Article
Multidisciplinary Sciences
Kei Ichikawa, Yoshiki Tanaka, Seiji Tokiwa, Airi Naito, Yuji Hidaka, Reiko Ichikawa, Kazuo Ichikawa, Naoki Yamamoto
Summary: This study evaluated the risk of anterior capsule rupture with different phacoemulsification tips under different conditions. The results suggest that the new polymer overmolded phaco tip may reduce the risk of capsule rupture and provide useful information for improving surgical safety.
Article
Medicine, General & Internal
Hui Wang, Xuhui Liu, Xiaofeng Hu, Hua Xin, Han Bao, Shuo Yang
Summary: This study evaluated the changes in fundus vascular density and micromorphological structure in different stages of diabetic retinopathy (DR), as well as the correlation between fundus blood flow and DR severity. Patients with diabetes mellitus (DM) showed significant correlations between the densities and perfusion of retinal capillary plexuses and the severity of DR. OCTA parameters have high sensitivity and specificity in distinguishing DR from healthy eyes.
FRONTIERS IN MEDICINE
(2023)
Article
Ophthalmology
Yuyan Wang, Wei Wang, Yanan Zhu, Jia Xu, Chenqi Luo, Ke Yao
Summary: This study compared the anterior capsule contraction of hydrophilic and hydrophobic acrylic intraocular lenses (IOLs) under the same size capsulotomy with femtosecond laser-assisted cataract surgery (FLACS). The results showed that the postoperative anterior capsule contraction induced by hydrophobic IOLs was less than that induced by hydrophilic IOLs. Among the four IOLs, the capsule contraction was largest in MI60, followed by 509M, and least in iSert250 and ZCB00.
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY
(2022)
Review
Ophthalmology
Lu Chen, Yueyang Zhong, Ke Yao, Qiuli Fu
Summary: This study compared anterior capsule contraction (ACC) after cataract surgery with different materials and designs of intraocular lens (IOLs) and found that hydrophilic IOLs induced greater ACC than hydrophobic IOLs. Haptic design may also affect the degree of ACC.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Minjie Zhao, Shuzhi Zhao, Min Tang, Tao Sun, Zhi Zheng, Mingming Ma
Summary: This study found that increased AQP1 in AH may be a biomarker for cataracts in patients without diabetes and retinal glial cell activation in diabetic patients without cataracts. Additionally, levels of AQP4, Kir4.1, and GFAP in AH indicated the impact of DR progression on retinal glial cell activation.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)
Article
Computer Science, Artificial Intelligence
G. Kalyani, B. Janakiramaiah, A. Karuna, L. V. Narasimha Prasad
Summary: An improved capsule network is developed for the detection and classification of diabetic retinopathy, achieving high accuracy on different stages of fundus images through feature extraction and probability estimation.
COMPLEX & INTELLIGENT SYSTEMS
(2023)
Article
Ophthalmology
Xintong Fan, Jiajian Wang, Qilian Sheng, Ruyi Zhai, Xiangmei Kong
Summary: This study compared the long-term efficacy and safety of three surgical procedures in patients with nanophthalmos and angle-closure glaucoma. The results showed that triple procedure surgery (TS) had better postoperative intraocular pressure outcomes, lower complication rates, and lower second surgery rates compared to double procedure surgery (DS) and filtering surgery (FS).
Review
Pharmacology & Pharmacy
Rafael Simo, Olga Simo-Servat, Patricia Bogdanov, Cristina Hernandez
Summary: The concept of diabetic retinopathy has evolved to consider neurovascular unit impairment as a main target for therapeutic strategies. While neurodegeneration may not always be the primary event in the progression of the disease, phenotyping to identify patients who could benefit from neuroprotective treatments is recommended. Recent research has tested numerous neuroprotective treatments, including drugs with dual activity, aiming to address the complex nature of diabetic retinopathy.
Article
Medicine, General & Internal
Guanrong Wu, Baoyi Liu, Qiaowei Wu, Changting Tang, Zijing Du, Ying Fang, Yijun Hu, Honghua Yu
Summary: The study found that the expression of various angiogenesis and inflammation mediators in the vitreous fluid of eyes with proliferative diabetic retinopathy (PDR) was significantly increased, and there were correlations between these mediators. The levels of these mediators were also correlated with kidney damage, indicating potential common pathways in diabetic retinopathy and nephropathy.
FRONTIERS IN MEDICINE
(2021)
Article
Ophthalmology
Aniruddha Banerjee, Karthika Pandurangan, Amose Joe, Ramya Sachidanandam, Parveen Sen
Summary: The study aimed to evaluate changes in PhNR in diabetic patients with different stages of DR compared to controls. It was found that ERG amplitudes, especially B/Y PhNR, were significantly reduced even in eyes with no DR, and decreased with increasing severity of DR.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Health Care Sciences & Services
Santosh Gopi Krishna Gadde, Arpita Kshirsagar, Neha Anegondi, Thirumalesh B. Mochi, Stephane Heymans, Arkasubhra Ghosh, Abhijit Sinha Roy
Summary: The study showed that as the severity of diabetic retinopathy increases, the volume of macular edema also increases, with proliferative DR having the largest edema volume. For intravitreal injection treatment, recurrent eyes had the largest edema volume, while the treatment naive group had the smallest.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Ophthalmology
Ram Prasad, Bright Asare-Bediko, Angela Harbour, Jason L. Floyd, Dibyendu Chakraborty, Yaqian Duan, Regina Lamendella, Justin Wright, Maria B. Grant
Summary: This study suggests that the gut and plasma microbiota can transfer microbes to the retina in type 1 diabetic mice with retinopathy, which may contribute to the development of retinal inflammation and barrier dysfunction.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)
Article
Pharmacology & Pharmacy
Gianpaolo Zerbini, Silvia Maestroni, Letizia Leocani, Andrea Mosca, Michela Godi, Renata Paleari, Arianna Belvedere, Daniela Gabellini, Paola Tirassa, Valerio Castoldi, Ilaria Vigano, Silvia Galbiati, Valentina Turco, Alessandro Lambiase, Paolo Rama
Summary: This study aims to prevent diabetic retinopathy (DR) by using topical nerve growth factor (NGF). The results show that providing early neuroprotective approach can successfully prevent retinal neurodegeneration and subsequent vascular dysfunction.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Medicine, General & Internal
Jee Taek Kim, In Gul Lee
Summary: The study assessed the correlation of renal profiles with choroidal vasculature in eyes with diabetic retinopathy. The findings suggest that in patients with treatment-naive DR, choroidal vascularity index (CVI) is negatively correlated with age and serum levels of phosphorus, and positively correlated with subfoveal choroidal thickness.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Computer Science, Interdisciplinary Applications
Yogesh Kumar, Surbhi Gupta
Summary: Artificial intelligence has made significant advancements in healthcare, particularly in the field of ophthalmology. Through deep learning and transfer learning methods, AI is able to predict and identify various eye diseases, improving clinical decision-making and enhancing patient care.
ARCHIVES OF COMPUTATIONAL METHODS IN ENGINEERING
(2023)