4.3 Article

Clinical outcomes of cataract surgery after bag-in-the-lens intraocular lens implantation following ISO standard 11979-7:2006

Journal

JOURNAL OF CATARACT AND REFRACTIVE SURGERY
Volume 37, Issue 12, Pages 2120-2129

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.jcrs.2011.06.025

Keywords

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Funding

  1. U.S. Patent [6 027 531]
  2. EU [009406794.PCT/120268]

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PURPOSE: To assess the clinical outcomes of bag-in-the-lens intraocular lens (BIL IOL) implantation following the International Organization for Standardization (ISO) 11979-7:2006 in pediatric eyes and eyes with ocular comorbidities. SETTING: Antwerp University Hospital, Department of Ophthalmology, Antwerp, Belgium. DESIGN: Cohort study. METHODS: This cohort included the first series of patients having IOL implantation using the bag-in-the-lens technique. Surgeries were performed between December 1999 and September 2006. In addition to IOL implantation, the technique comprised creation of a primary posterior continuous curvilinear capsulorhexis (PCCC) equal in size to the anterior capsulorhexis. RESULTS: The study enrolled 807 eyes of 547 patients; 326 of the eyes (40.40%) had ocular comorbidity. In the 481 eyes without ocular comorbidity, the mean decimal corrected distance visual acuity was 0.52 +/- 0.24 (SD) (0.276 +/- 0.206 logMAR) preoperatively and 0.94 +/- 0.18 (-0.012 +/- 0.053 logMAR) postoperatively. The mean postoperative achieved spherical equivalent was 0.48 +/- 0.83 diopter (D) and the mean targeted refraction, -0.24 +/- 0.71 D. The A-constant was modified from 118.4 to 118.04. Posterior capsule opacification (PCO) did not occur in any adult eye during the follow-up. Retinal detachment after IOL implantation occurred in 10 eyes (1.24%). In 19 eyes, the iris was captured by the IOL haptics postoperatively. Hypopyon occurred in 3 patients and toxic anterior segment syndrome in 1 patient. CONCLUSION: The BIL IOL met the ISO criteria; that is, primary PCCC was safe in healthy eyes and in eyes with ocular comorbidities and no eye developed PCO over a mean follow-up of 26.1 +/- 21.3 months.

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