Article
Public, Environmental & Occupational Health
Oluwatoyin Olukotun, Joni S. Williams, Zhipeng Zhou, Olaitan Akinboboye, Leonard E. Egede
Summary: This study investigated the relationship between prior incarceration and heart disease, finding a significant association between previous incarceration and heart disease, suggesting that exposure to incarceration may heighten susceptibility to heart disease. Further research is needed to elucidate the mechanisms through which incarceration impacts cardiovascular health.
Article
Clinical Neurology
Hyun-Bum Kim, Youn-Sun Park, Ju-Eun Lee, Kyung-Do Han, Young-Hak Park
Summary: Through questionnaires, it was found that self-recognition of voice disorder (SRVD) is closely related to mental health status, including psychological stress, depressive symptoms, and suicidal ideation. The study also revealed that long-term SRVD is associated with more pronounced psychological stress, depressive symptoms, and suicidal ideation. These findings highlight the significant connection between voice and emotions.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Medicine, General & Internal
Yapeng Li, Ling Yin, Ying Shen, Anran Wang, Lue Zhou, Yuan Gao, Yusheng Li, Jie Lu, Songhe Shi, Chuansheng Tian, Yuming Xu, Longde Wang
Summary: This study aims to explore the distribution differences of common risk factors between coronary heart disease (CHD) and stroke in China. The study found substantial differences in the distribution of risk factors for CHD and stroke, indicating the need for specific prevention and control measures based on these differences.
Article
Psychiatry
Angela Marotta, Antonio Lasalvia, Mirta Fiorio, Enrico Zanalda, Guido Di Sciascio, Claudia Palumbo, Davide Papola, Corrado Barbui, Michele Tinazzi
Summary: This study examines the knowledge, opinion, and clinical approach of Italian psychiatrists towards functional neurological disorder (FND). The findings suggest that Italian psychiatrists tend to view FND as psychogenetic, primarily categorized as conversion disorders with a psychological etiology. They consider psychotherapy combined with pharmacological therapy as the most appropriate treatment, while physiotherapy is under-recognized. Promoting education about novel approaches to FND is crucial for improving care for patients.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Public, Environmental & Occupational Health
Leticia Cristina Machado de Sousa, Nathalia Rabello Silva, Catarina Machado Azeredo, Ana Elisa Madalena Rinaldi, Luciana Saraiva da Silva
Summary: The aim of this study was to identify patterns related to health and their association with chronic kidney disease (CKD) in the Brazilian population. Three health-related patterns - metabolic factors, behavioral risk factors and behavioral protective factors - were identified. The pattern referring to metabolic factors was found to be significantly associated with CKD.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Environmental Sciences
Qingping Xue, An Pan, Ying Wen, Yichao Huang, Da Chen, Chun-Xia Yang, Jason H. Y. Wu, Jie Yang, Jay Pan, Xiong-Fei Pan
Summary: Chronic exposure to pyrethroids, as indicated by urinary levels of 3-phenoxybenzoic acid, was found to be significantly associated with cardiovascular disease and coronary heart disease in the US adults. However, no significant association was observed with stroke.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Immunology
Qi-Liang Zhang, Xiu-Hua Chen, Si-Jia Zhou, Yu-Qing Lei, Jiang-Shan Huang, Qiang Chen, Hua Cao
Summary: This study aimed to explore the relationship between heart failure and intestinal microbiota in infants with congenital heart disease. The results showed that infants with heart failure caused by congenital heart disease had significantly disordered composition of the intestinal microbiota, with an increase in pathogenic bacteria, a decrease in beneficial bacteria, and a decrease in diversity and richness. Retinol metabolism in the intestinal microbiota was significantly downregulated in the heart failure group. These findings highlight the association between heart failure and intestinal microbiota.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Respiratory System
Leanne M. Poulos, Rosario D. Ampon, David C. Currow, Guy B. Marks, Brett G. Toelle, Helen K. Reddel
Summary: Chronic respiratory symptoms such as breathlessness and cough can lead to significant distress and may indicate underlying health issues. A survey in Australia found that a high percentage of adults experience breathlessness, with many suffering from health burdens even without a diagnosed respiratory or heart condition. The extent of underdiagnosis of these conditions or alternative causes of breathlessness warrants further investigation.
