Folic Acid Supplementation Ameliorates Oxidative Stress, Metabolic Functions and Developmental Anomalies in a Novel Fly Model of Parkinson’s Disease

Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson’s disease

(2014) Roberta Tufi et al.   NATURE CELL BIOLOGY

Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases

(2013) B.E. Riley et al.   Nature Communications

Animal models of Parkinson’s disease

(2012) Fabio Blandini et al.   FEBS Journal

Drosophila Nociceptors Mediate Larval Aversion to Dry Surface Environments Utilizing Both the Painless TRP Channel and the DEG/ENaC Subunit, PPK1

(2012) Wayne A. Johnson et al.   PLoS One

Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells

(2011) Kye-Young Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

The parkin Mutant Phenotype in the Fly Is Largely Rescued by Metal-Responsive Transcription Factor (MTF-1)

(2011) N. Saini et al.   MOLECULAR AND CELLULAR BIOLOGY

Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect

(2011) C. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apoptosis in Parkinson's disease: Is p53 the missing link between genetic and sporadic Parkinsonism?

(2010) Cristine Alves da Costa et al.   CELLULAR SIGNALLING

Parkin Suppresses c-Jun N-terminal kinase-induced cell death via transriptional regulation in Drosophila

(2010) Soojin Hwang et al.   MOLECULES AND CELLS

Extended lifespan of Drosophila parkin mutants through sequestration of redox-active metals and enhancement of anti-oxidative pathways

(2010) Nidhi Saini et al.   NEUROBIOLOGY OF DISEASE

Evidence that folic acid deficiency is a major determinant of hyperhomocysteinemia in Parkinson´s disease

(2009) Eliseu Felippe dos Santos et al.   METABOLIC BRAIN DISEASE

Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease

(2009) Cristine Alves da Costa et al.   NATURE CELL BIOLOGY

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY