Article
Biology
Zhen Li, Sumin Gu, Yumeng Quan, Kulandaiappan Varadaraj, Jean X. Jiang
Summary: Using recombinant retroviruses containing pathogenic genes for congenital cataracts, injected into embryonic chick lenses, closely mimicked the process of cataract formation and provided a reliable in vivo system for studying the development and underlying mechanisms of cataracts and other genetic diseases.
COMMUNICATIONS BIOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Xi Sun, Yumeng Wang, Chaohui Wang, Yibin Wang, Zhouzheng Ren, Xin Yang, Xiaojun Yang, Yanli Liu
Summary: The aim of this study was to reveal the epigenetic mechanism of hepatic tran-scriptional reprogramming changes during the embryonic period of chicken. The results showed gradual increase in lipid contents and decline in H3K27ac and H3K4me2 levels with embryonic age. Differential expression genes (DEGs) were determined through transcriptome analysis. Furthermore, the integration of RNA-seq and CUT&Tag data revealed the involvement of H3K27ac histone modification in transcriptional reprogramming regulation and the recruitment of transcription factors (TFs) to mediate differential enhancer activation.
Review
Physiology
Servet Yalcin, Sezen oezkan, Tahir Shah
Summary: During incubation, temperature and light are two key factors that affect embryo development and post-hatch performance. Optimizing incubation temperature can improve hatchability, while light during incubation can enhance embryo development, reduce stress responses, and improve cognitive functions of chickens.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Paul Palmquist-Gomes, Ernesto Marin-Sedeno, Adrian Ruiz-Villalba, Gustavo Adolfo Rico-Llanos, Jose Maria Perez-Pomares, Juan Antonio Guadix
Summary: The presence of cartilage tissue in the hearts of vertebrate species has long been recognized. Recent findings suggest that epicardial lineage cells can differentiate into chondrocytes, challenging the historical view that the embryonic neural crest is the main source of cardiac cartilage. This study demonstrates the formation of cardiac cartilage clusters from proepicardial cells, supporting the concept of proepicardial cells as multipotent connective progenitors. These findings have important implications for understanding cardiac cell complexity and responses to pathological stimuli.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biology
Shizhen Qin, Liang Huang, Lin Lu, Liyang Zhang, Yanli Guo, Lin Xi, Xiudong Liao, Xugang Luo
Summary: Manganese is a necessary trace element that can alleviate the negative effects of heat stress on the heart of broiler breeders and embryos, but the mechanisms behind this protection are still unclear. Two experiments were conducted to investigate the protective effects of manganese on primary cultured chick embryonic myocardial cells exposed to heat challenge. The results showed that supplementation of manganese could enhance the expression of manganese superoxide dismutase and attenuate heat shock response, protecting the myocardial cells from heat-induced damage.
JOURNAL OF THERMAL BIOLOGY
(2023)
Article
Cell Biology
Younes F. Barooji, Kasper G. Hvid, Irene Isturiz Petitjean, Joshua M. Brickman, Lene B. Oddershede, Poul M. Bendix
Summary: The 3D actin cytoskeleton of naive mouse ESCs was investigated, revealing significant changes in peripheral actin structure and micro-rheological differences between cells cultured in different media. These results pave the way for linking physical properties and cytoskeletal architecture to cell morphology during early development.
Article
Robotics
Xinjia Huang, Xiangyang Zhu, Guoying Gu
Summary: This article presents a general framework for the design, kinematic modeling, model-based characterization, and control of soft parallel robots. The developed continuum-based model accurately describes the configuration and deformation of the robot. The model is validated through experiments on the robot's workspace and stiffness, and a model-based trajectory tracking controller is established.
IEEE TRANSACTIONS ON ROBOTICS
(2022)
Article
Biochemistry & Molecular Biology
Clara Bartra, Lars Andre Jager, Anna Alcarraz, Aline Meza-Ramos, Gemma Sanguesa, Ruben Corpas, Eduard Guasch, Montserrat Batlle, Coral Sanfeliu
Summary: Physically active lifestyle has significant implications for the health and well-being, but excessive training can lead to cardiovascular events and impaired brain plasticity. In this study, young adult male mice were subjected to moderate or high-intensity treadmill running for eight weeks. The high-intensity training resulted in decreased weight gain and cardiac hypertrophy, but without hemodynamic overload. It also reduced heart rate and improved motor skills, without impairing recognition or spatial memory.