Article
Public, Environmental & Occupational Health
Longjian Liu, Nathalie S. May, Priscila Y. Sato, Paakhi Srivastava, Leslie A. McClure
Summary: This study aimed to examine the association between pre-existing cardiovascular disorders and the risk of COVID-19 among community-dwelling adults in the United States. Data from the 2021 National Health Interview Survey were analyzed, and the results showed that both younger and older adults with pre-existing cardiovascular risk factors and diseases had a significantly higher risk of COVID-19 infection. This risk association was more substantial among minority populations.
ANNALS OF EPIDEMIOLOGY
(2023)
Article
Psychiatry
Rosa De Stefano, Clemente Cedro, Fiammetta Iannuzzo, Carmenrita Infortuna, Clara Lombardo, Gianluca Pandolfo, Maria Rosaria Anna Muscatello, Antonio Bruno
Summary: This study investigated the presence of subthreshold psychopathological symptoms and internet addiction in Italian adults from the general population, and found significant positive correlations between the two.
PSYCHIATRY RESEARCH
(2022)
Article
Multidisciplinary Sciences
Pierre Petitet, Jacqueline Scholl, Bahaaeddin Attaallah, Daniel Drew, Sanjay Manohar, Masud Husain
Summary: The study found a positive correlation between apathy and impulsivity in young adults, but the relationship is more complex when analyzed at the sub-scale level. Social apathy is negatively correlated with impulsive behavior, and emotional apathy is orthogonal to other domains.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Saif Al-Shamsi
Summary: Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of morbidity and mortality among United Arab Emirates (UAE) nationals. This study aimed to develop and validate a novel and practical 10-year ASCVD risk nomogram using risk factors known to be significant in UAE nationals, in order to improve ASCVD risk prediction in this high-risk population.
Article
Multidisciplinary Sciences
Hossein Pakdaman, Ali Amini Harandi, Koroush Gharagozli, Farshid Alaeddini, Akram Esfandani, Seyed Hamidreza Mirbehbahani, Taher Doroudi, Pirhossein Kolivand, Parviz Bahrami, Hadi Kazemi
Summary: Epilepsy is receiving increased public health attention globally, with research in Iran suggesting a higher lifetime prevalence compared to the worldwide average. The study identified focal and generalized epilepsy as the main types, with a slightly higher proportion of male patients. This two-phase door-to-door survey method was utilized for data collection.
SCIENTIFIC REPORTS
(2021)
Article
Public, Environmental & Occupational Health
Mark A. Bellis, Catherine A. Sharp, Karen Hughes, Alisha R. Davies
Summary: The study explores patterns of online activity predictive of Digital Overuse and Addictive Traits (DOAT) and the associations between DOAT and mental well-being. Results show that individuals with higher DOAT may experience improvements or worsening in self-esteem and other measures of mental well-being when using the internet for health purposes. Efforts to understand risk factors for digital overuse and its impacts on well-being are crucial for successful digital revolution.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Emergency Medicine
Seong Jun Ahn, Yong Hwan Kim, Jun Ho Lee, Dong Woo Lee, Seong Youn Hwang, Byung Kook Lee, In Soo Cho, Sang Hoon Oh, Kyoung-Chul Cha
Summary: This study evaluated the relationship between cooling time and neurological outcomes in out-of-hospital cardiac arrest patients. The results showed that there was no significant correlation between cooling time and neurological outcomes at 6 months.
ACADEMIC EMERGENCY MEDICINE
(2022)
Article
Medicine, General & Internal
Lisa K. Kuramoto, Boris G. Sobolev, Penelope M. A. Brasher, Michael W. Tang, Jacquelyn J. Cragg
Article
Clinical Neurology
Matthew C. Dorton, V-E M. Lucci, Sonja de Groot, Thomas M. Loughin, Jacquelyn J. Cragg, John K. Kramer, Marcel W. M. Post, Victoria E. Claydon
Summary: This multicentre, cross-sectional study in the Netherlands aimed to identify markers of obesity, injury characteristics, and autonomic function variables associated with cardiovascular disease (CVD) risk in individuals with spinal cord injury (SCI). Results showed that waist circumference, duration of injury, systolic arterial pressure, peak heart rate, among other factors, were important predictive variables for 10-year CVD risk in SCI patients.
