Article
Cardiac & Cardiovascular Systems
Lucas Yixi Xing, Soren Zoga Diederichsen, Soren Hojberg, Derk W. Krieger, Claus Graff, Ruth Frikke-Schmidt, Morten S. Olesen, Axel Brandes, Lars Kober, Ketil Jorgen Haugan, Jesper Hastrup Svendsen
Summary: This study aimed to investigate the potential of NT-proBNP as a marker for AF screening efficacy and stroke prevention. The results showed that in individuals over 70 years old with additional stroke risk factors, ILR screening was associated with a significant reduction in stroke risk among those with higher NT-proBNP levels.
Article
Cardiac & Cardiovascular Systems
Yaqiong Wang, Xuesen Cao, Jinbo Yu, Yongmei Zhang, Xianzhe Li, Xiaohong Chen, Jianzhou Zou, Bo Shen, Xiaoqiang Ding
Summary: NT-pro BNP level is independently correlated with volume overload in hemodialysis patients, even in those with reduced left ventricular ejection function. NT-pro BNP can be a predictive factor for volume overload in these patients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Medicine, General & Internal
Pang-Yen Liu, Chin Lin, Chin-Sheng Lin, Wen-Hui Fang, Chia-Cheng Lee, Chih-Hung Wang, Dung-Jang Tsai
Summary: The study aimed to develop an AI-ECG system to predict BNP/pBNP values in patients with cardiovascular diseases (CVDs) and compare their values for future mortality. The results showed that the AI-ECG accurately predicted BNP/pBNP values, and pBNP was a better predictor of future mortality.
Article
Anesthesiology
Chunrong Wang, Yuchen Gao, Yu Tian, Yuefu Wang, Wei Zhao, Daniel Sessler, Yuan Jia, Bingyang Ji, Xiaolin Diao, Xinyi Xu, Jianhui Wang, Jun Li, Sudena Wang, Jia Liu
Summary: Preoperative NT-proBNP concentration is associated with postoperative AKI after major cardiac surgery, and including NT-proBNP substantially improves AKI predictions based on other preoperative factors.
BRITISH JOURNAL OF ANAESTHESIA
(2021)
Article
Rheumatology
Karim Sacre, Evelyne Vinet, Christian A. Pineau, Arielle Mendel, Fares Kalache, Louis-Pierre Grenier, Thao Huynh, Sasha Bernatsky
Summary: NT-proBNP is associated with cardiovascular damage in SLE patients and could serve as a biomarker for cardiovascular damage. NT-proBNP levels are associated with hypertension, dyslipidemia, age, smoking history, reduced eGFR, prior pericarditis/pleuritis, and aPL antibodies.
Article
Cardiac & Cardiovascular Systems
Hsin-Chia Lin, Shu-Chien Huang, Mei-Hwan Wu, Jou-Kou Wang, Ming-Tai Lin, Chun-An Chen, Chun-Wei Lu, Yih-Sharng Chen, Shuenn-Nan Chiu
Summary: The role of preoperative N-terminal pro-brain natriuretic peptide level in patient outcomes after the Fontan operation was investigated in this study. The results showed that high preoperative N-terminal pro-brain natriuretic peptide was associated with poor outcomes after the operation.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Article
Pediatrics
Agnes-Sophie Fritz, Titus Keller, Angela Kribs, Christoph Huenseler
Summary: This observational study provides reference values for NT-proBNP levels of very and extremely preterm infants during their first weeks of life. NT-proBNP values during the first week of life in premature infants without complications depend on gestational age at birth.
EUROPEAN JOURNAL OF PEDIATRICS
(2021)
Article
Medicine, General & Internal
Jose Tunon, Ana Pello, Alvaro Acena, Sergio Ramos-Cillan, Juan Martinez-Milla, Oscar Gonzalez-Lorenzo, Jesus Fuentes-Antras, Nieves Tarin, Carmen Cristobal, Luis M. Blanco-Colio, Jose Luis Martin-Ventura, Ana Huelmos, Carlos Gutierrez-Landaluce, Marta Lopez-Castillo, Joaquin Alonso, Lorenzo Lopez Bescos, Jesus Egido, Ignacio Mahillo-Fernandez, Oscar Lorenzo
Summary: In patients with coronary artery disease, NT-proBNP was an independent predictor of receiving a cancer diagnosis in the first three years of follow-up, but not later, suggesting that it could be detecting subclinical undiagnosed cancers.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
James L. Januzzi, Xi Tan, Lingfeng Yang, Joanne E. Brady, Mei Yang, Puja Banka, Dominik Lautsch
Summary: The study found that NT-proBNP testing was not frequently performed in patients with heart failure with reduced ejection fraction (HFrEF) in US clinical practice, and the concentrations varied across different data sources and subgroups within HFrEF.
