Article
Orthopedics
Jhase Sniderman, Prushoth Vivekanantha, Ajay Shah, Oleg Safir, Jesse Wolfstadt, Paul Kuzyk
Summary: This study aimed to evaluate the outcome of hemiarthroplasty compared to traditional treatment of unstable intertrochanteric fractures. It was found that hemiarthroplasty may improve outcomes for patients with unstable intertrochanteric fractures, especially in type A3 fractures.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Health Care Sciences & Services
Avishai M. Tsur, Paula David, Abdulla Watad, Daniel Nissan, Arnon D. Cohen, Howard Amital
Summary: This study found that patients with ankylosing spondylitis are more likely to develop hip fractures earlier and more frequently compared to a matched cohort. It suggests that these patients might benefit from more proactive screening, mitigation, and prevention of risk factors for hip fractures.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2022)
Article
Nutrition & Dietetics
Mengjie Yuan, Frank B. Hu, Yanping Li, Howard J. Cabral, Sai Krupa Das, Jude T. Deeney, Xinyi Zhou, Julie M. Paik, Lynn L. Moore
Summary: The study found that higher intake of total dairy, milk, and cheese is associated with lower risks of fracture in females, while yogurt intake is not associated with fracture risk.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Endocrinology & Metabolism
Thomas J. Hjelholt, Soren P. Johnsen, Peter K. Brynningsen, Grethe Andersen, Alma B. Pedersen
Summary: Considerable uncertainty exists regarding the risk factors for recurrent fracture among older patients with hip fracture. This study aimed to investigate the relationship between prefracture stroke history, baseline mobility, and the risk of recurrent hip fracture. The findings showed that stroke history was associated with the cumulative incidence of recurrent hip fracture within one year, but its association varied depending on the baseline mobility of the patients.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Article
Geriatrics & Gerontology
Samuel Hawley, Dominic Inman, Celia L. Gregson, Michael Whitehouse, Antony Johansen, Andrew Judge
Summary: This study aimed to analyze trends in returning home after hospitalization for hip fracture and identify predictive factors associated with this outcome. The findings highlighted that cognitive impairment, malnutrition, surgery delay, and early morning admission were associated with lower likelihood of discharge home, while nerve block was associated with higher likelihood of returning home. The study also revealed significant geographical variation in patient outcomes. These findings have implications for improving care and guiding future research.
Article
Geriatrics & Gerontology
Warrington W. Q. Hsu, Xiaowen Zhang, Chor-Wing Sing, Gloria H. Y. Li, Kathryn C. B. Tan, Annie W. C. Kung, Janus S. H. Wong, Ian Chi-Kei Wong, Ching-Lung Cheung
Summary: The study found that hip fracture was associated with an increased risk of dementia among older adults, especially in women. Further research on the potential role of hip fracture in the development of dementia could benefit the management of both conditions in older adults.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2022)
Article
Medicine, General & Internal
James Webster, Darren C. Greenwood, Janet E. Cade
Summary: In the UK Women's Cohort Study, vegetarian women were found to have a higher risk of hip fracture compared to regular meat-eaters. Further research is recommended to confirm this finding in men and non-European populations and to explore the factors responsible for the observed risk difference.
Article
Geriatrics & Gerontology
Sangsoo Han, Jiwon Park, Hae-Dong Jang, Sangun Nah, Joonhyeok Boo, Kyungdo Han, Jae-Young Hong
Summary: The severity of underweight is significantly associated with the risk of hip fracture. Subdivision of underweight helps estimate fracture risk more accurately.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2022)
Article
Endocrinology & Metabolism
Tuo Yang, Jing Wu, Xiang Ding, Bin Zhou, Yilin Xiong
Summary: Using propensity-score matched cohorts, this study compared the risk of hip fracture between melatonin initiators and hypnotic benzodiazepines initiators. The results showed that the initiation of melatonin was not associated with an increased risk of hip fracture. This study provides valuable insights into the potential benefits of melatonin for bone health.