Article
Pharmacology & Pharmacy
Jacquelyn J. Cragg, Laurent Azoulay, Gary Collins, Mary A. De Vera, Mahyar Etminan, Fawziah Lalji, Andrea S. Gershon, Gordon Guyatt, Mark Harrison, Catherine Jutzeler, Rosemin Kassam, Tetyana Kendzerska, Larry Lynd, Mohammad Ali Mansournia, Mohsen Sadatsafavi, Bobo Tong, Freda M. Warner, Helen Tremlett
Summary: The use of observational data is crucial for assessing drug effectiveness and safety, and transparent, consistent, and accurate reporting of these studies is essential. Recommendations to extend existing reporting guidelines include explicit checklist items on study registration, causal diagrams, and bias assessment.
EXPERT OPINION ON DRUG SAFETY
(2021)
Review
Biochemistry & Molecular Biology
Sina Marzoughi, Ankur Banerjee, Catherine R. Jutzeler, Marco A. M. Prado, Jan Rosner, Jacquelyn J. Cragg, Neil Cashman
Summary: The cholinergic system is a complex neurotransmitter system involved at multiple levels of the nervous system. Anticholinergic medications, commonly prescribed, have been linked to dementia and may impact cerebral vasculature and neuroinflammation, potentially contributing to progression of neurodegenerative diseases. Long-term use of these medications has detrimental effects beyond short-term cognitive impairment, affecting cholinergic neurotransmission and receptors on immune cells and vasculature.
JOURNAL OF NEUROCHEMISTRY
(2021)
Review
Critical Care Medicine
Paul Aspinall, Liam Harrison, Paulina Scheuren, Jacquelyn J. Cragg, Adam R. Ferguson, James D. Guest, Jane Hsieh, Linda Jones, Steven Kirshblum, Dan Lammertse, Brian K. Kwon, John L. K. Kramer
Summary: This study assessed the reporting satisfaction of safety information in past clinical trials on spinal cord injury, revealing that only 30% of trials had satisfactory reporting on clinical adverse events. The majority of trials were deemed unsatisfactory in reporting laboratory-defined toxicity.
JOURNAL OF NEUROTRAUMA
(2021)
Article
Clinical Neurology
Dayton J. Kelly, Dylan Thibault, Derrick Tam, Lisa J. W. Liu, Jacquelyn J. Cragg, Allison W. Willis, James A. G. Crispo
Summary: This study identified various sociodemographic and clinical factors associated with nonelective readmission following hospitalization for traumatic brain injury (TBI), including age, history of falls, intentional self-injury, as well as previous motor vehicle or cycling accidents. Female patients were found to be less likely to be readmitted.
JOURNAL OF HEAD TRAUMA REHABILITATION
(2022)
Review
Public, Environmental & Occupational Health
Lisa K. Kuramoto, Boris G. Sobolev, Jan Rosner, Penelope M. A. Brasher, Laurent Azoulay, Jacquelyn J. Cragg
Summary: In drug safety and effectiveness studies based on secondary data, developing appropriate exposure measures is crucial. This study proposes a systematic approach linking exposure specifications to major concepts to guide the choice of exposure measure. This approach can be valuable for students and researchers in pharmacoepidemiology.
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
(2022)
Review
Anesthesiology
Rachel H. McGregor, Freda M. Warner, Lukas D. Linde, Jacquelyn J. Cragg, Jill A. Osborn, Vishal P. Varshney, Stephan K. W. Schwarz, John L. K. Kramer
Summary: This study examined the quality of meta-analyses on non-opioid pharmacological interventions for chronic postsurgical pain and found that the majority of them were of low quality, lacking analysis of publication bias. Quality improved over time and was associated with journal impact factor.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2022)
Article
Rehabilitation
James A. G. Crispo, Lisa J. W. Liu, Vanessa K. Noonan, Nancy P. Thorogood, Brian K. Kwon, Marcel F. Dvorak, Dylan Thibault, Allison Willis, Jacquelyn J. Cragg
Summary: This study examined tSCI hospitalizations among children in the United States and found that older, male, and Black children were disproportionately affected by tSCI. Hospitalizations involving Black children were more likely to be caused by firearm incidents or assault compared to hospitalizations of White children.