Review
Immunology
Victor Zhu, Luke A. Perry, Mark Plummer, Reny Segal, Julian Smith, Zhengyang Liu
Summary: This study aimed to evaluate the effectiveness of BNP and NT-proBNP in predicting adverse recipient outcomes after cardiac transplantation. The results showed that serum BNP and NT-proBNP cannot reliably predict adverse outcomes following cardiac transplantation.
TRANSPLANTATION REVIEWS
(2023)
Article
Cardiac & Cardiovascular Systems
Charlotte Van Edom, Steven Jacobs, Libera Fresiello, Katrien Vandersmissen, Christophe Vandenbriele, Walter Droogne, Bart Meyns
Summary: The study found a decrease in NT-proBNP levels and improvement in submaximal and maximal exercise capacity in LVAD recipients. There was also an inverse correlation between NT-proBNP levels and exercise test results.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Article
Urology & Nephrology
Takaya Sasaki, Emi Oishi, Takuya Nagata, Satoko Sakata, Sanmei Chen, Yoshihiko Furuta, Takanori Honda, Daigo Yoshida, Jun Hata, Nobuo Tsuboi, Takanari Kitazono, Takashi Yokoo, Toshiharu Ninomiya
Summary: The study found that higher serum NT-proBNP levels were associated with increased risks of developing chronic kidney disease (CKD) and a more rapid decline in estimated glomerular filtration rate (eGFR). In the general Japanese population, serum NT-proBNP could serve as a useful biomarker for assessing the future risk of CKD.
KIDNEY INTERNATIONAL REPORTS
(2021)
Article
Cardiac & Cardiovascular Systems
James L. Januzzi, Javed Butler, Faiez Zannad, Gerasimos Filippatos, Joao Pedro Ferreira, Stuart J. Pocock, Naveed Sattar, Subodh Verma, Ola Vedin, Tomoko Iwata, Martina Brueckmann, Milton Packer, Stefan D. Anker
Summary: In this study, the associations between NT-proBNP and hscTnT biomarkers and clinical outcomes in heart failure patients were evaluated. Higher baseline NT-proBNP and hs-cTnT concentrations were associated with more comorbidities and worse heart failure severity. Empagliflozin treatment consistently reduced the risk for cardiovascular events and reduced the decline of eGFR across different levels of NT-proBNP and hs-cTnT. Furthermore, empagliflozin modestly lowered NT-proBNP levels.
JACC-HEART FAILURE
(2022)
Review
Cardiac & Cardiovascular Systems
Pamela Nogueira Cavalcante, Gabriel Kanhouche, Vitor Emer Egypto Rosa, Carlos M. Campos, Mariana Pezzute Lopes, Maria Antonieta Albanez A. de M. Lopes, Roney Orismar Sampaio, Fabio Sandoli de Brito Jr, Flavio Tarasoutchi, Alexandre Antonio Cunha Abizaid
Summary: B-type natriuretic peptide (BNP) and N-terminal pro-BNP (NT-pro BNP) are cardiac biomarkers released in response to increased ventricular and atrial wall stress. Studies have shown that elevated levels of these biomarkers are correlated with the severity of aortic stenosis (AS) and can predict the need for intervention. They play a crucial role in risk stratification and predicting cardiovascular outcomes of patients with severe AS. This paper aims to summarize the evidence of the role of BNP and NT-pro BNP in AS, before and after intervention.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Enrique Castro-Portillo, Raul Lopez-Izquierdo, Ancor Sanz-Garcia, Guillermo J. Ortega, Juan F. Delgado-Benito, Miguel A. Castro Villamor, Irene Sanchez-Soberon, Carlos Del Pozo Vegas, Francisco Martin-Rodriguez
Summary: This study demonstrates that POCT NT-proBNP is a strong predictor of early mortality in ACVD, showing excellent predictive capacity in cases of syncope, but it does not have the ability to predict outcomes in patients with acute heart failure.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)