OSTEOPOROSIS INTERNATIONAL
(2023)
Article
Endocrinology & Metabolism
Jiatian Li, Na Lu, Houchen Lyu, Guanghua Lei, Chao Zeng, Jie Wei, Yilun Wang, Dongxing Xie
Summary: This population-based cohort study suggests an independent association between the use of proton pump inhibitors (PPIs) and an increased risk of hip fracture in individuals with peptic ulcer disease (PUD).
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Orthopedics
Jung-Wee Park, Yong-Chan Ha, Jin-Woo Kim, Tae-Young Kim, Ji Wan Kim, Seung-Hoon Baek, Young-Kyun Lee, Kyung-Hoi Koo
Summary: The Korean Hip Fracture Registry (KHFR) Study aims to establish a nationwide prospective cohort study on hip fracture patients in order to explore the incidence and risk factors of second osteoporotic fractures. The study, launched in 2014, has enrolled 5,841 patients so far and conducted follow-up surveys to determine the occurrence of second fractures.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Article
Public, Environmental & Occupational Health
Nan Zhang, Lu Guo, Yaohui Yu, Shuohua Chen, Lishu Gao, Xiaoli Hou, Faming Tian, Shouling Wu
Summary: There is currently no data available on the risk of hip fracture after new-onset stroke in mainland China. This cohort study assessed the risk and found that stroke significantly increases the risk of hip fracture. Strategies for protecting stroke patients, particularly female, age < 60 years old, and non-obese patients, from falls and hip fractures should be emphasized in long-term management.
Article
Endocrinology & Metabolism
Fran Llopis-Cardona, Carmen Armero, Isabel Hurtado, Anibal Garcia-Sempere, Salvador Peiro, Clara L. Rodriguez-Bernal, Gabriel Sanfelix-Gimeno
Summary: Osteoporotic hip fractures in older people may increase the risk of subsequent hip fractures and death. This study estimated the cumulative incidence of recurrent hip fracture and death in the Valencia region. The findings showed that women had a higher incidence of recurrent hip fracture than men, while men had a higher risk of death.
JOURNAL OF BONE AND MINERAL RESEARCH
(2022)
Article
Medicine, General & Internal
Francois Labaste, Francois Delort, Fabrice Ferre, Fanny Bounes, Nicolas Reina, Philippe Valet, Cedric Dray, Vincent Minville
Summary: This study aimed to determine the role of postoperative delirium (POD) and postoperative neurocognitive disorders (NCDs) on the need for institutionalization at 3 months after hip fracture surgery. The study found that POD was significantly associated with the risk of long-term care, while NCDs were not. Preventing POD is essential for improving patient outcomes and the potential to return home.
FRONTIERS IN MEDICINE
(2023)
Article
Medicine, General & Internal
Sangsoo Han, Jiwon Park, Hae-Dong Jang, Kyungdo Han, Choungah Lee, Wonseok Kim, Jae-Young Hong
Summary: Change in underweight status is significantly associated with an increased risk of hip fracture.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Nutrition & Dietetics
Nicole A. Karazurna, Caitlin M. Porter, Semra Aytur, Tammy Scott, Josiemer Mattei, Sabrina E. Noel, Hector M. Gonzalez, Yasmin Mossavar-Rahmani, Daniela Sotres-Alvarez, Linda C. Gallo, Martha L. Daviglus, Linda Van Horn, Tali Elfassy, Marc D. Gellman, Ashley E. Moncrieft, Katherine L. Tucker, Robert C. Kaplan, Sherman J. Bigornia
Summary: The study aimed to investigate the association between dietary fatty acid patterns and cognitive function among Hispanic/Latino adults. The results suggest that the consumption of short to medium-chain SFA may be associated with higher cognitive function.