TOPICS IN SPINAL CORD INJURY REHABILITATION
(2022)
Review
Clinical Neurology
Carl M. Zipser, Jacquelyn J. Cragg, James D. Guest, Michael G. Fehlings, Catherine R. Jutzeler, Aileen J. Anderson, Armin Curt
Summary: Spinal cord injury is a debilitating condition that leads to impaired mobility, pain, and autonomic dysfunction. Cell-based and stem-cell-based therapies have shown promise in promoting functional recovery, but clinical trials have not yet provided reproducible evidence of their efficacy. However, recent trials have demonstrated the feasibility and long-term safety of cell transplantation into the injured spinal cord.
Article
Clinical Neurology
Rafael D. Sanguinetti, Jan Elaine Soriano, Jordan W. Squair, Jacquelyn J. Cragg, Kelly A. Larkin-Kaiser, Alexander McGirr, Aaron A. Phillips
Summary: The study aims to quantify and compare mental health and suicidal thoughts in people with and without spinal cord injury (SCI), and examine the associations between mental health, suicidal thoughts, sex, age, lifestyle, and socioeconomic factors. The results show that people with SCI have higher odds of mental health disorders and suicidal thoughts, as well as poorer self-perceived mental health and satisfaction with life. Lower household income, unhealthy lifestyle behaviors, and increased smoking use are associated with poorer mental health in individuals with SCI.
Article
Multidisciplinary Sciences
Jan Elaine Soriano, Jordan W. Squair, Jacquelyn J. Cragg, Jennifer Thompson, Rafael Sanguinetti, Bita Vaseghi, Carolyn A. Emery, Christopher Grant, Rebecca Charbonneau, Kelly A. Larkin-Kaiser, Aaron A. Phillips, Zeljko Dujic
Summary: This study found that individuals with spinal cord injury have lower levels of physical activity compared to the general population. This knowledge is important for directing future research and allocating healthcare resources.
SCIENTIFIC REPORTS
(2022)
Article
Allergy
Tae Yoon Lee, John Petkau, Nevrose Mangat, Abdollah Safari, Jacquelyn J. Cragg, Larry D. Lynd, J. Mark FitzGerald, Stuart E. Turvey, Mohsen Sadatsafavi
Summary: The study found a significant decline in pediatric asthma hospitalization rates in Canada from 2002 to 2017, but adult asthma hospitalization rates have stabilized. Since 2010, there has been a slowdown in the decrease of pediatric asthma hospitalization rates, while for adults, this slowdown started in 2008.
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
(2022)
Article
Medicine, General & Internal
Lucie Bourguignon, Bobo Tong, Fred Geisler, Martin Schubert, Frank Rohrich, Marion Saur, Norbert Weidner, Rudiger Rupp, Yorck-Bernhard B. Kalke, Rainer Abel, Doris Maier, Lukas Grassner, Harvinder S. Chhabra, Thomas Liebscher, Jacquelyn J. Cragg, John Kramer, Armin Curt, Catherine R. Jutzeler
Summary: Despite changes in the epidemiological characteristics of traumatic spinal cord injury, neurological and functional recovery has remained stable over the last two decades. This study provides an important resource for informing clinical practice and implementing new clinical trials.
Article
Medicine, General & Internal
Lisa J. W. Liu, James A. G. Crispo, Paxton Bach, Dominique R. Ansell, Dylan Thibault, Allison W. Willis, Jacquelyn J. Cragg
Summary: The objective of this study was to examine trends in amphetamine-related hospitalisations in the USA between 2003 and 2014, including by age and sex. The study found that the hospitalisation rates increased during this period, with higher rates among younger individuals and men. Regional differences were observed, with Western hospitals having higher mortality rates and shorter lengths of stay compared to Northeast hospitals. Males and self-pay patients were more likely to leave against medical advice. The study suggests that the increasing rates of amphetamine-related hospitalisation may be overshadowed by other public health crises, and regional interventions may have the greatest population health benefits.
