. Lam, Christopher Ma, Jeffrey K. Lee, Albert J. Bredenoord
Summary: Eosinophilic esophagitis (EoE) is an increasingly common inflammatory disorder causing esophageal symptoms, and there are currently no approved therapies. However, progress in understanding the underlying pathophysiology has led to the development of new molecular targeted treatments that may change the management of EoE in the future.
CURRENT OPINION IN PHARMACOLOGY
(2022)
Review
Gastroenterology & Hepatology
Jeroen M. Schuitenmaker, Thijs Kuipers, Andre J. P. M. Smout, Paul Fockens, Albert J. Bredenoord
Summary: For the treatment of nocturnal gastroesophageal reflux symptoms, a sequential treatment strategy involving head of bed elevation, prolonging dinner-to-bed time, promoting left lateral decubitus position, and acid-suppressive medication is recommended. Insufficient evidence currently exists for the use of nCPAP, hypnotics, baclofen, and adding bedtime H2 receptor antagonists to reduce nocturnal reflux symptoms.
NEUROGASTROENTEROLOGY AND MOTILITY
(2022)
Editorial Material
Gastroenterology & Hepatology
Albert J. Bredenoord
Article
Gastroenterology & Hepatology
Jeroen M. Schuitenmaker, Thijs Kuipers, Marlies P. Schijven, Andre J. P. M. Smout, Paul Fockens, Albert J. Bredenoord
Summary: This study evaluated the effect of an electronic positional therapy wearable device on nocturnal gastroesophageal reflux. The results showed that the device improved reflux symptoms, reduced the number of reflux episodes, and promoted left lateral decubitus sleep position, leading to improvement in reflux parameters.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Article
Gastroenterology & Hepatology
Sudharshan Achalu, Rani Berry, Justin Zhuo, Albert J. Bredenoord, John O. Clarke, Ronnie Fass, C. Prakash Gyawali, Peter J. Kahrilas, David A. Katzka, Benson T. Massey, Roberto Penagini, Sabine Roman, Edoardo Savarino, Marcelo F. Vela, Afrin N. Kamal
Summary: This study aimed to develop a dysphagia-specific question prompt list (QPL) to improve patient-physician communication. A two-round Delphi method and survey were used to generate a QPL consisting of 40 questions, incorporating both expert and patient perspectives.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Article
Gastroenterology & Hepatology
Albert J. Bredenoord, Evan Dellon, Ikuo Hirano, Alfredo J. Lucendo, Christoph Schlag, Xian Sun, Lila Glotfelty, Leda Mannent, Jennifer Maloney, Elizabeth Laws, Eric Mortensen, Arsalan Shabbir
Article
Gastroenterology & Hepatology
Guy Boeckxstaens, Stefanie Elsen, Ann Belmans, Vito Annese, Albert J. Bredenoord, Olivier R. Busch, Mario Costantini, Uberto Fumagalli, Andre J. P. M. Smout, Jan Tack, Tim Vanuytsel, Giovanni Zaninotto, Renato Salvador
Summary: The 10-year follow-up of the European Achalasia Trial comparing endoscopic pneumodilation (PD) with laparoscopic Heller myotomy (LHM) showed that both treatments are equally effective in treating achalasia, with limited risk of developing gastro-oesophageal reflux.