Synthesis ofN-acetyl Glucosamine Analogs as Inhibitors for Hyaluronan Biosynthesis

Developing inhibitors of glycan processing enzymes as tools for enabling glycobiology

(2012) Tracey M Gloster et al.   Nature Chemical Biology

A practical synthesis of capped 4-methylumbelliferyl hyaluronan disaccharides and tetrasaccharides as potential hyaluronidase substrates

(2011) Henrik Gold et al.   CARBOHYDRATE RESEARCH

Antitumor effects of hyaluronic acid inhibitor 4-methylumbelliferone in an orthotopic hepatocellular carcinoma model in mice

(2011) F. Piccioni et al.   GLYCOBIOLOGY

Inhibition of hyaluronan synthesis in breast cancer cells by 4-methylumbelliferone suppresses tumorigenicity in vitro and metastatic lesions of bone in vivo

(2011) Hiroshi Urakawa et al.   INTERNATIONAL JOURNAL OF CANCER

Peracetylated 4-Fluoro-glucosamine Reduces the Content and Repertoire ofN- andO-Glycans without Direct Incorporation

(2011) Steven R. Barthel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antitumor Activity of Hyaluronic Acid Synthesis Inhibitor 4-Methylumbelliferone in Prostate Cancer Cells

(2010) Vinata B. Lokeshwar et al.   CANCER RESEARCH

4-Methylumbelliferone inhibits hyaluronan synthesis by depletion of cellular UDP-glucuronic acid and downregulation of hyaluronan synthase 2 and 3

(2009) Anne Kultti et al.   EXPERIMENTAL CELL RESEARCH

Synthesis of UDP-glucose derivatives modified at the 3-OH as potential chain terminators of β-glucan biosynthesis

(2008) Ramona Danac et al.   CARBOHYDRATE RESEARCH