Article
Engineering, Biomedical
Zhengpei Zhang, Farasat Zaman, Tobia Sebastiano Nava, Tim R. J. Aeppli, Elena M. Gutierrez-Farewik, Artem Kulachenko, Lars Savendahl
Summary: To study the potential clinical applications of mechanical loading in modulating bone growth, a portable loading device was developed. The device allows high-precision force control and can have different effects on bone growth. This device enables further preclinical studies exploring the potential clinical applications of mechanical loading.
ANNALS OF BIOMEDICAL ENGINEERING
(2023)
Article
Geochemistry & Geophysics
N. L. Bennington, S. J. Ohlendorf, C. H. Thurber, M. M. Haney
Summary: This study uses ambient noise interferometry to investigate temporal changes in seismic velocity at Okmok volcano in Alaska during the inter-eruptive period between two eruptions. The depth-constrained changes in seismic velocity distinguish volcanic and non-volcanic processes, and theoretical volumetric strain modeling of volcanic deformation is also conducted. The joint analysis technique developed in this study allows for the determination of volcanic deformation location, with potential implications for monitoring active magma storage at sparsely instrumented volcanoes worldwide.
EARTH AND PLANETARY SCIENCE LETTERS
(2021)
Article
Engineering, Electrical & Electronic
Bin Wang, Ramon Costa-Castello, Jing Na, Oscar de la Torre, Xavier Escaler
Summary: This paper proposes a new adaptive estimation approach for online parameter estimation of a piezoelectric cantilever beam. By introducing the Galerkin method and separating the time and space variables of the PDE, the unknown parameters of the derived ODE model can be estimated in real time.
IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS I-REGULAR PAPERS
(2023)
Article
Chemistry, Multidisciplinary
Yizong Chen, Jian Li, Shenghai Wang, Guangdong Han, Yuqing Sun
Summary: In this article, a new type of cable-driven parallel derusting robot (CDPDR) is proposed to address the complex and labor-intensive task of ship derusting. The system's dynamic model, controllable workspace, and cable tension optimization algorithm are established and studied to improve positioning accuracy and anti-interference capacity. A fast non-singular terminal sliding-mode controller is designed and the stability of the system is proven using Lyapunov theory. High-fidelity simulations demonstrate the controller's ability to converge in finite time and maintain small error under multiple external disturbances, providing theoretical guidance for the application of CDPDRs on ships.
APPLIED SCIENCES-BASEL
(2022)
Article
Engineering, Mechanical
Fucheng Tian, Mengnan Zhang, Jun Zeng, Bin Li, Liangbin Li
Summary: The recently proposed mixed displacement-pressure-phase field formulation is highly effective in fracture modeling of nearly incompressible hyperelastic materials. To overcome the limitations of existing formulations, a stabilized mixed formulation (P1/P1S) is developed, which allows for low-order P1 interpolation for all field variables. An efficient adaptive meshing strategy is designed to speed up computation by more than 15 times, while a novel energy-based mesh refinement criterion is proposed for better handling of crack nucleation in adaptive scenarios. The accuracy, efficiency, and robustness of the proposed formulation are validated through numerical examples, showing promising results.
INTERNATIONAL JOURNAL OF MECHANICAL SCIENCES
(2022)
Article
Engineering, Mechanical
M. Wronski, M. Arul Kumar, R. J. McCabe, K. Wierzbanowski, C. N. Tome
Summary: The deformation behavior of commercially pure rolled titanium under strain path changes was studied using experiments and a crystal plasticity model, considering different loading combinations to investigate slip, twinning, de-twinning, and double-twinning in hexagonal closed packed titanium. An EBSD-based analysis was used to study the evolution of {1012} tensile and {1122} compression twins, supporting the model results. The VPSC model successfully predicted the evolution of twinning and twin volume fraction under strain path changes, with results in agreement with experimental observations.
INTERNATIONAL JOURNAL OF PLASTICITY
(2022)
Article
Acoustics
Rashid Al Mukaddim, Ashley M. Weichmann, Rachel Taylor, Timothy A. Hacker, Thomas Pier, Joseph Hardin, Melissa Graham, Elizabeth M. Casper, Carol C. Mitchell, Tomy Varghese
Summary: Bayesian regularized cardiac strain imaging (ABR-CSI) uses raw radiofrequency signals to estimate myocardial wall contractility and shows the potential for non-invasive detection of cardiac remodeling. The study validated the findings against ground truth histology and found correlations between strain estimates and cardiac fibrosis.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2023)