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Geriatrics & Gerontology
Neha Sahasrabudhe, Jong Soo Lee, Xiyuan Zhang, Tammy Scott, Laura Punnett, Katherine L. Tucker, Natalia Palacios
Summary: Higher adherence to the Mediterranean diet is associated with lower depressive symptoms, including among Latino populations such as Puerto Ricans in mainland U.S. This study found that adherence to the Mediterranean diet was negatively associated with self-reported depressive symptoms among Puerto Rican adults in the Boston area.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Geriatrics & Gerontology
Courtney L. Millar, Alyssa B. Dufour, James R. Hebert, Nitin Shivappa, Olivia Okereke, Douglas P. Kiel, Marian T. Hannan, Shivani Sahni, Roger Fielding
Summary: There is a correlation between a proinflammatory diet and increased risk of frailty, particularly among those with depressive symptoms. Further investigation is needed.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Nutrition & Dietetics
Nayla Bezares, Amanda C. McClain, Martha Tamez, Jose F. Rodriguez-Orengo, Katherine L. Tucker, Josiemer Mattei
Summary: This study examined the association between frequency and type of consuming foods away from home (FAFH) and diet quality in adults in San Juan, Puerto Rico. The results showed that frequent FAFH consumption was associated with lower diet quality and lower adherence to dietary recommendations. Future studies should explore strategies to improve diet quality, such as prioritizing healthy at-home meals and improving the quality of commercial FAFH.
JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS
(2023)
Article
Nutrition & Dietetics
Anna C. Siefkas, Courtney L. Millar, Alyssa B. Dufour, Douglas P. Kiel, Paul F. Jacques, Marian T. Hannan, Shivani Sahni
Summary: This study found that consuming yogurt was associated with a lower risk of frailty, while intake of high-fat dairy may increase the odds of frailty. However, no significant association was found between the consumption of other dairy foods and frailty in this study.
JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS
(2023)
Article
Endocrinology & Metabolism
Ching-Ti Liu, Timothy Tsai, Brett T. Allaire, Mary L. Bouxsein, Marian T. Hannan, Thomas G. Travison, Douglas P. Kiel
Summary: This study examines the association between changes in visceral adipose tissue (VAT) over 6 years and paraspinal muscle density, finding that greater accumulation of VAT is associated with lower muscle density.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Nutrition & Dietetics
Steven Oei, Courtney L. Millar, Thuy Nga Nguyen Lily, Kenneth J. Mukamal, Douglas P. Kiel, Lewis A. Lipsitz, Marian T. Hannan, Shivani Sahni
Summary: This study found that total flavonoid intake was not associated with frailty onset in adults, but higher intake of flavonols, particularly quercetin, was associated with lower odds of frailty onset. These results highlight the importance of assessing specific subclasses of flavonoids and the potential of dietary flavonols and quercetin as a strategy to prevent frailty development.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Medicine, Research & Experimental
Sha Hua, Bomin Lv, Zeping Qiu, Zhuojin Li, Zhiyan Wang, Yanjia Chen, Yanxin Han, Katherine L. Tucker, Hao Wu, Wei Jin
Summary: This study aimed to identify microbial signatures that contribute to the shared etiologies between chronic heart failure (CHF), type 2 diabetes, and chronic kidney disease. The serum levels of 151 microbial metabolites were measured in 260 individuals from the Risk Evaluation and Management of heart failure cohort, and it was found that those metabolites varied by an order of 10(5) fold. Key microbial metabolite-based risk scores were superior in CHF prognosis than the traditional Framingham or Get with the Guidelines-Heart Failure risk scores. Interactive visualization of these specific metabolite-disease links is available on our omics data server ().
EMBO MOLECULAR MEDICINE
(2023)
Article
Obstetrics & Gynecology
Ruth J. Geller, Amelia K. Wesselink, Martha R. Koenig, Michael L. Eisenberg, Katherine L. Tucker, Elizabeth E. Hatch, Lauren A. Wise
Summary: This study found weak positive associations between male fatty acid intake and fecundability among couples planning pregnancy. However, no other fatty acid subtypes were significantly associated with fecundability. This study fills a knowledge gap regarding the association between male fatty acid intake and fecundability.
