Liver X receptors orchestrate osteoblast/osteoclast crosstalk and counteract pathologic bone loss

Osteoprotection by semaphorin 3A

(2012) Mikihito Hayashi et al.   NATURE

Activation of Liver X Receptor (LXR) Inhibits Receptor Activator of Nuclear Factor κB Ligand (RANKL)-induced Osteoclast Differentiation in an LXRβ-dependent Mechanism

(2011) Kirsten M. Robertson Remen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osteoporosis: now and the future

(2011) Tilman D Rachner et al.   LANCET

Matrix-embedded cells control osteoclast formation

(2011) Jinhu Xiong et al.   NATURE MEDICINE

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

(2011) Tomoki Nakashima et al.   NATURE MEDICINE

Osteocytes, RANKL and bone loss

(2011) Carol Wilson   Nature Reviews Endocrinology

R-spondin 1 protects against inflammatory bone damage during murine arthritis by modulating the Wnt pathway

(2010) Gerhard Krönke et al.   ARTHRITIS AND RHEUMATISM

Short-term activation of liver X receptors inhibits osteoblasts but long-term activation does not have an impact on murine bone in vivo

(2010) Janne Prawitt et al.   BONE

Cellular communications in bone homeostasis and repair

(2010) Ken-ichi Nakahama   CELLULAR AND MOLECULAR LIFE SCIENCES

GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXR  in the hepatic acute phase response

(2010) N. Venteclef et al.   GENES & DEVELOPMENT

Cellular and Molecular Mechanisms of Bone Remodeling

(2010) Liza J. Raggatt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of adult bone turnover by sex steroids

(2010) Baruch Frenkel et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cellular mechanisms of bone remodeling

(2010) Erik Fink Eriksen   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Atypical Subtrochanteric and Femoral Shaft Fractures and Possible Association with Bisphosphonates

(2010) Jeri W. Nieves et al.   Current Osteoporosis Reports

Bone remodeling in rheumatic disease: a question of balance

(2009) Nicole C. Walsh et al.   IMMUNOLOGICAL REVIEWS

Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia

(2008) Adelheid Kratzer et al.   JOURNAL OF LIPID RESEARCH

Integration of metabolism and inflammation by lipid-activated nuclear receptors

(2008) Steven J. Bensinger et al.   NATURE