4.7 Editorial Material

Chaperoning ribosome assembly

Journal

JOURNAL OF CELL BIOLOGY
Volume 189, Issue 1, Pages 11-12

Publisher

ROCKEFELLER UNIV PRESS
DOI: 10.1083/jcb.201002102

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Funding

  1. Direct For Biological Sciences
  2. Div Of Molecular and Cellular Bioscience [1062243] Funding Source: National Science Foundation

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Chaperones help proteins fold in all cellular compartments, and many associate directly with ribosomes, capturing nascent chains to assist their folding and prevent aggregation. In this issue, new data from Koplin et al. (2010. J. Cell Biol. doi: 10.1083/jcb.200910074) and Albanese et al. (2010. J. Cell Biol. doi: 10.1083/jcb.201001054) suggest that in addition to promoting protein folding, the chaperones ribosome-associated complex (RAC), nascent chain-associated complex (NAC), and Jjj1 also help in the assembly of ribosomes.

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