HUMAN REPRODUCTION
(2023)
Article
Endocrinology & Metabolism
Danielle E. Whittier, Elizabeth J. Samelson, Marian T. Hannan, Lauren A. Burt, David A. Hanley, Emmanuel Biver, Pawel Szulc, Elisabeth Sornay-Rendu, Blandine Merle, Roland Chapurlat, Eric Lespessailles, Andy Kin On Wong, David Goltzman, Sundeep Khosla, Serge Ferrari, Mary L. Bouxsein, Douglas P. Kiel, Steven K. Boyd
Summary: This study developed a fracture risk assessment tool based on high-resolution peripheral quantitative compute tomography (HR-pQCT) to evaluate patient-specific fracture risk. The tool, called mu FRAC, outperformed the current Fracture Risk Assessment Tool (FRAX) and models based on bone mineral density (BMD). It provides an alternative approach by utilizing direct measures of bone density and structure.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Article
Nutrition & Dietetics
Liam E. Fouhy, Kelsey M. Mangano, Xiyuan Zhang, Bess Dawson Hughes, Katherine L. Tucker, Sabrina E. Noel
Summary: This study aimed to investigate the association between the calcium-to-magnesium intake ratio and bone mineral density (BMD) and osteoporosis in Puerto Rican adults. The results showed that the highest and lowest tertiles of calcium intake had higher odds of osteoporosis compared to the middle tertile.
JOURNAL OF NUTRITION
(2023)
Article
Geriatrics & Gerontology
Shivani Sahni, Alyssa B. Dufour, Na Wang, Douglas P. Kiel, Marian T. Hannan, Paul F. Jacques, Emelia J. Benjamin, Ramachandran S. Vasan, Joanne M. Murabito, Anne B. Newman, Roger A. Fielding, Gary F. Mitchell, Naomi M. Hamburg
Summary: This study examined the association between vascular health measures and grip strength and gait speed. The cross-sectional analysis showed a positive association between resting brachial artery diameter and grip strength, as well as between mean arterial pressure (MAP) and grip strength. The longitudinal analysis revealed a significant association between brachial pulse pressure and slower gait speed, but no association with grip strength.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Endocrinology & Metabolism
Jack Dalla Via, Abadi K. Gebre, Cassandra Smith, Zulqarnain Gilani, David Suter, Naeha Sharif, Pawel Szulc, John T. Schousboe, Douglas P. Kiel, Kun Zhu, William D. Leslie, Richard L. Prince, Joshua R. Lewis, Marc Sim
Summary: Abdominal aortic calcification (AAC), a measure of vascular disease, is associated with increased cardiovascular risk and poorer prognosis. An automated machine-learning algorithm has been developed for assessing AAC, which is associated with long-term incident fractures and falls.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Article
Rheumatology
Skylar Harmon, Carolina Alvarez, Marian T. Hannan, Leigh F. Callahan, Lucy S. Gates, Catherine J. Bowen, Hylton B. Menz, Amanda E. Nelson, Yvonne M. Golightly
Summary: This study aimed to evaluate the independent association between foot symptoms and all-cause mortality in older adults. The findings showed that moderate to severe foot symptoms were associated with reduced time to mortality, and this association was not influenced by walking speed or diabetes.
ARTHRITIS CARE & RESEARCH
(2023)
Article
Geriatrics & Gerontology
Rachana Raghupathy, Robert R. McLean, Douglas P. Kiel, Marian T. Hannan, Shivani Sahni
Summary: The objective of this cross-sectional study was to determine the relationship between abdominal fat and muscle health. The study found that higher abdominal fat was associated with lower muscle quality, particularly in obese women.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2023)