New Advances in the Genetic Basis of Atrial Fibrillation

Meta-analysis identifies six new susceptibility loci for atrial fibrillation

(2012) Patrick T Ellinor et al.   NATURE GENETICS

PITX2c Is Expressed in the Adult Left Atrium, and Reducing Pitx2c Expression Promotes Atrial Fibrillation Inducibility and Complex Changes in Gene Expression

(2011) Paulus Kirchhof et al.   Circulation-Cardiovascular Genetics

PITX2 Insufficiency Leads to Atrial Electrical and Structural Remodeling Linked to Arrhythmogenesis

(2011) Ana Chinchilla et al.   Circulation-Cardiovascular Genetics

HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the Channelopathies and Cardiomyopathies

(2011) Michael J. Ackerman et al.   HEART RHYTHM

The Duration of Pacing-induced Atrial Fibrillation Is Reduced in Vivo by Inhibition of Small Conductance Ca2+-activated K+ Channels

(2011) Lasse Skibsbye et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Monogenic atrial fibrillation as pathophysiological paradigms

(2010) S. Mahida et al.   CARDIOVASCULAR RESEARCH

Independent Susceptibility Markers for Atrial Fibrillation on Chromosome 4q25

(2010) Steven A. Lubitz et al.   CIRCULATION

European Ancestry as a Risk Factor for Atrial Fibrillation in African Americans

(2010) Gregory M. Marcus et al.   CIRCULATION

Inhibition of Small-Conductance Ca 2+ -Activated K + Channels Terminates and Protects Against Atrial Fibrillation

(2010) Jonas Goldin Diness et al.   Circulation-Arrhythmia and Electrophysiology

Risk prediction using genome-wide association studies

(2010) Charles Kooperberg et al.   GENETIC EPIDEMIOLOGY

Association Between Familial Atrial Fibrillation and Risk of New-Onset Atrial Fibrillation

(2010) Steven A. Lubitz et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function

(2010) A. Beqqali et al.   JOURNAL OF CELL SCIENCE

Assessment of Conventional Cardiovascular Risk Factors and Multiple Biomarkers for the Prediction of Incident Heart Failure and Atrial Fibrillation

(2010) J. Gustav Smith et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Chromosome 4q25 Variants and Atrial Fibrillation Recurrence After Catheter Ablation

(2010) Daniela Husser et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Common variants in KCNN3 are associated with lone atrial fibrillation

(2010) Patrick T Ellinor et al.   NATURE GENETICS

Genome-wide association studies in diverse populations

(2010) Noah A. Rosenberg et al.   NATURE REVIEWS GENETICS

Uncovering the roles of rare variants in common disease through whole-genome sequencing

(2010) Elizabeth T. Cirulli et al.   NATURE REVIEWS GENETICS

Pitx2 prevents susceptibility to atrial arrhythmias by inhibiting left-sided pacemaker specification

(2010) J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Significance Levels and Weighted Hypothesis Testing

(2010) Kathryn Roeder et al.   STATISTICAL SCIENCE

Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS

(2010) Dan L. Nicolae et al.   PLoS Genetics

Hypothesis-Driven Candidate Gene Association Studies: Practical Design and Analytical Considerations

(2009) T. J. Jorgensen et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Mutations in Sodium Channel β1- and β2-Subunits Associated With Atrial Fibrillation

(2009) Hiroshi Watanabe et al.   Circulation-Arrhythmia and Electrophysiology

Variation in the 4q25 Chromosomal Locus Predicts Atrial Fibrillation After Coronary Artery Bypass Graft Surgery

(2009) Simon C. Body et al.   Circulation-Cardiovascular Genetics

Mutation in the S3 segment of KCNQ1 results in familial lone atrial fibrillation

(2009) Saumya Das et al.   HEART RHYTHM

Assessment of association of rs2200733 on chromosome 4q25 with atrial fibrillation and ischemic stroke in a Chinese Han population

(2009) Lisong Shi et al.   HUMAN GENETICS

Ablation of a Ca2+-activated K+channel (SK2 channel) results in action potential prolongation in atrial myocytes and atrial fibrillation

(2009) Ning Li et al.   JOURNAL OF PHYSIOLOGY-LONDON

Development of a risk score for atrial fibrillation (Framingham Heart Study): a community-based cohort study

(2009) Renate B Schnabel et al.   LANCET

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke

(2009) Daniel F Gudbjartsson et al.   NATURE GENETICS

Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry

(2009) Emelia J Benjamin et al.   NATURE GENETICS

Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke

(2008) Solveig Gretarsdottir et al.   ANNALS OF NEUROLOGY

Association of rs2200733 at 4q25 with atrial flutter/fibrillation diseases in an Italian population

(2008) C Viviani Anselmi et al.   HEART