Review Article: Combination of Clopidogrel and Proton Pump Inhibitors: Implications for Clinicians

Comparison of ticagrelor, the first reversible oral P2Y12 receptor antagonist, with clopidogrel in patients with acute coronary syndromes: Rationale, design, and baseline characteristics of the PLATelet inhibition and patient Outcomes (PLATO) trial

(2009) Stefan James et al.   AMERICAN HEART JOURNAL

A population-based study of the drug interaction between proton pump inhibitors and clopidogrel

(2009) D. N. Juurlink et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Drug Interaction Between Clopidogrel and Proton Pump Inhibitors

(2009) Saira Chand Khalique et al.   Cardiology in Review

Cytochrome P450 Genetic Polymorphisms and the Response to Prasugrel

(2009) Jessica L. Mega et al.   CIRCULATION

Proton Pump Inhibitors

(2009) Kwong Ming Fock et al.   CLINICAL PHARMACOKINETICS

Identification of the Human Cytochrome P450 Enzymes Involved in the Two Oxidative Steps in the Bioactivation of Clopidogrel to Its Pharmacologically Active Metabolite

(2009) M. Kazui et al.   DRUG METABOLISM AND DISPOSITION

Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with coronary artery disease

(2009) C. Varenhorst et al.   EUROPEAN HEART JOURNAL

Risk of Adverse Outcomes Associated With Concomitant Use of Clopidogrel and Proton Pump Inhibitors Following Acute Coronary Syndrome

(2009) P. Michael Ho   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Comparison of Omeprazole and Pantoprazole Influence on a High 150-mg Clopidogrel Maintenance Dose

(2009) Thomas Cuisset et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The CYP2C19*17 allele is associated with better platelet response to clopidogrel in patients admitted for non-ST acute coronary syndrome

(2009) C. FRÉRE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Famotidine for the prevention of peptic ulcers and oesophagitis in patients taking low-dose aspirin (FAMOUS): a phase III, randomised, double-blind, placebo-controlled trial

(2009) Ali S Taha et al.   LANCET

Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials

(2009) Michelle L O'Donoghue et al.   LANCET

Gastrointestinal Bleeding in Patients Receiving a Combination of Aspirin, Clopidogrel, and Enoxaparin in Acute Coronary Syndrome

(2008) Fook-Hong Ng et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The Biotransformation of Prasugrel, a New Thienopyridine Prodrug, by the Human Carboxylesterases 1 and 2

(2008) E. T. Williams et al.   DRUG METABOLISM AND DISPOSITION

Effects of the Proton Pump Inhibitor Lansoprazole on the Pharmacokinetics and Pharmacodynamics of Prasugrel and Clopidogrel

(2008) David S. Small et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Influence of Omeprazole on the Antiplatelet Action of Clopidogrel Associated With Aspirin

(2008) Martine Gilard et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The Association of Cigarette Smoking With Enhanced Platelet Inhibition by Clopidogrel

(2008) Kevin P. Bliden et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

ACCF/ACG/AHA 2008 Expert Consensus Document on Reducing the Gastrointestinal Risks of Antiplatelet Therapy and NSAID Use

(2008) Deepak L. Bhatt et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The common gene variants of CYP2C19 affect pharmacokinetics and pharmacodynamics in an active metabolite of clopidogrel in healthy subjects

(2008) K. UMEMURA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Cytochrome P-450 Polymorphisms and Response to Clopidogrel

(2008) Jessica L. Mega et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetic Determinants of Response to Clopidogrel and Cardiovascular Events

(2008) Tabassome Simon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cytochrome P450 and Chemical Toxicology

(2007) F. Peter Guengerich   CHEMICAL RESEARCH IN TOXICOLOGY